公开(公告)号：WO2009134488A1

公开(公告)日：2009-11-05

申请号：PCT/US2009/032795

申请日：2009-02-02

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： HUNT, Bryan, V. ,  LINDSTROM, Kyle, J.

IPC: B32B17/10 ,  C08K5/134 ,  C08L33/04 ,  F21V9/00

CPC classification number: C08F220/30 ,  C08K5/105

Abstract: Optical films having a polymerized microstructured surface and polymerizable resin compositions are described comprising at least one ortho-benzylphenol mono(meth)acrylate monomer.

Abstract translation: 描述了具有聚合的微结构化表面和可聚合树脂组合物的光学膜包含至少一种邻苯甲基苯酚单（甲基）丙烯酸酯单体。

公开(公告)号：WO2011034722A2

公开(公告)日：2011-03-24

申请号：PCT/US2010/047264

申请日：2010-08-31

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： HAYS, David, S. ,  HANSEN, Richard, G. ,  JOHNSON, Stephen, A. ,  BENDING, Benjamin, J. ,  LINDSTROM, Kyle, J.

IPC: C08G77/455 ,  C08G77/26 ,  C08G73/10 ,  C08J5/18 ,  C09J183/10 ,  C08L83/10

CPC classification number: C08G77/26 ,  C08G69/00 ,  C08G69/42 ,  C08G77/455 ,  C08G77/50 ,  C08G77/80 ,  C09J183/04

Abstract: A copolymer comprises at least two repeating units of formula I: In this formula each R 1 is independently an alkyl, haloalkyl, aralkyl, alkenyl, aryl, or aryl substituted with an alkyl, alkoxy, or halo; each Y is independently an alkylene, aralkylene, or a combination thereof; each G is independently a bond or a divalent residue equal to a diamine of formula R 3 HN-G-NHR 3 minus the two -NHR 3 groups; each R 3 is independently hydrogen or alkyl or R 3 taken together with G and to the nitrogen to which they are both attached form a heterocyclic group; each n is independently an integer of 0 to 1500; each p is independently an integer of 1 to 10; and each q is independently an integer of 1 or greater, and wherein at least 50% of the q's are the integer 2.

Abstract translation: 共聚物包含至少两个式I的重复单元：在该式中，每个R 1独立地为被下列基团取代的烷基，卤代烷基，芳烷基，烯基，芳基或芳基： 烷基，烷氧基或卤素; 每个Y独立地为亚烷基，亚芳烷基或其组合; 每个G独立地是一个键或一个等于式R 3 HN-G-NHR 3的二胺减去两个-NHR 3的二价残基。 >组; 每个R 3独立地为氢或烷基或R 3与G一起并与它们所连接的氮一起形成杂环基; 每个n独立地为0至1500的整数; 每个p独立地为1至10的整数; 并且每个q独立地是1或更大的整数，并且其中至少50％的q是整数2。

公开(公告)号：WO2006038923A2

公开(公告)日：2006-04-13

申请号：PCT/US2005/021436

申请日：2005-06-17

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  NIWAS, Shri ,  MERRILL, Bryon, A. ,  HEPPNER, Philip, D. ,  KSHIRSAGAR, Tushar, A. ,  LUNDQUIST, Gregory, D., Jr. ,  AMOS, David, T. ,  LINDSTROM, Kyle, J.

Inventor： NIWAS, Shri ,  MERRILL, Bryon, A. ,  HEPPNER, Philip, D. ,  KSHIRSAGAR, Tushar, A. ,  LUNDQUIST, Gregory, D., Jr. ,  AMOS, David, T. ,  LINDSTROM, Kyle, J.

IPC: A61K31/4745 ,  C07D471/02

CPC classification number: C07D471/14

Abstract: Imidazonaphthyridine ring systems substituted with an aryl substituent, pharmaceutical compositions containing the compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

Abstract translation: 公开了用芳基取代基取代的咪唑并萘啶环体系，含有这些化合物的药物组合物，以及这些化合物作为免疫调节剂的用途，用于诱导动物中的细胞因子生物合成和治疗包括病毒和肿瘤疾病在内的疾病。

公开(公告)号：WO2009148818A1

公开(公告)日：2009-12-10

申请号：PCT/US2009/044461

申请日：2009-05-19

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  HUNT, Bryan, V. ,  LINDSTROM, Kyle, J. ,  DIZIO, James, P.

