公开(公告)号：WO2004044561A1

公开(公告)日：2004-05-27

申请号：PCT/AU2003/001492

申请日：2003-11-11

Applicant: VARIAN AUSTRALIA PTY LTD ,  BLAIR, Robert, William

Inventor： BLAIR, Robert, William

IPC: G01N21/05

CPC classification number: G01N21/05 ,  G01N30/74 ,  G01N2021/0346

Abstract: A flow through cell (100) for use in a spectrophotometer for analysis of dissolved chemical substances in a flowing liquid stream is made up of at least an intermediate body member (114) located between two other body members (112, 116). The body members are of regular shape, for example rectangular parallelepiped and are clamped together, for example by machine screws (134, 136). Thus the cell is relatively easily manufacturable. The clamped together body members define a flow through passage which includes a hole (118) through the intermediate body member (114) and a liquid inlet region at one end of the hole and a liquid outlet region at the other end of the hole, which regions may be provided by galleries (150, 152) in sealing gaskets (130, 132) between the body members. The two other body members each include an optically transparent window (142, 146) at an end of the hole (118) thereby providing an optical pathway (A, A') through part of the flow through passage. The liquid inlet and outlet regions at the ends of hole (118) are such that the liquid flow on entering and leaving the optical pathway (A, A') occurs adjacent the optical windows transversely of the flow along the optical pathway. Thus the liquid flow sweeps across the optical windows (142, 146) and flushes the hole (118) of the optical pathway by successive increments of the liquid with minimal mixing.

Abstract translation: 用于分光光度计中用于分析流动液体流中的溶解化学物质的流通池（100）由位于两个其它身体构件（112,116）之间的至少一个中间体构件（114）构成。 身体构件具有规则形状，例如长方体并且被夹紧在一起，例如通过机械螺钉（134,136）。 因此，电池相对容易制造。 夹紧在一起的本体构件限定了一个通过通道的流动通道，该通道包括通过中间本体构件（114）的孔（118）和孔的一端处的液体入口区域和在孔的另一端的液体出口区域 区域可以由位于主体构件之间的密封垫圈（130,132）中的画廊（150,152）提供。 两个其他主体部件各自包括在孔（118）的端部处的光学透明窗（142,146），从而通过部分流动通道提供光学路径（A，A'）。 在孔（118）的端部处的液体入口和出口区域使得进入和离开光学路径（A，A'）的液体流沿着光学路径横向于流动的光学窗口发生。 因此，液体流动扫过光学窗口（142,146），并且以最小的混合以液体的连续增量冲洗光学通道的孔（118）。

公开(公告)号：WO2002086944A1

公开(公告)日：2002-10-31

申请号：PCT/AU2002/000384

申请日：2002-03-28

Applicant: VARIAN AUSTRALIA PTY LTD ,  GREGORY, Robert, Paul

Inventor： GREGORY, Robert, Paul

IPC: H01J43/30

CPC classification number: H01J43/30

Abstract: An electron multiplier (12) having a voltage divider circuit (10) for applying predetermined voltages to the dynodes (14-28) of the electron multiplier (12). One of the dynodes (18) is for attenuating an output of the electron multiplier. The voltage divider circuit (10) is made up of two networks, the first of which is a normal resistor chain (32-46) which is connected to the dynodes except the attenuating dynode (18) for applying predetermined biasing voltages to those dynodes. The second network is also made up of resistances (50, 52, 54) and applies an attenuating voltage to the attenuating dynode (18). It furthermore includes a switch (58) which is operative to vary the resistance in the second network by a discrete amount to thereby vary the attenuating voltage in a discrete step. The first network is connected between an extra-high tension voltage (EHT) supply (48) and earth (49) and the second network Is connected between the voltage supply (48) and a second voltage supply (56) which is connected to the dynode (20) following the attenuating dynode (18) for controlling the gain of the following multiplier stages. The use of two voltage sources (48, 56) ensures that the attenuation voltage is variable in discrete steps independently of the pre-determined biasing voltages applied to the remaining dynodes.

