公开(公告)号：WO2010016064A3

公开(公告)日：2010-05-06

申请号：PCT/IL2009000765

申请日：2009-08-05

Applicant: ROSETTA GENOMICS LTD ,  TEL HASHOMER MEDICAL INFRASTRU ,  ROSENFELD NITZAN ,  SPECTOR YAEL ,  FRIEDMAN EDDIE ,  DOTAN ZOHAR

Inventor： ROSENFELD NITZAN ,  SPECTOR YAEL ,  FRIEDMAN EDDIE ,  DOTAN ZOHAR

IPC: C12Q1/68

CPC classification number: C12Q1/68 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/178

Abstract: The present invention provides a method for classification of kidney tumors through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA expression framework allows optimization of treatment, and determination of specific therapy.

Abstract translation: 本发明提供了通过分析特定微RNA和与其相关的核酸分子的表达模式来分类肾肿瘤的方法。 根据microRNA表达框架进行分类可以优化治疗，并确定具体的治疗方法。

公开(公告)号：WO2010070637A2

公开(公告)日：2010-06-24

申请号：PCT/IL2009/001181

申请日：2009-12-13

Applicant: ROSETTA GENOMICS LTD. ,  MOR RESEARCH APPLICATIONS ,  SPECTOR, Yael ,  FEINMESSER, Meora

Inventor： SPECTOR, Yael ,  FEINMESSER, Meora

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/158 ,  C12Q2600/178

Abstract: The present invention provides nucleic acid sequences that are used for identification, classification and diagnosis of specific types of adrenal tumors. The nucleic acid sequences can also be used for evaluation of a subject based on the expression pattern of a biological sample.

Abstract translation: 本发明提供了用于特定类型的肾上腺肿瘤的鉴定，分类和诊断的核酸序列。 核酸序列也可以用于基于生物样品的表达模式来评估受试者。

公开(公告)号：WO2010016064A2

公开(公告)日：2010-02-11

申请号：PCT/IL2009/000765

申请日：2009-08-05

Applicant: ROSETTA GENOMICS LTD. ,  TEL HASHOMER MEDICAL INFRASTRUCTURE AND SERVICES LTD. ,  ROSENFELD, Nitzan ,  SPECTOR, Yael ,  FRIEDMAN, Eddie ,  DOTAN, Zohar

Inventor： ROSENFELD, Nitzan ,  SPECTOR, Yael ,  FRIEDMAN, Eddie ,  DOTAN, Zohar

IPC: C12Q1/68

CPC classification number: C12Q1/68 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/178

Abstract: The present invention provides a method for classification of kidney tumors through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA expression framework allows optimization of treatment, and determination of specific therapy.

Abstract translation: 本发明提供了通过分析与其有关的特异性微小RNA和核酸分子的表达模式来分类肾肿瘤的方法。 根据microRNA表达框架进行分类可以优化治疗，并确定特异性治疗。

公开(公告)号：WO2015175660A1

公开(公告)日：2015-11-19

申请号：PCT/US2015/030564

申请日：2015-05-13

Applicant: ROSETTA GENOMICS, LTD. ,  BARNETT-ITZHAKI, Zohar ,  LITHWICK YANAI, Gila ,  MEIRI, Eti ,  SPECTOR, Yael ,  BENJAMIN, Hila

Inventor： BARNETT-ITZHAKI, Zohar ,  LITHWICK YANAI, Gila ,  MEIRI, Eti ,  SPECTOR, Yael ,  BENJAMIN, Hila

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/158 ,  C12Q2600/178

Abstract: The present invention provides a method for classification of thyroid tumors through the analysis of the expression patterns of specific microRNAs in fine needle aspiration samples. Thyroid tumor classification according to a microRNA expression signature allows optimization of diagnosis and treatment, as well as determination of signature-specific therapy.

Abstract translation: 本发明提供了通过分析细针抽吸样品中特异性微小RNA的表达模式来分类甲状腺肿瘤的方法。 根据微小RNA表达特征的甲状腺肿瘤分类可以优化诊断和治疗，以及确定特异性特异性治疗。

公开(公告)号：WO2010070637A3

公开(公告)日：2010-08-12

申请号：PCT/IL2009001181

申请日：2009-12-13

Applicant: ROSETTA GENOMICS LTD ,  MOR RES APPLIC ,  SPECTOR YAEL ,  FEINMESSER MEORA

Inventor： SPECTOR YAEL ,  FEINMESSER MEORA

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/158 ,  C12Q2600/178

Abstract: The present invention provides nucleic acid sequences that are used for identification, classification and diagnosis of specific types of adrenal tumors. The nucleic acid sequences can also be used for evaluation of a subject based on the expression pattern of a biological sample.

Abstract translation: 本发明提供了用于鉴别，分类和诊断特定类型的肾上腺肿瘤的核酸序列。 基于生物样品的表达模式，核酸序列也可以用于评估受试者。