Inventor： HUNT, Bryan, V. ,  LINDSTROM, Kyle, J. ,  DIZIO, James, P.

IPC: C08F20/00 ,  C08L33/06

CPC classification number: C08F220/40 ,  B29K2033/12 ,  Y10S977/773

Abstract: Presently described are (e.g. microstructured) optical films and polymerizable resin compositions comprising at least one (meth)acrylate monomer comprising an unsubstituted or substituted phenyl ethylene group referred to as phenyl ethylene (meth)acrylate monomers.

Abstract translation: 目前描述的是（例如微结构的）光学薄膜和包含至少一种（甲基）丙烯酸酯单体的可聚合树脂组合物，所述单体包含被称为苯乙烯（甲基）丙烯酸酯单体的未取代或取代的苯基亚乙基。

公开(公告)号：WO2005032484A3

公开(公告)日：2005-04-14

申请号：PCT/US2004/032616

申请日：2004-10-01

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  LINDSTROM, Kyle, J. ,  MERRILL, Bryon, A. ,  HARALDSON, Chad, A. ,  RICE, Michael, J. ,  KSHIRSAGAR, Tushar, A. ,  HEPPNER, Philip, D. ,  WURST, Joshua, R. ,  NIWAS, Shri ,  JOHANNESSEN, Sarah, C.

Inventor： LINDSTROM, Kyle, J. ,  MERRILL, Bryon, A. ,  HARALDSON, Chad, A. ,  RICE, Michael, J. ,  KSHIRSAGAR, Tushar, A. ,  HEPPNER, Philip, D. ,  WURST, Joshua, R. ,  NIWAS, Shri ,  JOHANNESSEN, Sarah, C.

IPC: A61K31/4745

Abstract: Imidazoquinoline compounds with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.

公开(公告)号：WO2004110992A2

公开(公告)日：2004-12-23

申请号：PCT/US2004/017056

申请日：2004-05-28

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  LINDSTROM, Kyle, J. ,  DRESSEL, Luke, T. ,  BONK, Jason, D.

Inventor： LINDSTROM, Kyle, J. ,  DRESSEL, Luke, T. ,  BONK, Jason, D.

IPC: C07D

CPC classification number: C07D471/04 ,  C07D471/14

Abstract: A process and intermediates for preparing 1 H -imidazo[4,5- c ]pyridin-4-amines are disclosed. The process includes providing a 7 H -imidazo[4,5- c ]tetrazolo[1,5- a ]pyridine and converting a 7 H -imidazo[4,5- c ]tetrazolo[1,5- a ]pyridine to a 1 H -imidazo[4,5- c ]pyridin-4-amine.

Abstract translation: 公开了用于制备1H-咪唑并[4,5-c]吡啶-4-胺的方法和中间体。 该方法包括提供7H-咪唑并[4,5-c]四唑并[1,5-a]吡啶，并将7H-咪唑并[4,5-c]四唑并[1,5-a]吡啶转化为 -1H-咪唑并[4,5-c]吡啶-4-胺。

公开(公告)号：WO2009134594A1

公开(公告)日：2009-11-05

申请号：PCT/US2009/039734

申请日：2009-04-07

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： HUNT, Bryan, V. ,  LINDSTROM, Kyle, J.

IPC: C07C69/54 ,  C08F12/04

CPC classification number: C08F220/30 ,  C08F222/10 ,  C08F2220/306

Abstract: Microstructured optical films and polymerizable resin compositions comprising at one aromatic monomer or oligomer having at least two polymerizable (meth)acrylate groups and a fluorenol (meth)acrylate monomer.

