公开(公告)号：WO2012062885A2

公开(公告)日：2012-05-18

申请号：PCT/EP2011069889

申请日：2011-11-10

Applicant: UNIV ZUERICH PROREKTORAT MNW ,  NARAYANA RAO JAI ANAND GARG ,  SZENTKUTI ALEXANDER ZALAN CLAUDE ,  VENKATESAN KOUSHIK

Inventor： NARAYANA RAO JAI ANAND GARG ,  SZENTKUTI ALEXANDER ZALAN CLAUDE ,  VENKATESAN KOUSHIK

IPC: C07F1/12

CPC classification number: H01L51/0084 ,  C07F1/00 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1014 ,  C09K2211/1029 ,  C09K2211/1092 ,  C09K2211/188 ,  H01L51/0091 ,  H01L51/5016 ,  H05B33/10

Abstract: A process for the preparation of monocyclometalated Au(III) complexes, cis- [(N?C)AuL1L2] and czs-[(N?C)AuL1AL2] represented by generic chemical formulae la and lb respectively with ligands L1 and L2 being either similar (L1=L2) or dissimi lar (L1? L2) but with at least one of either (L1 or L2) comprising a s-donating carbanionic group is described here. L3 in formula lc denotes a neutral donor ligand bound in a tridentate fashion. The complexes depicted by the formulae 1a, 1b and 1c in the present invention are suitable as emissive phosphorescent organometallic materials in OLEDs.

Abstract translation: 由通用化学式Ia和1b分别代表的单配金属Au（III）配合物，顺式 - [（N 2 C）AuL 1 L 2]和czs - [（N 2 C）AuL 1 AL 2]的制备方法，其中配体L1和L2分别为 这里描述了类似的（L1 = L2）或不同的（L1→L2），但是与包含s-供体的碳负离子基团的（L1或L2）中的至少一个有关。 式lc中的L3表示以三齿方式结合的中性供体配体。 在本发明中由式1a，1b和1c描述的络合物适合作为OLED中的发射磷光有机金属材料。

公开(公告)号：WO2010046289A3

公开(公告)日：2011-02-17

申请号：PCT/EP2009063406

申请日：2009-10-14

Applicant: UNIV ZUERICH PROREKTORAT MNW ,  HEIKENWAELDER MATHIAS ,  AGUZZI ADRIANO

Inventor： HEIKENWAELDER MATHIAS ,  AGUZZI ADRIANO

IPC: A61K39/395 ,  A61P1/16 ,  A61P31/12 ,  A61P35/00 ,  C07K16/24 ,  C12N15/113

CPC classification number: C07K16/242 ,  A61K2039/505 ,  C07K16/2878 ,  C07K2317/76 ,  C07K2319/30 ,  C07K2319/32

Abstract: The present invention relates to a method of preventing and treating chronic hepatitis and other liver diseases comprising administering a blocker of Light, LTa1ß2, LTa2ß1 or LTßR, and the use of such blockers in said prevention and treatment and in the manufacture of medicaments for preventing and treating chronic hepatitis and other liver diseases.

Abstract translation: 本发明涉及一种预防和治疗慢性肝炎及其他肝病的方法，包括给予Light，LTa1β2，LTa2β1或LTβR的阻断剂，以及在所述预防和治疗和制造用于预防和/ 治疗慢性肝炎等肝病。

公开(公告)号：WO2012140148A3

公开(公告)日：2012-12-20

申请号：PCT/EP2012056693

申请日：2012-04-12

Applicant: UNIV ZUERICH PROREKTORAT MNW ,  COOKSLEY-DECASPER SERAINA ,  HOF DANIELLE ,  VON ECKARDSTEIN ARNOLD

Inventor： COOKSLEY-DECASPER SERAINA ,  HOF DANIELLE ,  VON ECKARDSTEIN ARNOLD

IPC: G01N33/68

CPC classification number: G01N33/6893 ,  G01N2333/795 ,  G01N2800/32 ,  G01N2800/323

Abstract: The invention relates to a method for diagnosis of cardiovascular disease in a patient, com detecting, in a sample obtained from said patient, junction plakoglobin (SEQ ID 001) or a polypeptide related thereto. It further relates to devices and kits for detection of junction plakoglobin.

Abstract translation: 本发明涉及用于诊断患者心血管疾病的方法，其在从所述患者获得的样品中检测连接蛋白（SEQ ID NO：001）或与其相关的多肽。 它进一步涉及用于检测结合红血球蛋白的装置和试剂盒。

公开(公告)号：WO2010026213A3

公开(公告)日：2010-05-27

申请号：PCT/EP2009061454

申请日：2009-09-04

Applicant: UNIV ZUERICH PROREKTORAT MNW ,  GAY STEFFEN ,  DISTLER OLIVER ,  MAURER BRITTA

Inventor： GAY STEFFEN ,  DISTLER OLIVER ,  MAURER BRITTA

IPC: A61K31/713

CPC classification number: A61K31/713

Abstract: The present invention provides a method of treating scleroderma. The method consists in the upregulation of miR-29 by administration of miR-29 or a miR-29 upregulator which elevates circulating and/or intracellular concentrations of miR-29. The invention likewise relates to the use of miR-29 for such a treatment, and the use of miR-29 for the manufacture of a medicament for the treatment of scleroderma.

Abstract translation: 本发明提供一种治疗硬皮病的方法。 该方法包括通过施用提高miR-29的循环和/或细胞内浓度的miR-29或miR-29上调来上调miR-29。 本发明同样涉及miR-29用于这种治疗的用途，以及miR-29在制备用于治疗硬皮病的药物中的用途。

公开(公告)号：WO2010022882A3

公开(公告)日：2010-08-19

申请号：PCT/EP2009006003

申请日：2009-08-19

Applicant: UNIV ZUERICH PROREKTORAT MNW ,  ENG KYNAN ,  PYK PAWEL ,  CHEVRIER EDITH ,  HOLPER LISA ,  KIPER DANIEL

Inventor： ENG KYNAN ,  PYK PAWEL ,  CHEVRIER EDITH ,  HOLPER LISA ,  KIPER DANIEL

IPC: A61F13/06 ,  A61F4/00 ,  G06F3/01

CPC classification number: A63F13/212 ,  A61F4/00 ,  A63F13/06 ,  A63F13/211 ,  A63F13/218 ,  A63F13/235 ,  A63F13/24 ,  A63F2300/1012 ,  G06F3/011 ,  G06F3/017

Abstract: Disclosed are virtual reality systems, in particular immersive virtual reality systems, their parts, construction and use. The systems and/or parts thereof may be used by adults or children, and may be adapted to support, often within a single device, a large range of users of different sizes and medical condition. Users with physical disabilities have difficulties using existing immersive technologies such as those using accessories like head-mounted displays and data gloves. Such users are provided with immersive virtual reality outputs that allow them to see virtual representations of their body parts which appear in a correct spatial position relative to the users' viewpoint.

Abstract translation: 公开了虚拟现实系统，特别是沉浸式虚拟现实系统，其部件，构造和使用。 系统和/或其部件可以由成人或儿童使用，并且可以适于通常在单个装置内支持具有不同尺寸和医疗状况的大范围用户。 身体残疾的用户难以使用现有的身临其境的技术，例如使用头戴式显示器和数据手套等附件。 为这些用户提供身临其境的虚拟现实输出，使他们能够看到他们身体部位的虚拟表示，这些虚拟表示出现在相对于用户视点的正确空间位置上。