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1.发明申请METHODS OF IDENTIFYING REDUCED INTERNALIZATION TRANSMEMBRANE RECEPTOR AGONISTS 审中-公开鉴定减少内源性转录组受体激动剂的方法
公开(公告)号：WO2004038005A2
公开(公告)日：2004-05-06
申请号：PCT/US2003/033961
申请日：2003-10-24
Applicant: NORAK BIOSCIENCES, INC. , LOOMIS, Carson, R. , OAKLEY, Robert, H. , WANG, Shuntai , ECKHARDT, Allen, E.
Inventor： LOOMIS, Carson, R. , OAKLEY, Robert, H. , WANG, Shuntai , ECKHARDT, Allen, E.
IPC: C12N
CPC classification number: G01N33/566 , G01N2500/04
Abstract: Described herein are methods of identifying a transmembrane receptor (TMR) agonist and compounds identified by this method. The TMR agonist (TMRA) is capable of activating TMR signaling while exhibiting reduced TMR internalization over a control compound.
Abstract translation: 本文描述了鉴定跨膜受体（TMR）激动剂和通过该方法鉴定的化合物的方法。 TMR激动剂（TMRA）能够激活TMR信号，同时在对照化合物上显示降低的TMR内化。
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2.发明申请METHODS OF IDENTIFYING REDUCED INTERNALIZATION TRANSMEMBRANE RECEPTOR AGONISTS 审中-公开鉴定减少内源性转录组受体激动剂的方法
公开(公告)号：WO2004038005A3
公开(公告)日：2005-02-03
申请号：PCT/US0333961
申请日：2003-10-24
Applicant: NORAK BIOSCIENCES INC , LOOMIS CARSON R , OAKLEY ROBERT H , WANG SHUNTAI , ECKHARDT ALLEN E
Inventor： LOOMIS CARSON R , OAKLEY ROBERT H , WANG SHUNTAI , ECKHARDT ALLEN E
IPC: C12N20060101 , G01N33/53 , G01N33/566 , G01N33/567
CPC classification number: G01N33/566 , G01N2500/04
Abstract: Described herein are methods of identifying a transmembrane receptor (TMR) agonist and compounds identified by this method. The TMR agonist (TMRA) is capable of activating TMR signaling while exhibiting reduced TMR internalization over a control compound.
Abstract translation: 本文描述了鉴定跨膜受体（TMR）激动剂和通过该方法鉴定的化合物的方法。 TMR激动剂（TMRA）能够激活TMR信号，同时在对照化合物上显示降低的TMR内化。
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