METHOD AND APPARATUS FOR ANALYZING HYBRIDIZED BIOCHIP PATTERNS USING RESONANCE INTERACTIONS
    1.
    发明申请
    METHOD AND APPARATUS FOR ANALYZING HYBRIDIZED BIOCHIP PATTERNS USING RESONANCE INTERACTIONS 审中-公开
    使用共振相互作用分析混合生物模式的方法和装置

    公开(公告)号:WO0052625A2

    公开(公告)日:2000-09-08

    申请号:PCT/US0004076

    申请日:2000-02-17

    Inventor: GULATI SANDEEP

    CPC classification number: B82Y5/00 B82Y10/00 G06F19/20 G06F19/24

    Abstract: A technique is described for identifying mutations, if any, present in a biological sample, from a pre-selected set of known mutations. The method can be applied to DNA, RNA and peptide nucleic acid (PNA) microarrays. The method analyzes a dot spectrogram representative of quantized hybridization activity of oligonucleotides in the sample to identify the mutations. In accordance with the method, a resonance pattern is generated which is representative of nonlinear resonances between a stimulus pattern associated with the set of known mutations and the dot spectrogram. The resonance pattern is interpreted to a yield a set of confirmed mutations by comparing resonances found therein with predetermined resonances expected for the selected set of mutations. In a particular example, the resonance pattern is generated by iteratively processing the dot spectrogram by performing a convergent reverberation to yield a resonance pattern representative of resonances between a predetermined set of selected Quantum Expressor Functions and the dot spectrogram until a predetermined degree of convergence is achieved between the resonances found in the resonance pattern and resonances expected for the set of mutations. The resonance pattern is analyzed to a yield a set of confirmed mutations by mapping the confirmed mutations to known diseases associated with the pre-selected set of known mutations to identify diseases, if any, indicated by the biological sample. By exploiting a resonant interaction, mutation signatures may be robustly identified even in circumstances involving low signal to noise ratios or, in some cases, negative signal to noise ratios.

    Abstract translation: 描述了从预先选定的一组已知突变中鉴定存在于生物样品中的突变(如果有的话)的技术。 该方法可应用于DNA,RNA和肽核酸(PNA)微阵列。 该方法分析了代表样品中寡核苷酸的量化杂交活性的点光谱图,以鉴定突变。 根据该方法,产生表示与已知突变集相关联的刺激图案与点谱图之间的非线性共振的共振图案。 将共振模式解释为通过将其中发现的共振与所选择的突变组所预期的预定共振进行比较来产生一组确认的突变。 在特定示例中,通过迭代地处理点谱图来生成谐振图案,通过执行收敛混响以产生表示预定的选定量子表达函数集合与点谱图之间的谐振的共振图案,直到达到预定的收敛度 在谐振模式中发现的共振和对于该组突变所预期的共振之间。 通过将确认的突变映射到与预先选择的一组已知突变相关的已知疾病以鉴定由生物样品指示的疾病(如果有的话)),分析共振模式以产生一组确认的突变。 通过利用共振相互作用,即使在涉及低信噪比的情况下,或者在某些情况下,信号与信噪比也是相反的,突变特征也可以被鲁棒识别。

    SOFTWARE ENABLED VIDEO AND SENSOR INTEROPERABILITY SYSTEM AND METHOD
    3.
    发明申请
    SOFTWARE ENABLED VIDEO AND SENSOR INTEROPERABILITY SYSTEM AND METHOD 审中-公开
    软件启用视频和传感器互操作性系统和方法

    公开(公告)号:WO2007117705A9

    公开(公告)日:2008-07-10

    申请号:PCT/US2007008918

    申请日:2007-04-09

    Abstract: A novel method and software system design are presented for interchanging sensors from different vendors in a plug and play manner to drive mission critical applications within a sensor based architecture, policy based framework, event-based architecture. This technique is applicable to sensors directly attached to a computer, or sensors attached to a network, or sensors attached to a controller node which is attached to a network or directly attached to a computer.

    Abstract translation: 提出了一种新颖的方法和软件系统设计,用于以即插即用的方式交换来自不同供应商的传感器,以在基于传感器的架构,基于策略的框架,基于事件的架构中驱动任务关键应用。 该技术适用于直接连接到计算机的传感器,或连接到网络的传感器,或连接到连接到网络或直接连接到计算机的控制器节点的传感器。

    ACTIVE INTERFEROMETRIC SIGNAL ANALYSIS IN SOFTWARE
    4.
    发明申请
    ACTIVE INTERFEROMETRIC SIGNAL ANALYSIS IN SOFTWARE 审中-公开
    软件中的主动干涉信号分析