Abstract translation: 具有用于向电子倍增器（12）的倍增电极（14-28）施加预定电压的分压器电路（10）的电子倍增器（12）。 倍增电极（18）中的一个用于衰减电子倍增器的输出。 分压器电路（10）由两个网络组成，其中第一个是正常电阻器链（32-46），其连接到除衰减倍增电极（18）之外的倍增电极，用于向那些倍增电极施加预定的偏置电压。 第二网络还由电阻（50,52,54）构成，并且对衰减的倍增电极（18）施加衰减电压。 它还包括开关（58），其可操作以将第二网络中的电阻改变离散量，从而在离散步骤中改变衰减电压。 第一网络连接在超高压电压（EHT）电源（48）和地线（49）之间，第二网络连接在电源（48）和第二电源（56）之间，第二电源 在衰减倍增电极（18）之后的倍增电极（20）用于控制以下乘法器级的增益。 使用两个电压源（48,56）确保衰减电压在离散步长中是可变的，而与施加到剩余倍增电极的预定偏置电压无关。

公开(公告)号：WO2005034169A1

公开(公告)日：2005-04-14

申请号：PCT/AU2004/001357

申请日：2004-10-06

Applicant: VARIAN AUSTRALIA PTY LTD ,  KALINITCHENKO, Iouri

Inventor： KALINITCHENKO, Iouri

IPC: H01J49/26

CPC classification number: H01J49/4215 ,  H01J49/063

Abstract: An electrode for use in a reduced pressure region in a mass spectrometer whereby the electrode is subject to deposition of dielectric (non-conducting) substances thereon, which can cause unstable performance of the mass spectrometer. The surface portion of the electrode that is for providing an equipotential boundary of an electric field for influencing charged particles is made rough, in contrast to the prior art of providing a polished surface. The rough surface provides projections and cavities, which may have a regular or irregular occurrence, which it has been found significantly reduces the deposition of dielectric substances from the charged particles thereon. A preferred structure is for a rod electrode (42) to have a screw thread (44) formed thereon whereby the thread crests (43) along the rod electrode provide projections (43) and the thread roots (45) provide cavities.

Abstract translation: 用于质谱仪中的减压区域的电极，由此电极在其上沉积介电（非导电）物质，这可能导致质谱仪的不稳定性能。 与提供抛光表面的现有技术相反，用于提供用于影响带电粒子的电场的等电势边界的电极的表面部分是粗糙的。 粗糙表面提供可能具有规则或不规则发生的突起和空腔，已经发现它们显着地减少了介电物质从其上的带电粒子的沉积。 优选的结构是用于杆形电极（42）具有形成在其上的螺纹（44），由此沿杆电极的螺纹孔（43）提供突起（43），螺纹根部（45）提供空腔。

公开(公告)号：WO2004070330A1

公开(公告)日：2004-08-19

申请号：PCT/AU2004/000145

申请日：2004-02-10

Applicant: VARIAN AUSTRALIA PTY LTD ,  COMERFORD, Jeffrey, John ,  WISEMAN, Alan, Geoffrey

Inventor： COMERFORD, Jeffrey, John ,  WISEMAN, Alan, Geoffrey

IPC: G01J3/18

CPC classification number: G01J3/4406 ,  G01J3/14 ,  G01J3/18

Abstract: A monochromator (20) for use in a spectrophotometer, and a spectrophotometer, in which the provision of substantially monochromatic light for absorption or fluorescence measurements is provided by a dispersive means of the monochromator (for example a diffraction grating (34) or prism), or by an alternative wavelength selecting element such as an optical bandpass filter of the spectrophotometer, without altering the geometry of the optical path. This is enabled by the dispersive means (34) of the monochromator (20) being associated with (for example by back-to-back mounting) a non-dispersive means such as a plane mirror (36) whereby the non-dispersive means (36) is positionable in place of the dispersive means (34) by, for example, a rotational drive means (40-38). This allows for light (46) entering the monochromator (20) through entrance slit (22) to be transmitted therethrough to exit slit (32) without dispersion and without altering the geometry of the optical path. The choice of use of different dispersion means of a spectrophotometer without altering the optical path allows for optimation of the spectrophotometer for a wide range of analytical applications.

