公开(公告)号：WO2007002325A1

公开(公告)日：2007-01-04

申请号：PCT/US2006/024361

申请日：2006-06-21

Applicant: PLEXXIKON, INC. ,  IBRAHIM, Prahbha, N. ,  ARTIS, Dean, R. ,  BREMER, Ryan ,  MAMO, Shumeye ,  NESPI, Marika ,  ZHANG, Chao ,  ZHANG, Jiazhong ,  ZHU, Yong-Liang ,  TSAI, James ,  HIRTH, Klaus-Peter ,  BOLLAG, Gideon ,  SPEVAK, Wayne ,  CHO, Hanna ,  GILLETTE, Samuel, J. ,  WU, Guoxiam ,  ZHU, Hongyao ,  SHI, Shenghua

Inventor： IBRAHIM, Prahbha, N. ,  ARTIS, Dean, R. ,  BREMER, Ryan ,  MAMO, Shumeye ,  NESPI, Marika ,  ZHANG, Chao ,  ZHANG, Jiazhong ,  ZHU, Yong-Liang ,  TSAI, James ,  HIRTH, Klaus-Peter ,  BOLLAG, Gideon ,  SPEVAK, Wayne ,  CHO, Hanna ,  GILLETTE, Samuel, J. ,  WU, Guoxiam ,  ZHU, Hongyao ,  SHI, Shenghua

IPC: C07D471/04 ,  A61K31/435 ,  C07C49/517 ,  A61P35/00

CPC classification number: C07D471/04 ,  A61K31/437 ,  A61K31/496 ,  A61K31/5377 ,  C07C37/62 ,  C07C39/27 ,  C07C45/00 ,  C07C45/673 ,  C07C45/71 ,  C07C47/565 ,  C07C47/575 ,  C07D209/08

Abstract: Compounds of formula III which are active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Abstract translation: 描述了对蛋白激酶有活性的式III化合物，以及使用这些化合物治疗与蛋白激酶异常活性相关的疾病和病症的方法。