OFF-TASTE MASKING
    3.
    发明申请
    OFF-TASTE MASKING 审中-公开
    非吸收性掩蔽

    公开(公告)号:WO2010100158A1

    公开(公告)日:2010-09-10

    申请号:PCT/EP2010/052633

    申请日:2010-03-02

    IPC分类号: A23L1/236 A23L1/22

    CPC分类号: A23L27/30 A23L27/84

    摘要: A method of masking the off-taste of an artificial or natural sweetener, comprising the addition to the sweetener of at least one compound according to the formula (I), in which R1 is selected from H, C 1 -C 4 alkyl and Ph; R2 is selected from H and Me; R3 is selected from H, C 1 -C 4 alkyl and Ph; R4 is selected from H and C 1 -C 4 alkyl: or R3, R4 together form a five, six or seven-membered aliphatic ring.

    摘要翻译: 掩蔽人造或天然甜味剂的异味的方法,包括向甜味剂中加入至少一种根据式(I)的化合物,其中R 1选自H,C 1 -C 4烷基和Ph; R2选自H和Me; R 3选自H,C 1 -C 4烷基和Ph; R4选自H和C1-C4烷基:或R3,R4一起形成五,六或七元脂族环。

    AMIDE ADDITION REACTION
    6.
    发明申请
    AMIDE ADDITION REACTION 审中-公开
    酰胺添加反应

    公开(公告)号:WO2009012609A1

    公开(公告)日:2009-01-29

    申请号:PCT/CH2008/000325

    申请日:2008-07-21

    IPC分类号: C07D213/127

    CPC分类号: C07D213/127

    摘要: A method of making a compound of formula (II) comprising the reaction of a compound of formula RCONH 2 with a compound of formula (III) R being a moiety having between 1 and 15 carbon atoms and optionally from 1 to 5 heteroatoms independently selected from oxygen, nitrogen and sulfur, and X and Y being independently selected from the group consisting of H, methyl, ethyl, OMe, Oet, and mixtures thereof; the reaction being performed in a solvent in the presence of a base. The method is useful for the inexpensive manufacture of certain commercially-valuable compounds, including some that have desirable cooling properties.

    摘要翻译: 制备式(II)化合物的方法,其包括式RCONH2化合物与式(III)化合物的反应,R是具有1至15个碳原子和任选地1至5个独立地选自氧的杂原子的部分 ,氮和硫,X和Y独立地选自H,甲基,乙基,OMe,Oet及其混合物; 反应在溶剂中在碱的存在下进行。 该方法对于廉价制造某些商业上有价值的化合物是有用的,包括一些具有期望的冷却性质的化合物。