SYSTEM AND METHOD USING COUPLER-RESONATORS FOR ELECTRON PARAMAGNETIC RESONANCE SPECTROSCOPY
    1.
    发明申请
    SYSTEM AND METHOD USING COUPLER-RESONATORS FOR ELECTRON PARAMAGNETIC RESONANCE SPECTROSCOPY 审中-公开
    使用耦合器谐振器进行电子参考共振光谱的系统和方法

    公开(公告)号:WO2010053609A2

    公开(公告)日:2010-05-14

    申请号:PCT/US2009/052261

    申请日:2009-07-30

    Abstract: A coupler-resonator for electron paramagnetic resonance (EPR) spectroscopy in subjects has a wire loop formed into a coupling loop, a central transmission portion, and sensor loops. The sensor loops hold EPR sensor materials and are coated with biocompatible plastic. The coupler-resonator is implanted in a subject, the subject in a nonuniform magnetic field with a pickup coil for RF response measurement apparatus near the subject's skin and inductively coupled to the coupling loop. Resonances are measured at multiple sensor loops distinguished by sweeping magnetic field or radio frequency. A biopsy sampler has an outer needle with sensor loop and a central sampling needle with cavity for biopsy samples and EPR sensor material. A device for EPR of fingernails has sensor loops in a partial glove for holding loops next to fingertips. A device for EPR of teeth has sensor loops in plastic chips that can be held between the teeth.

    Abstract translation: 受试者中用于电子顺磁共振(EPR)光谱的耦合器谐振器具有形成耦合回路,中心传输部分和传感器环路的线环。 传感器回路保持EPR传感器材料,并涂有生物相容的塑料。 耦合器谐振器被植入受试者中,受试者在不均匀的磁场中与受试者皮肤附近的用于RF响应测量装置的拾波线圈感应耦合到耦合回路。 在通过扫描磁场或射频区分的多个传感器环路上测量共振。 活检取样器具有带传感器环的外针和具有用于活检样本和EPR传感器材料的空腔的中心采样针。 用于指甲EPR的装置具有部分手套中的传感器环,用于在指尖附近保持环。 用于EPR齿的装置具有能够保持在齿之间的塑料芯片的传感器回路。

    SYSTEM AND METHOD USING COUPLER-RESONATORS FOR ELECTRON PARAMAGNETIC RESONANCE SPECTROSCOPY
    5.
    发明申请
    SYSTEM AND METHOD USING COUPLER-RESONATORS FOR ELECTRON PARAMAGNETIC RESONANCE SPECTROSCOPY 审中-公开
    用耦合共振器进行电子顺磁共振谱的系统和方法

    公开(公告)号:WO2010053609A9

    公开(公告)日:2010-08-26

    申请号:PCT/US2009052261

    申请日:2009-07-30

    Abstract: A coupler-resonator for electron paramagnetic resonance (EPR) spectroscopy in subjects has a wire loop formed into a coupling loop, a central transmission portion, and sensor loops. The sensor loops hold EPR sensor materials and are coated with biocompatible plastic. The coupler-resonator is implanted in a subject, the subject in a nonuniform magnetic field with a pickup coil for RF response measurement apparatus near the subject's skin and inductively coupled to the coupling loop. Resonances are measured at multiple sensor loops distinguished by sweeping magnetic field or radio frequency. A biopsy sampler has an outer needle with sensor loop and a central sampling needle with cavity for biopsy samples and EPR sensor material. A device for EPR of fingernails has sensor loops in a partial glove for holding loops next to fingertips. A device for EPR of teeth has sensor loops in plastic chips that can be held between the teeth.

    Abstract translation: 用于受试者中电子顺磁共振(EPR)光谱学的耦合器 - 谐振器具有形成耦合环路,中心传输部分和传感器环路的导线环路。 传感器环路保持EPR传感器材料并涂有生物相容性塑料。 耦合谐振器植入受试者体内,受试者处于非均匀磁场中,在受试者皮肤附近具有用于RF响应测量装置的拾取线圈并且与耦合回路感应耦合。 谐振是在多个传感器回路测量的,通过扫描磁场或射频来区分。 活检采样器具有带传感器环的外针和带有用于活检样本和EPR传感器材料的腔的中央采样针。 用于手指甲的EPR的装置在部分手套中具有传感器环,用于将指尖附近的环扣住。 用于牙齿EPR的装置具有塑料片中的传感器环,其可以保持在牙齿之间。

    SYSTEM AND METHOD FOR POST-EXPOSURE DOSIMETRY USING ELECTRON PARAMAGNETIC RESONANCE SPECTROSCOPY
    6.
    发明申请
    SYSTEM AND METHOD FOR POST-EXPOSURE DOSIMETRY USING ELECTRON PARAMAGNETIC RESONANCE SPECTROSCOPY 审中-公开
    使用电子顺磁共振谱的曝光后剂量图的系统和方法

    公开(公告)号:WO2010047879A2

    公开(公告)日:2010-04-29

    申请号:PCT/US2009055414

    申请日:2009-08-28

    CPC classification number: G01N24/10 G01R33/60

    Abstract: An apparatus and method for triaging patients according to radiation exposure operates by measuring electron paramagnetic resonance spectra of fingernails, toenails, and/or teeth. When operating in vivo, radiation induced spectra are obtained from intact fingernails, toenails, or teeth placed within a magnet and with pickup coils located over nails between the cut edge at the end of the fingernail and skin proximal to the nail or placed adjacent to at least one tooth. When operating in vitro with fingernail clippings, one or more spectra are obtained. In an embodiment, at least three spectra are obtained with at least one after a delay at above twenty degrees Celsius, and at least one at power levels different from the others. The three spectra are used to determine and remove a mechanically induced signal from EPR spectra to determine radiation-induced spectra. The radiation induced spectra are used to determine a radiation dose, the dose is compared to triage limits, and a radiological triage tag is printed for the patients.

    Abstract translation: 根据辐射暴露对患者进行分类的设备和方法通过测量指甲,脚趾甲和/或牙齿的电子顺磁共振谱来操作。 当在体内操作时,辐射诱导光谱是从完整的指甲,脚趾甲或放置在磁体内的牙齿获得的,并且拾取线圈位于指甲末端的切割边缘和指甲近端的皮肤之间的指甲上,或者位于指甲的邻近 至少一颗牙齿。 当用指甲剪在体外进行操作时,获得一个或多个光谱。 在一个实施例中,在高于二十摄氏度的延迟之后至少一个获得至少三个频谱,并且在至少一个与其他频率不同的功率水平下获得至少三个频谱。 这三个光谱用于确定和去除EPR光谱中的机械感应信号以确定辐射诱导光谱。 辐射诱导光谱用于确定辐射剂量,将剂量与分诊极限进行比较,并为患者打印放射分类标签。

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