Abstract translation: 微结构光学膜和可聚合树脂组合物，其包含一种具有至少两个可聚合（甲基）丙烯酸酯基团的芳族单体或低聚物和芴醇（甲基）丙烯酸酯单体。

公开(公告)号：WO2006091568A2

公开(公告)日：2006-08-31

申请号：PCT/US2006/006043

申请日：2006-02-22

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  KSHIRSAGAR, Tushar, A. ,  LANGER, Scott, E. ,  NIWAS, Shri ,  GRIESGRABER, George, W. ,  HEPPNER, Philip, D. ,  LINDSTROM, Kyle, J.

Inventor： KSHIRSAGAR, Tushar, A. ,  LANGER, Scott, E. ,  NIWAS, Shri ,  GRIESGRABER, George, W. ,  HEPPNER, Philip, D. ,  LINDSTROM, Kyle, J.

IPC: A61K31/4745

CPC classification number: C07D471/14

Abstract: Certain imidazonaphthyridines with a hydroxymethyl or hydroxyethyl substituent at the 2-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for preferentially inducing IFN-α biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

Abstract translation: 含有2-位羟基甲基或羟乙基取代基的咪唑并萘啶，含有化合物的药物组合物，中间体，制备方法以及这些化合物作为免疫调节剂的使用方法，用于优先诱导动物中的IFN-α生物合成和治疗疾病 包括病毒和肿瘤疾病。

公开(公告)号：WO2003050119A2

公开(公告)日：2003-06-19

申请号：PCT/US2002/018284

申请日：2002-06-07

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  DELLARIA, Joseph, F. ,  HARALDSON, Chad, A. ,  HEPPNER, Philip, D. ,  LINDSTROM, Kyle, J. ,  MERRILL, Bryon, A.

Inventor： DELLARIA, Joseph, F. ,  HARALDSON, Chad, A. ,  HEPPNER, Philip, D. ,  LINDSTROM, Kyle, J. ,  MERRILL, Bryon, A.

IPC: C07D471/04

CPC classification number: C07D471/04

Abstract: Imidazopyridine compounds that contain urea or thiourea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

Abstract translation: 在1位含有脲或硫脲官能团的咪唑并吡啶化合物可用作免疫应答调节剂。 本发明的化合物和组合物可以诱导各种细胞因子的生物合成，并且可用于治疗各种病症，包括病毒性疾病和肿瘤性疾病。

公开(公告)号：WO2008112452A2

公开(公告)日：2008-09-18

申请号：PCT/US2008/055654

申请日：2008-03-03

Applicant: 3M INNOVATIVE PROPERTIES COMPANY ,  HUNT, Bryan, V. ,  LINDSTROM, Kyle, J. ,  INVIE, Judith, M. ,  OLSON, David, B. ,  RENSTROM, Anthony, M.

Inventor： HUNT, Bryan, V. ,  LINDSTROM, Kyle, J. ,  INVIE, Judith, M. ,  OLSON, David, B. ,  RENSTROM, Anthony, M.

IPC: C08F32/06 ,  G02B5/00

CPC classification number: G02B1/10 ,  C07C43/23 ,  C07C69/734 ,  C07C69/78 ,  C08F32/06 ,  C08J5/18 ,  C08J2335/02 ,  G02B1/04 ,  G02B5/0231 ,  G02B5/045 ,  G02F1/133504 ,  G02F2001/133507 ,  Y10T428/10 ,  Y10T428/1036 ,  Y10T428/1041 ,  Y10T428/105

Abstract: Optical films are described having a polymerized microstructured surface that comprises the reaction product of a polymerizable resin composition comprising at least one polymerizable ethylenically unsaturated triphenyl monomer. Also described are certain triphenyl (meth)acrylate monomers and polymerizable resin compositions.

Abstract translation: 描述了具有聚合的微结构化表面的光学膜，其包含包含至少一个可聚合烯属不饱和三苯基单体的可聚合树脂组合物的反应产物。 还描述了某些三苯基（甲基）丙烯酸酯单体和可聚合树脂组合物。