公开(公告)号：WO2012031299A3

公开(公告)日：2012-08-16

申请号：PCT/US2011050561

申请日：2011-09-06

Applicant: VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH ,  STEPHANI THOMAS ,  BEHRENS UWE ,  ROECKEN HEINRICH ,  BAUMGARTEN CHRISTIAN ,  TIMMER JAN ,  HAO JAMES P

Inventor： STEPHANI THOMAS ,  BEHRENS UWE ,  ROECKEN HEINRICH ,  BAUMGARTEN CHRISTIAN ,  TIMMER JAN

IPC: A61N5/10 ,  H05H13/00

CPC classification number: H05H7/02 ,  A61N5/10 ,  A61N5/1077 ,  A61N2005/1087 ,  H01J3/14 ,  H05H13/005 ,  H05H2007/122 ,  H05H2277/11

Abstract: Systems and methods are provided to perform efficient, automatic adjustment of cyclotron beam currents within a wide range for multiple treatment layers within the same patient and treatment session; and to perform efficient, automatic cyclotron initialization, and calibration. In an embodiment, efficient adjustment is achieved by using beam current attenuation by an electrostatic vertical deflector installed in the inner center of the cyclotron. The beam current may, for example, be adjusted by the high voltage applied to the electrostatic vertical deflector, in front of each treatment the attenuation curve of the vertical deflector is recorded. Based on this attenuation curve, the vertical deflector voltage for the needed beam current of each irradiation layer is interpolated. In another embodiment, a process is provided that allows the automation of the initialization of a cyclotron after overnight or maintenance imposed shutdown. In one embodiment, five independent cyclotron system states are defined and the transition between one state to another may be automated, e.g., by the control system of the cyclotron.

Abstract translation: 提供系统和方法以在相同的患者和治疗期内对多个治疗层在宽范围内执行高效的自动调节回旋束电流; 并执行高效的自动回旋加速器初始化和校准。 在一个实施例中，通过使用安装在回旋加速器内部中心的静电垂直偏转器的束电流衰减来实现有效调节。 束流例如可以通过施加到静电垂直偏转器的高电压来调节，在每次处理之前记录垂直偏转器的衰减曲线。 基于该衰减曲线，内插每个照射层所需射束电流的垂直偏转器电压。 在另一个实施例中，提供了一种过程，该过程允许在隔夜或维护强制关机后自动化回旋加速器的初始化。 在一个实施例中，定义了五个独立的回旋加速器系统状态，并且一个状态到另一个状态之间的转换可以例如通过回旋加速器的控制系统自动化。

公开(公告)号：WO2012031299A2

公开(公告)日：2012-03-08

申请号：PCT/US2011/050561

申请日：2011-09-06

Applicant: VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH ,  STEPHANI, Thomas ,  BEHRENS, Uwe ,  ROECKEN, Heinrich ,  BAUMGARTEN, Christian ,  TIMMER, Jan ,  HAO, James, P.

Inventor： STEPHANI, Thomas ,  BEHRENS, Uwe ,  ROECKEN, Heinrich ,  BAUMGARTEN, Christian ,  TIMMER, Jan

IPC: A61N5/10 ,  H05H13/00

CPC classification number: H05H7/02 ,  A61N5/10 ,  A61N5/1077 ,  A61N2005/1087 ,  H01J3/14 ,  H05H13/005 ,  H05H2007/122 ,  H05H2277/11

Abstract: Systems and methods are provided to perform efficient, automatic adjustment of cyclotron beam currents within a wide range for multiple treatment layers within the same patient and treatment session; and to perform efficient, automatic cyclotron initialization, and calibration. In an embodiment, efficient adjustment is achieved by using beam current attenuation by an electrostatic vertical deflector installed in the inner center of the cyclotron. The beam current may, for example, be adjusted by the high voltage applied to the electrostatic vertical deflector, in front of each treatment the attenuation curve of the vertical deflector is recorded. Based on this attenuation curve, the vertical deflector voltage for the needed beam current of each irradiation layer is interpolated. In another embodiment, a process is provided that allows the automation of the initialization of a cyclotron after overnight or maintenance imposed shutdown. In one embodiment, five independent cyclotron system states are defined and the transition between one state to another may be automated, e.g., by the control system of the cyclotron.

Abstract translation: 提供系统和方法以在相同的患者和治疗期间内的多个治疗层的范围内对回旋加速器束电流进行有效的自动调节; 并执行有效的自动回旋加速器初始化和校准。 在一个实施例中，通过使用安装在回旋加速器的内部中心的静电垂直偏转器来使用束流衰减来实现有效的调节。 例如，通过施加到静电垂直偏转器的高电压来调节束电流，在每个处理前面记录垂直偏转器的衰减曲线。 基于该衰减曲线，对每个照射层所需的束电流的垂直偏转器电压进行插值。 在另一个实施例中，提供了一种过程，其允许在过夜或维护强制停机之后对回旋加速器的初始化进行自动化。 在一个实施例中，定义了五个独立的回旋加速器系统状态，并且一个状态与另一个状态之间的转换可以例如由回旋加速器的控制系统自动化。