Abstract translation: 用于分光光度计的单色仪（20）和分光光度计，其中通过单色仪（例如衍射光栅（34）或棱镜）的色散装置提供用于吸收或荧光测量的基本单色光， 或通过分光光度计的光学带通滤波器等替代波长选择元件，而不改变光路的几何形状。 这是通过单色器（20）的分散装置（34）与诸如平面镜（36）之类的非分散装置（例如通过背对背安装）相关联的，从而使非分散装置 36）可以通过例如旋转驱动装置（40-38）来代替分散装置（34）。 这允许通过入口狭缝（22）进入单色仪（20）的光（46）通过其传送到出口狭缝（32）而不分散，而不改变光路的几何形状。 在不改变光学路径的情况下选择使用分光光度计的不同色散装置允许分光光度计优化用于广泛的分析应用。

公开(公告)号：WO2003098980A1

公开(公告)日：2003-11-27

申请号：PCT/AU2003/000615

申请日：2003-05-21

Applicant: VARIAN AUSTRALIA PTY LTD ,  HAMMER, Michael, Ron

Inventor： HAMMER, Michael, Ron

IPC: H05H1/34

CPC classification number: G01N21/73 ,  G01N22/00 ,  G01N33/18 ,  H05H1/0031 ,  H05H1/30 ,  H05H1/3405 ,  H05H1/42

Abstract: A Plasma torch (10) for microwave induced plasma spectrochemical analysis of a sample includes a nozzle (30) in an inlet (18) for the main plasma gas flow between outer tube (12) and intermediate tube (14) of the torch (10). The nozzle (30) increases the gas flow velocity in the sheathing gas layer for the plasma which is provided by the gas flow from the annular gap (22) between the tubes (12 and 14). The increased velocity of the gas in the sheathing gas layer "stiffens" that layer and thus better confines the microwave induced plasma (such better confinement not being necessary for an ICP torch). Thus the torch is of improved durability for a microwave induced plasma compared to an ICP torch. The sample injection (inner) tube (16) may have a reduced diameter outlet at its end (34) which is substantially level with the end (35) of intermediate tube (14) to improve injection of a sample into the microwave induced plasma. The inlet end (26) of the sample injection tube (16) may include a heater (36) to assist in preventing blockages in tube (16) near its outlet end.

Abstract translation: 用于样品的微波诱导等离子体光谱化学分析的等离子体手电筒（10）包括在用于主管等离子体气体流动的入口（18）中的喷嘴（30），用于在外管（12）和火炬（10）的中间管（14）之间 ）。 喷嘴（30）增加了由来自管（12和14）之间的环形间隙（22）的气流提供的等离子体的护套气层中的气体流速。 护层气体层中气体的增加速度“加固”该层，从而更好地限制了微波诱导的等离子体（这种更好的限制对于ICP焊炬来说不是必需的）。 因此，与ICP焊枪相比，手电筒具有改善的微波感应等离子体的耐久性。 样品注入（内）管（16）可以在其端部（34）处具有减小直径的出口，该出口基本上与中间管（14）的端部（35）平齐，以改进将样品注入到微波感应等离子体中。 样品注入管（16）的入口端（26）可以包括加热器（36），以帮助防止在其出口端附近的管（16）中的堵塞。

公开(公告)号：WO2007134363A1

公开(公告)日：2007-11-29

申请号：PCT/AU2007/000610

申请日：2007-05-09

Applicant: VARIAN AUSTRALIA PTY LTD ,  HOSEMANS, Steven, William

Inventor： HOSEMANS, Steven, William

IPC: H01J49/40 ,  H01J7/24

CPC classification number: H01J49/105 ,  H05H1/30

Abstract: An RF power generator (10) for an induction coil (26) for exciting an inductively coupled plasma in a torch (27) for spectrometry. The generator (10) comprises a switching circuit (12) for alternately switching ON and OFF solid state switching devices (20) via gate drive voltages (22) for supplying RF power into a resonant load circuit (16) comprising the induction coil (26) and parallel connected capacitance (25). The gate drive circuits (24) for each solid state switching device (20) each include a portion (30) that is mutually inductively coupled with leads of the induction coil (26) to provide the gate drive voltages (22). The circuit allows for reduced componentry and therefore a relatively inexpensive RF power generator for exciting and sustaining an inductively coupled plasma for spectrometry.

