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公开(公告)号：WO2014150937A1
公开(公告)日：2014-09-25
申请号：PCT/US2014/024597
申请日：2014-03-12
申请人： NOVARTIS AG , IRM LLC , ABRAMS, Tinya , COHEN, Steven , FANTON, Christie P. , HUBER, Thomas , MILLER, Kathy , SCHLEYER, Siew Ho , TISSOT-DAGUETTE, Kathrin Ulrike , FINNER, Catrin
发明人： ABRAMS, Tinya , COHEN, Steven , FANTON, Christie P. , HUBER, Thomas , MILLER, Kathy , SCHLEYER, Siew Ho , TISSOT-DAGUETTE, Kathrin Ulrike , FINNER, Catrin
CPC分类号： A61K47/6803 , A61K9/0019 , A61K9/19 , A61K31/537 , A61K45/06 , A61K47/12 , A61K47/26 , A61K47/6801 , A61K47/6849 , A61K47/6855 , A61K47/6857 , A61K47/6865 , A61K47/6867 , A61K47/6889 , A61K49/00 , A61K51/103 , A61K51/1093 , A61K2039/505 , C07K16/2803 , C07K16/2863 , C07K16/32 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92
摘要： The present invention relates to anti-cKIT antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
摘要翻译： 本发明涉及抗cKIT抗体，抗体片段，抗体药物偶联物及其用于治疗癌症的用途。
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公开(公告)号：WO2016020791A1
公开(公告)日：2016-02-11
申请号：PCT/IB2015/055678
申请日：2015-07-27
申请人： NOVARTIS AG , ABRAMS, Tinya , COHEN, Steven Bruce , DANIEL, Dylan , FINNER, Catrin , GEIERSTANGER, Bernhard Hubert , HUBER, Thomas , MALLET, William , MEYER, Matthew John , OU, Weijia , SCHLEYER, Siew Ho , TISSOT-DAGUETTE, Kathrin Ulrike
发明人： ABRAMS, Tinya , COHEN, Steven Bruce , DANIEL, Dylan , FINNER, Catrin , GEIERSTANGER, Bernhard Hubert , HUBER, Thomas , MALLET, William , MEYER, Matthew John , OU, Weijia , SCHLEYER, Siew Ho , TISSOT-DAGUETTE, Kathrin Ulrike
CPC分类号： A61K47/6803 , A61K39/39558 , A61K47/6849 , A61K49/00 , A61K51/103 , A61K51/1093 , A61K2039/505 , A61K2039/545 , A61P35/02 , C07K16/2803 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/77 , C07K2317/92
摘要： The present invention relates to anti-cKIT antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
摘要翻译： 本发明涉及抗cKIT抗体，抗体片段，抗体药物偶联物及其用于治疗癌症的用途。
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3.发明申请ANTIBODIES TARGETING BONE MORPHOGENETIC PROTEIN 9 (BMP9) AND METHODS THEREFOR 审中-公开靶向骨形态蛋白9（BMP9）的抗体及其方法
公开(公告)号：WO2016193872A2
公开(公告)日：2016-12-08
申请号：PCT/IB2016/053095
申请日：2016-05-26
申请人： NOVARTIS AG , CHEN, Zijun , DENG, Sujun , HE, Yun , HUANG, Dagang , KUGLER, Markus , LI, Qian , LU, Chris Xiangyang , LUO, Xiao , SHAN, Yongqiang , TISSOT-DAGUETTE, Kathrin Ulrike , WU, Jing
发明人： CHEN, Zijun , DENG, Sujun , HE, Yun , HUANG, Dagang , KUGLER, Markus , LI, Qian , LU, Chris Xiangyang , LUO, Xiao , SHAN, Yongqiang , TISSOT-DAGUETTE, Kathrin Ulrike , WU, Jing
CPC分类号： C07K16/22 , A61K31/155 , A61K31/355 , A61K31/4439 , A61K31/4725 , A61K31/497 , A61K31/513 , A61K31/522 , A61K31/575 , A61K31/675 , A61K31/7072 , A61K38/1875 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , C12N15/09 , C12N15/63 , A61K2300/00
摘要： The present invention relates to isolated antibodies and antigen-binding fragments thereof which bind human BMP9 and compositions and methods of use thereof.
摘要翻译： 本发明涉及结合人BMP9的分离的抗体及其抗原结合片段及其组合物及其使用方法。
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4.发明申请ANTIBODIES TARGETING BONE MORPHOGENETIC PROTEIN 9 (BMP9) AND METHODS THEREFOR 审中-公开靶向骨形态蛋白9（BMP9）的抗体及其方法
公开(公告)号：WO2016193872A3
公开(公告)日：2017-03-30
申请号：PCT/IB2016053095
申请日：2016-05-26
申请人： NOVARTIS AG , CHEN ZIJUN , DENG SUJUN , HE YUN , HUANG DAGANG , KUGLER MARKUS , LI QIAN , LU CHRIS XIANGYANG , LUO XIAO , SHAN YONGQIANG , TISSOT-DAGUETTE KATHRIN ULRIKE , WU JING
发明人： CHEN ZIJUN , DENG SUJUN , HE YUN , HUANG DAGANG , KUGLER MARKUS , LI QIAN , LU CHRIS XIANGYANG , LUO XIAO , SHAN YONGQIANG , TISSOT-DAGUETTE KATHRIN ULRIKE , WU JING
IPC分类号： C07K16/22 , A61K39/00 , A61K39/395 , A61K45/06
CPC分类号： C07K16/22 , A61K31/155 , A61K31/355 , A61K31/4439 , A61K31/4725 , A61K31/497 , A61K31/513 , A61K31/522 , A61K31/575 , A61K31/675 , A61K31/7072 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , A61K2300/00
摘要： The present invention relates to isolated antibodies and antigen-binding fragments thereof which bind human BMP9 and compositions and methods of use thereof.
摘要翻译： 本发明涉及结合人BMP9的分离的抗体及其抗原结合片段及其组合物及其使用方法。
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