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公开(公告)号：WO2022203932A1
公开(公告)日：2022-09-29
申请号：PCT/US2022/020727
申请日：2022-03-17
摘要： A raw meal for a cement clincker, a cement clincker made from that raw meal and a process for producing a cement clincker are provided. The clincker contains mainly the hydraulically activate alpha'H-belite polymorph and calcium sulfoaluminate (ye'elimite or C4A3Ś), at the low firing temperature of 1050°C, using a combination of fluoride and boron oxide.
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2.发明申请
公开(公告)号：WO2022187648A1
公开(公告)日：2022-09-09
申请号：PCT/US2022/018941
申请日：2022-03-04
摘要： The presently-disclosed subject matter tri-coordinate Au(I) complexes, and methods of using tri-coordinate Au(I) complexes for selectively disrupting mitochondrial structure of target cancer cells.
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公开(公告)号：WO2022140411A1
公开(公告)日：2022-06-30
申请号：PCT/US2021/064647
申请日：2021-12-21
发明人： ZHAN, Chang-Guo , ZHENG, Fang
摘要： The presently disclosed subject matter describes methods of treating cocaine use disorder and organophosphorus toxicity in which a butyrylcholinesterase fusion protein is administered to a subject in need thereof.
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公开(公告)号：WO2022005974A1
公开(公告)日：2022-01-06
申请号：PCT/US2021/039379
申请日：2021-06-28
发明人： ANEJA, Arun , DEVEZA, Lorenzo , SRINATH, Arjun , ABBENHAUS, Eric
IPC分类号： A61B17/72 , A61B17/68 , A61F2/42 , A61F2/4202 , A61F2002/30622
摘要： A method for fusing a tibiotalar joint of a patient with an intramedullary device while leaving an adjacent subtalar joint intact includes the steps of placing an intramedullary nail through a talus and into a tibia of the patient without violating a posterior facet of the adjacent subtalar joint and fixing the intramedullary nail to the talus and the tibia.
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5.发明申请
公开(公告)号：WO2021247720A1
公开(公告)日：2021-12-09
申请号：PCT/US2021/035470
申请日：2021-06-02
发明人： BHATTACHARYYA, Dibakar , HASTINGS, J., Todd , DZIUBLA, Thomas , WEI, Yinan , MILLS, Rollie , VOGLER, R.J. , BERNARD, Matthew , CONCOLINO, Jacob
IPC分类号： A41D31/30 , B32B27/12 , A41D13/1192
摘要： An antiviral mask and antiviral filter include a thin breathable, microporous polymeric membrane. That membrane may include a plurality of pores functionalized with a proteolytic enzyme, an antibody or a combination thereof. The antiviral mask and antiviral filter may also include a coating of graphene oxide, lignin sulfonate or a combination thereof and/or a fluorescent virus tagging agent.
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公开(公告)号：WO2021159089A1
公开(公告)日：2021-08-12
申请号：PCT/US2021/017109
申请日：2021-02-08
发明人： WERNER, Joshua M.
摘要： A method for recovering metals from waste materials includes steps of contacting a waste material feed stream with a first lixiviant adapted to leach copper and other base metals from the waste material feed stream and provide a treated waste material feed stream, recovering copper metal from the first lixiviant, contacting the treated waste material stream with a second lixiviant adapted to leach noble metals from the treated waste material feed stream and recovering gold from the second lixiviant.
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公开(公告)号：WO2021146327A1
公开(公告)日：2021-07-22
申请号：PCT/US2021/013293
申请日：2021-01-13
发明人： GORDON, Scott
IPC分类号： A61P1/16 , C07K14/47 , C12N15/113
摘要： Methods of treating hepatic steatosis involve administering to a subject a DENND5B inhibitor, thereby reducing the expression of and/or activity of DENND5B in liver of the subject. The DENND5B inhibitor can include antisense oligonucleotide (ASO), CRISPR interference (CRISPRi), miRNA, siRNA, locked nucleic acid (LNA) nucleotides, or a combination thereof.
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公开(公告)号：WO2021137935A2
公开(公告)日：2021-07-08
申请号：PCT/US2020/058922
申请日：2020-11-04
IPC分类号： A61K31/45 , A61P35/00 , A61K31/445
摘要： A composition and method for treating tumor cells are provided. The composition includes at least one ebastine derivative having a structure according to Formula I. The method include administering, to a patient in need thereof, an effective amount of the composition including at least one ebastine derivative having the structure according to Formula I.
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公开(公告)号：WO2021102279A1
公开(公告)日：2021-05-27
申请号：PCT/US2020/061537
申请日：2020-11-20
发明人： YANG, Chengfeng , WANG, Zhishan , LI, Yunfei
摘要： Treatments for cancer include miriplatin assembled into an ultrasmall dot (uPtD) and/or lomitapide or a pharmaceutically-acceptable salt thereof. The uPtD and/or lomitapide can be encapsulated in a nanoparticle for administration to a subject. Some embodiments further include paclitaxel or a pharmaceutically-acceptable salt thereof.
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公开(公告)号：WO2021067590A1
公开(公告)日：2021-04-08
申请号：PCT/US2020/053787
申请日：2020-10-01
发明人： DESPA, Florin
摘要： The presently-disclosed subject matter generally relates to methods for treating a subject with Alzheimer's Disease, microhemorrhages, and neurological deficits. The presently-disclosed subject matter also relates to methods for treating a subject with Alzheimer's Disease, microhemorrhages, and neurological deficits with a composition that increases epoxyeicosatrienoic acids. The presently-disclosed subject matter further relates to a method of treating or preventing Alzheimer's Disease comprising administering an agent that increases vascular LRP1 expression.
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