Abstract translation: 一种用于感应线圈（26）的RF功率发生器（10），用于激发用于光谱测量的手电筒（27）中的感应耦合等离子体。 发电机（10）包括用于经由用于将RF功率提供到包括感应线圈（26）的谐振负载电路（16）的栅极驱动电压（22）交替地接通和断开固态开关装置（20）的开关电路（12） ）和并联连接电容（25）。 每个固态开关装置（20）的栅极驱动电路（24）各自包括与感应线圈（26）的引线相互感应耦合以提供栅极驱动电压（22）的部分（30）。 该电路允许减少的组件，因此用于激发和维持用于光谱测定的电感耦合等离子体的相对便宜的RF功率发生器。

公开(公告)号：WO2006102712A1

公开(公告)日：2006-10-05

申请号：PCT/AU2006/000423

申请日：2006-03-31

Applicant: VARIAN AUSTRALIA PTY LTD ,  HAMMER, Michael, Ron

Inventor： HAMMER, Michael, Ron

IPC: H05H1/30 ,  G01N21/73

CPC classification number: H01J49/105 ,  G01N21/68 ,  G01N21/73 ,  H05H1/30

Abstract: A spectroscopy system for spectro-chemical analysis of a sample includes a plasma torch (50) for generating a microwave induced plasma (90) as a spectroscopic source. The plasma forming gas is nitrogen which can contain an oxygen impurity. Thus the system includes a nitrogen generator (70) which is preferably supplied with compressed atmospheric air from a compressor (75) for oxygen to be removed from the air by adsorption. The invention allows the use of an on-site nitrogen gas generator and thus gives cost savings because the need to obtain supplies of bottled high purity gas is eliminated.

Abstract translation: 用于样品的光谱化学分析的光谱系统包括用于产生作为光谱源的微波诱导等离子体（90）的等离子体焰炬（50）。 等离子体形成气体是可含有氧杂质的氮。 因此，该系统包括氮气发生器（70），其优选地从压缩机（75）供应压缩的空气，用于通过吸附从空气中除去氧气。 本发明允许使用现场氮气发生器，从而节省了成本，因为消除了获得瓶装高纯气体供应的需要。

公开(公告)号：WO2003077280A1

公开(公告)日：2003-09-18

申请号：PCT/AU2003/000242

申请日：2003-02-27

Applicant: VARIAN AUSTRALIA PTY LTD ,  KALINITCHENKO, Iouri

Inventor： KALINITCHENKO, Iouri

IPC: H01J49/26

CPC classification number: H01J49/067 ,  H01J49/105

Abstract: A plasma source mass spectrometer (20) having an ion beam extraction electrode (45) associated with a skimmer cone (40) to restrict the pumping of gas from a region (60) immediately behind the skimmer cone orifice (42) to provide a higher pressure ( e.g. 1-10 -2 Torr) in the region (60) compared to the pressure downstream of the electrode (45) ( e.g. 10 -3 -10 -4 Torr). This provides a collisional gas volume (60) for plasma (28) for attenuating polyatomic and multicharged interfering ions prior to extraction of an ion beam (49). In one embodiment a substance ( e.g . hydrogen) can be supplied into the region (60) to assist attenuation of polyatomic and multicharged interfering ions by reactive or collisional interactions.

Abstract translation: 一种等离子体源质谱仪（20），其具有与分离器锥体（40）相关联的离子束引出电极（45），以限制从紧挨着分离器锥形孔口（42）的后面的区域（60）泵送气体，以提供更高的 与电极（45）下游的压力（例如10-3-10-4乇）相比，区域（60）中的压力（例如1-10-2乇）。 这提供了用于在提取离子束（49）之前衰减多原子和多电荷干扰离子的等离子体（28）的碰撞气体体积（60）。 在一个实施方案中，可以将物质（例如氢）供应到区域（60）中，以通过反应性或碰撞相互作用来辅助多原子和多电荷干扰离子的衰减。

