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公开(公告)号：WO2008061020A2
公开(公告)日：2008-05-22
申请号：PCT/US2007084293
申请日：2007-11-09
Applicant: NOVARTIS AG , LAI ALBERT , YU GUOYING K
Inventor： LAI ALBERT , YU GUOYING K
IPC: C07K16/28 , A61K47/48 , A61K51/10 , A61P35/00 , C12N15/113 , C12Q1/68 , G01N33/574 , G01N33/68
CPC classification number: C07K16/2896 , C07K16/30 , C07K2317/77 , C12N15/1138 , C12N2310/14 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/178 , G01N33/57484 , G01N2333/726 , G01N2500/02
Abstract: The invention provides, inter alia, methods for treating cancer, compositions for treating cancer, and methods and compositions for diagnosing and/or detecting cancer. In particular, the present invention provides compositions and methods for treating, diagnosing and detecting cancers associated with FZDlO overexpression.
Abstract translation: 本发明尤其提供了用于治疗癌症的方法，用于治疗癌症的组合物，以及用于诊断和/或检测癌症的方法和组合物。 具体而言，本发明提供了用于治疗，诊断和检测与FZD10过度表达相关的癌症的组合物和方法。
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公开(公告)号：WO2007120787A2
公开(公告)日：2007-10-25
申请号：PCT/US2007/009063
申请日：2007-04-12
Applicant: NOVARTIS VACCINES & DIAGNOSTICS, INC. , JANTAPOUR, Mary J. , YU, Guoying , TO, Robert , CHAN, Vivien , ZIMMERMAN, Deborah
Inventor： JANTAPOUR, Mary J. , YU, Guoying , TO, Robert , CHAN, Vivien , ZIMMERMAN, Deborah
IPC: A61K45/06
CPC classification number: C07K14/4748 , C07K16/18 , C07K16/28 , C07K2317/34 , C12N15/1138 , C12N2310/11 , C12N2310/14
Abstract: The invention provides, inter alia, methods for treating cancer, compositions for treating cancer, and methods and compositions for diagnosing and/or detecting cancer. In particular, the present invention provides compositions and methods for treating, diagnosing and detecting cancers associated with LIV-1 overexpression.
Abstract translation: 本发明尤其提供了治疗癌症的方法，用于治疗癌症的组合物，以及用于诊断和/或检测癌症的方法和组合物。 特别地，本发明提供了用于治疗，诊断和检测与LIV-1过表达相关的癌症的组合物和方法。
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公开(公告)号：WO2006110594A2
公开(公告)日：2006-10-19
申请号：PCT/US2006/013174
申请日：2006-04-07
Applicant: CHIRON CORPORATION , SAGRES DISCOVERY, INC. , LAI, Albert , FANIDI, Abdallah , BOOHER, Robert N. , TSE, Christin , XU, Xie , YU, Guoying , MOLER, Edward , ROWE, Michael
Inventor： LAI, Albert , FANIDI, Abdallah , BOOHER, Robert N. , TSE, Christin , XU, Xie , YU, Guoying , MOLER, Edward , ROWE, Michael
IPC: A61P35/00 , G01N33/574 , C12Q1/68 , C12N15/11 , A61K39/00
CPC classification number: C12N15/1138 , C12N15/1135 , C12N2310/14 , C12Q1/68 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , G01N33/5748 , G01N2333/4704
Abstract: This invention is in the field of cancer-related genes. Specifically it relates to methods for detecting cancer or the likelihood of developing cancer based on the presence or absence of the SEM A4D gene or proteins encoded by this gene. The invention also provides methods and molecules for upregulating or downregulating the SEMA4D gene.
Abstract translation: 本发明涉及癌症相关基因领域。 具体地说，涉及根据存在或不存在由该基因编码的SEM A4D基因或蛋白质来检测癌症或发生癌症的可能性的方法。 本发明还提供了用于上调或下调SEMA4D基因的方法和分子。
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公开(公告)号：WO2008061020A9
公开(公告)日：2008-11-13
申请号：PCT/US2007084293
申请日：2007-11-09
Applicant: NOVARTIS AG , LAI ALBERT , YU GUOYING K
Inventor： LAI ALBERT , YU GUOYING K
IPC: G01N33/574 , A61P35/00 , C07K16/28 , C12N15/113 , C12Q1/68
CPC classification number: C07K16/2896 , C07K16/30 , C07K2317/77 , C12N15/1138 , C12N2310/14 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/178 , G01N33/57484 , G01N2333/726 , G01N2500/02
Abstract: The invention provides, inter alia, methods for treating cancer, compositions for treating cancer, and methods and compositions for diagnosing and/or detecting cancer. In particular, the present invention provides compositions and methods for treating, diagnosing and detecting cancers associated with FZDlO overexpression.
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公开(公告)号：WO2006110587A3
公开(公告)日：2006-10-19
申请号：PCT/US2006/013162
申请日：2006-04-07
Applicant: NOVARTIS VACCINES AND DIAGNOSTICS INC. , SAGRES DISCOVERY, INC. , FANIDI, Abdallah , BOOHER, Robert , TSE, Christin , XU, Xie , YU, Guoying , MOLER, Edward , ROWE, Michael
Inventor： FANIDI, Abdallah , BOOHER, Robert , TSE, Christin , XU, Xie , YU, Guoying , MOLER, Edward , ROWE, Michael
IPC: C12Q1/68
Abstract: This invention is in the field of cancer-related genes. Specifically it relates to methods for detecting cancer or the likelihood of developing cancer based on the presence or absence of the DDR2 gene or proteins encoded by this gene. The invention also provides methods and molecules for upregulating or downregulating the DDR2 gene.