    公开(公告)号:WO2004102456A3

    公开(公告)日:2005-01-27

    申请号:PCT/US0321525

    申请日:2003-07-09

    Inventor: GULATI SANDEEP

    CPC classification number: G06F19/20

    Abstract: Techniques are provided for performing active interferometric signal analysis in software. The techniques exploit expressor functions designed to extract spectral invariants of events of interest associated with an arrayed platform device used to detect the signal pattern to be analyzed. Various techniques for generating expressor functions are also provided. Depending upon the implementation, the techniques provide for both detection and quantitation analysis by exploiting either constructive or destructive interferometric analysis using reverberant convergence to detect resonance events. The techniques achieve software emulation of wave-particle interactions and wave-wave interactions and can operate in either the frequency domain or the phase domain. The techniques may be used for analyzing static spatial systems, static data from arrayed measurement platforms, dynamical systems, spatio-temporal systems or plasma systems.

    Abstract translation: 提供了用于在软件中执行主动干涉信号分析的技术。 该技术利用设计用于提取与用于检测要分析的信号模式的阵列平台装置相关联的感兴趣事件的光谱不变性的表达式功能。 还提供了用于生成表现功能的各种技术。 根据实施情况,这些技术通过利用混响收敛来进行建设性或破坏性干涉分析来检测共振事件,从而提供检测和定量分析。 该技术实现了波粒相互作用和波浪相互作用的软件仿真,并且可以在频域或相域中操作。 这些技术可用于分析静态空间系统,来自阵列测量平台的静态数据,动力系统,时空系统或等离子体系统。

    DETECTING EVENTS OF INTEREST USING QUANTUM RESONANCE INTERFEROMETRY
    9.
    发明申请
    DETECTING EVENTS OF INTEREST USING QUANTUM RESONANCE INTERFEROMETRY 审中-公开
    使用量子共振干涉法检测利益事件

    公开(公告)号:WO2006130165A2

    公开(公告)日:2006-12-07

    申请号:PCT/US2005/031382

    申请日:2005-09-02

    Inventor: GULATI, Sandeep

    Abstract: Incoming data from, for example, an array of detectors, may be received. A dynamical system may be initialized corresponding to a modality of the incoming data so that a measurement probe based on the initialized dynamical system may be generated. Such a measurement probe may be injected into a quantum mechanical system so that it may be determined whether the injection of the measurement probe into the quantum mechanical system results in a collapse of the quantum mechanical system. Thereafter, it may be determined that a signal is present within the incoming data if the quantum mechanical system collapses. Related methods, apparatuses, systems, and computer-program products are also described.

    Abstract translation: 可以接收来自例如检测器阵列的传入数据。 可以根据输入数据的模态对动态系统进行初始化,从而可以生成基于初始化的动力系统的测量探针。 可以将这样的测量探针注入到量子力学系统中,从而可以确定将测量探针注入量子力学系统是否导致量子力学系统的崩溃。 此后,如果量子力学系统崩溃,则可以确定在输入数据内存在信号。 还描述了相关方法,装置,系统和计算机程序产品。

    ACTIVE INTERFEROMETRIC SIGNAL ANALYSIS IN SOFTWARE
    10.
    发明申请
    ACTIVE INTERFEROMETRIC SIGNAL ANALYSIS IN SOFTWARE 审中-公开
    软件中的主动干涉信号分析

    公开(公告)号:WO2004102456A2

    公开(公告)日:2004-11-25

    申请号:PCT/US2003/021525

    申请日:2003-07-09

    Inventor: GULATI, Sandeep

    CPC classification number: G06F19/20

    Abstract: Techniques are provided for performing active interferometric signal analysis in software. The techniques exploit expressor functions designed to extract spectral invariants of events of interest associated with an arrayed platform device used to detect the signal pattern to be analyzed. Various techniques for generating expressor functions are also provided. Depending upon the implementation, the techniques provide for both detection and quantitation analysis by exploiting either constructive or destructive interferometric analysis using reverberant convergence to detect resonance events. The techniques achieve software emulation of wave-particle interactions and wave-wave interactions and can operate in either the frequency domain or the phase domain. The techniques may be used for analyzing static spatial systems, static data from arrayed measurement platforms, dynamical systems, spatio-temporal systems or plasma systems.

    Abstract translation: 提供了用于在软件中执行主动干涉信号分析的技术。 该技术利用设计用于提取与用于检测要分析的信号模式的阵列平台装置相关联的感兴趣事件的光谱不变性的表达式功能。 还提供了用于生成表现功能的各种技术。 根据实施情况,这些技术通过利用混响收敛来进行建设性或破坏性干涉分析来检测共振事件,从而提供检测和定量分析。 该技术实现了波粒相互作用和波浪相互作用的软件仿真,并且可以在频域或相域中操作。 这些技术可用于分析静态空间系统,来自阵列测量平台的静态数据,动力系统,时空系统或等离子体系统。

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