公开(公告)号：WO2003005780A1

公开(公告)日：2003-01-16

申请号：PCT/AU2002/000386

申请日：2002-03-28

Applicant: VARIAN AUSTRALIA PTY LTD ,  WISEMAN, Alan, Geoffrey

Inventor： WISEMAN, Alan, Geoffrey

IPC: H05H1/42

CPC classification number: H01J49/105 ,  G01N21/73 ,  H05H1/30

Abstract: A torch for producing an inductively coupled or microwave induced plasma for use in spectrochemical analysis. The torch includes a central tube (25) for conveying a flow of a gas carrying sample aerosol to a plasma (17) produced in the torch. The tube (25) has an inlet (31) and an outlet (39) of smaller size than the inlet and is shaped to deliver a substantially laminar flow of the gas at the outlet (39). The tube (25) is tapered along at least a substantial portion of its length such that its cross-sectional area gradually and smoothly reduces towards its outlet (39) along at least a substantial portion of its length. It has been found that such a tapered tube is resistant to obstruction by salts deposited from samples containg high levels of dissolved solids.

Abstract translation: 用于生产用于光谱化学分析的电感耦合或微波诱导等离子体的手电筒。 手电筒包括用于将载气样品气溶胶的流传送到在割炬中产生的等离子体（17）的中心管（25）。 管（25）具有比入口小的入口（31）和出口（39），并且成形为在出口（39）处输送大致层流的气体。 管（25）沿着其长度的至少大部分是锥形的，使得其横截面面积沿其长度的至少大部分逐渐地平滑地朝向其出口（39）减小。 已经发现，这种锥形管耐受由包含高水平的溶解固体的样品沉积的盐的阻塞。

公开(公告)号：WO2006042365A1

公开(公告)日：2006-04-27

申请号：PCT/AU2005/001607

申请日：2005-10-18

Applicant: VARIAN AUSTRALIA PTY LTD ,  HAMMER, Michael

Inventor： HAMMER, Michael

IPC: G01N30/89 ,  G01N35/10

CPC classification number: G01N30/92 ,  G01N21/03 ,  G01N30/466 ,  G01N30/74 ,  G01N2021/0346 ,  G01N2030/027

Abstract: A multi-column liquid chromatography system (10) for performing a plurality of liquid chromatography separations in parallel is based on a column plate structure (12) having parallel grooves (20) formed in a surface (22) of a plate (18), a cover sheet (40) bonded to the surface (22) to cover the grooves (20) and a stationary phase (38) contained in each covered groove (20). Through holes (24, 26) in the plate (18) define respective inlets (24) for the chromatography columns (14) and flow cells (16) at outlets, with the cover sheet (40) providing an optically transparent end wall for the flow cells (16) and another cover sheet (42) bonded to the opposite surface (30) of the plate (18) providing the other optically transparent end wall for the flow cells (16). Thus merely three parts need be provided for a structure for providing the chromatography columns, that is, a plate having grooves and through holes plus two cover sheets. The chromatography system (10) additionally includes a pumping system (46) comprising a syringe pump (48) for each column (14), an optical system (28) for transmitting analytical radiation through the flow cells (16) and a fraction collection sheet (110) containing wells (112) which is fed past outlets (34-35) from the column plate structure (12).

Abstract translation: 基于在板（18）的表面（22）中形成有平行凹槽（20）的柱板结构（12），用于并行进行多个液相色谱分离的多柱液相色谱系统（10） 覆盖在所述表面（22）上以覆盖所述槽（20）的盖板（40）和包含在每个所述覆盖槽（20）中的固定相（38）。 板（18）中的通孔（24,26）在出口处限定用于色谱柱（14）和流动池（16）的相应入口（24），其中覆盖片（40）提供光学透明的端壁，用于 流动池（16）和另一个覆盖板（42），其结合到板（18）的相对表面（30），为该流动池（16）提供另一个光学透明的端壁。 因此，仅需要提供用于提供色谱柱的结构的三个部分，即，具有凹槽和通孔加上两个覆盖片的板。 色谱系统（10）还包括泵系统（46），其包括用于每列（14）的注射泵（48），用于将分析辐射传送通过流动池（16）的光学系统（28） （110），其包含从所述塔板结构（12）经过出口（34-35）馈送的孔（112）。