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Patent Agency Ranking
公开(公告)号：WO2006110581A3
公开(公告)日：2006-10-19
申请号：PCT/US2006/013153
申请日：2006-04-07
Applicant: NOVARTIS VACCINES AND DIAGNOSTICS INC. , SAGRES DISCOVERY, INC. , LAI, Albert , FANIDI, Abdallah , BOOHER, Robert , TSE, Christin , XU, Xie , YU, Guoying , MOLER, Edward , ROWE, Michael
Inventor： LAI, Albert , FANIDI, Abdallah , BOOHER, Robert , TSE, Christin , XU, Xie , YU, Guoying , MOLER, Edward , ROWE, Michael
IPC: C12Q1/68 , G01N33/574
Abstract: This invention is in the field of cancer-associated genes. Specifically it relates to methods for detecting cancer or the likelihood of developing cancer based on the presence or absence of expression of certain genes or proteins encoded by those genes. The invention also provides methods and molecules for upregulating or downregulating these cancer-associated genes.
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公开(公告)号：WO2006110581A2
公开(公告)日：2006-10-19
申请号：PCT/US2006013153
申请日：2006-04-07
Applicant: CHIRON CORP , SAGRES DISCOVERY INC , LAI ALBERT , FANIDI ABDALLAH , BOOHER ROBERT , TSE CHRISTIN , XU XIE , YU GUOYING , MOLER EDWARD , ROWE MICHAEL
Inventor： LAI ALBERT , FANIDI ABDALLAH , BOOHER ROBERT , TSE CHRISTIN , XU XIE , YU GUOYING , MOLER EDWARD , ROWE MICHAEL
IPC: C12Q1/68 , G01N33/574
CPC classification number: C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158
Abstract: This invention is in the field of cancer-associated genes. Specifically it relates to methods for detecting cancer or the likelihood of developing cancer based on the presence or absence of expression of certain genes or proteins encoded by those genes. The invention also provides methods and molecules for upregulating or downregulating these cancer-associated genes.
Abstract translation: 本发明在癌症相关基因领域。 具体地说，涉及用于检测癌症的方法或基于这些基因编码的某些基因或蛋白质的表达的存在或不存在来发展癌症的可能性。 本发明还提供了用于上调或下调这些癌症相关基因的方法和分子。
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8.发明申请
公开(公告)号：WO2008011519A2
公开(公告)日：2008-01-24
申请号：PCT/US2007/073895
申请日：2007-07-19
Applicant: NOVARTIS AG , JANATPOUR, Mary, J. , CHAN, Vivien , YU, Guoying , FANIDI, Abdallah
Inventor： JANATPOUR, Mary, J. , CHAN, Vivien , YU, Guoying , FANIDI, Abdallah
IPC: A61K39/00
CPC classification number: C07K16/2803 , C12N15/113 , G01N33/574 , G01N2333/4703 , Y10T436/143333
Abstract: The invention provides, inter alia, methods for treating cancer, compositions for treating cancer, and methods and compositions for diagnosing and/or detecting cancer. In particular, the present invention provides compositions and methods for treating, diagnosing and detecting cancers associated with AMIGO-2 overexpression.
Abstract translation: 本发明尤其提供了治疗癌症的方法，用于治疗癌症的组合物，以及用于诊断和/或检测癌症的方法和组合物。 特别地，本发明提供了用于治疗，诊断和检测与AMIGO-2过度表达相关的癌症的组合物和方法。
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公开(公告)号：WO2006110594A3
公开(公告)日：2007-04-05
申请号：PCT/US2006013174
申请日：2006-04-07
Applicant: NOVARTIS VACCINES & DIAGNOSTIC , SAGRES DISCOVERY INC , LAI ALBERT , FANIDI ABDALLAH , BOOHER ROBERT N , TSE CHRISTIN , XU XIE , YU GUOYING , MOLER EDWARD , ROWE MICHAEL
Inventor： LAI ALBERT , FANIDI ABDALLAH , BOOHER ROBERT N , TSE CHRISTIN , XU XIE , YU GUOYING , MOLER EDWARD , ROWE MICHAEL
IPC: A61P35/00 , A61K39/00 , C12N15/113 , C12Q1/68 , G01N33/574
CPC classification number: C12N15/1138 , C12N15/1135 , C12N2310/14 , C12Q1/6802 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , G01N33/5748 , G01N2333/4704
Abstract: This invention is in the field of cancer-related genes. Specifically it relates to methods for detecting cancer or the likelihood of developing cancer based on the presence or absence of the SEM A4D gene or proteins encoded by this gene. The invention also provides methods and molecules for upregulating or downregulating the SEMA4D gene.
Abstract translation: 本发明涉及癌症相关基因领域。 具体地说，本发明涉及根据存在或不存在由该基因编码的SEM A4D基因或蛋白质来检测癌症或发展癌症的可能性的方法。 本发明还提供了用于上调或下调SEMA4D基因的方法和分子。
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公开(公告)号：WO2006110599A3
公开(公告)日：2006-10-19
申请号：PCT/US2006/013182
申请日：2006-04-07
Applicant: NOVARTIS VACCINES AND DIAGNOSTICS INC. , SAGRES DISCOVERY, INC. , YU, Guoying , MOLER, Edward , ROWE, Michael , TSE, Christin , XU, Xie
Inventor： YU, Guoying , MOLER, Edward , ROWE, Michael , TSE, Christin , XU, Xie
IPC: A61K38/17 , C12Q1/68 , G01N33/574 , G01N33/68
Abstract: This invention is in the field of cancer-related genes. Specifically it relates to methods for detecting cancer or the likelihood of developing cancer based on the presence or absence of the CACNA1E gene or proteins encoded by this gene. The invention also provides methods and molecules for upregulating or downregulating the CACNA1E gene.
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