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    DIAGNOSIS OF AUTISM SPECTRUM DISORDER BY MULTIOMICS PLATFORM
    3.
    发明申请
    DIAGNOSIS OF AUTISM SPECTRUM DISORDER BY MULTIOMICS PLATFORM 审中-公开

    公开(公告)号：WO2022249182A2

    公开(公告)日：2022-12-01

    申请号：PCT/IL2022/050555

    申请日：2022-05-25

    Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.

    Inventor： AMAL, Haitham

    IPC: G01N33/68 ,  G01N33/497 ,  G16H50/70 ,  G01N2440/14 ,  G01N2440/26 ,  G01N33/6896 ,  G16B25/10 ,  G16H50/20

    Abstract: The present invention is directed to methods for determining an autism spectrum condition in a subject. The methods comprise determining in a sample obtained from the subject any one of: (i) an elevated expression level of at least one biomarker selected from Table 2; (ii) a reduced expression level of at least one biomarker selected from Table 3; (iii) phosphorylation of at least one biomarker selected from Table 4; (iv) S-nitrosylation (SNO) of at least one biomarker selected from Table 5; (v) a volatile organic compound (VOC) profile comprising at least one VOC selected from any one of Table la, Table lb, Table lc, Table Id, Table le, (vi) any combination of (i) to (v), wherein a significant change of the at least one biomarker in said sample compared to control, is indicative of the subject being afflicted with an autism spectrum condition. Further provided is a kit suitable for determining an autism spectrum condition.

    SYSTEMS AND METHODS TO ACQUIRE THREE DIMENSIONAL IMAGES USING SPECTRAL INFORMATION
    5.
    发明申请
    SYSTEMS AND METHODS TO ACQUIRE THREE DIMENSIONAL IMAGES USING SPECTRAL INFORMATION 审中-公开

    公开(公告)号：WO2022234588A1

    公开(公告)日：2022-11-10

    申请号：PCT/IL2022/050719

    申请日：2022-07-05

    Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.

    Inventor： LEVY, Uriel ,  EDREI, Eitan

    IPC: G01B11/24 ,  A61B5/00 ,  G02B21/00

    Abstract: The disclosure relates to the technique, including systems and methods, for use in optical topographical and/or tomographic 3D imaging of a sample. The system may include (a) a lens unit, chromatically dispersive so that its focal length varies depending on a light wavelength, the lens unit being configured to pass therethrough polychromatic light arriving from and originated at a sample, while selectively collimating those spectral components of the polychromatic light which are in focus based on their wavelengths and origins; and (b) an etalon structure accommodated in an optical path of light being output from the lens unit to receive the collimated light, said etalon structure being configured to operate with multiple resonant wavelengths and to provide respective spectral transmittance peaks at said resonant wavelengths.

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