公开(公告)号：WO2012170381A3

公开(公告)日：2013-04-04

申请号：PCT/US2012040840

申请日：2012-06-05

Applicant: ABBOTT LAB ,  FRITCHIE PATRICK P

Inventor： FRITCHIE PATRICK P

IPC: B04B5/04 ,  B04B9/14 ,  B04B11/04

CPC classification number: B04B5/0421 ,  B01D21/262 ,  B04B7/12 ,  B04B9/146 ,  B04B11/04 ,  B04B2011/046 ,  G01N2035/00504

Abstract: A centrifuge to which sample tubes can be introduced while the centrifuge is in motion. The centrifuge comprises a carousel (202) having an upper portion (204) and a lower portion (206). The upper portion of the carousel has a plurality of positions for sample tubes for a centrifugation operation, a plurality of drive mechanisms (230) attached to the upper portion of the carousel, a movable element (352) mounted upon each drive mechanism, the movable element capable of traversing the length of the drive mechanism when the drive mechanism is actuated, a sample tube-holding assembly (258) comprising a sample tube holder (260) and a bearing (262) attached to each movable element, and at least one balancing element (320, 322) capable of contributing to a force vector that cancels an imbalance vector generated by rotation of the centrifuge.

Abstract translation: 在离心机运动时可以将样品管引入的离心机。 离心机包括具有上部（204）和下部（206）的转盘（202）。 圆盘传送带的上部具有用于离心操作的样品管的多个位置，附接到转盘的上部的多个驱动机构（230），安装在每个驱动机构上的可移动元件（352），可移动的 元件，其能够在驱动机构被致动时穿过驱动机构的长度;样品管保持组件（258），包括样品管保持器（260）和附接到每个可移动元件的轴承（262），以及至少一个 平衡元件（320,322），其能够有助于抵消由离心机旋转产生的不平衡矢量的力矢量。

公开(公告)号：WO2010147896A3

公开(公告)日：2011-09-29

申请号：PCT/US2010038521

申请日：2010-06-14

Applicant: ABBOTT LAB ,  FRITCHIE PATRICK P ,  GARDNER GREGORY E ,  MAHONEY RICHARD W

Inventor： FRITCHIE PATRICK P ,  GARDNER GREGORY E ,  MAHONEY RICHARD W

IPC: G01N35/10

CPC classification number: G01N35/1002 ,  G01N1/28 ,  G01N35/1009 ,  G01N35/1016 ,  G01N35/1065 ,  G01N35/1074 ,  G01N2035/1025 ,  Y10T436/11 ,  Y10T436/25 ,  Y10T436/25625 ,  Y10T436/2575

Abstract: A system for managing bulk liquids for an automated clinical analyzer. The system comprises (a) at least one local reservoir for storing a bulk liquid for impending use, (b) at least one container for holding a bulk liquid before the liquid is transferred to a local reservoir, and (c) a controller for monitoring the level of a bulk liquid in a local reservoir. The local reservoir for storing a bulk liquid for impending use can be a trough. The use of troughs for storing a reagent, a diluent, or some other treating agent for impending use enables an aspirating/dispensing device having a plurality of pipettes to aspirate and dispense the reagent, diluent, or other treating agent at a high rate of throughput. The controller can monitor the level of a liquid in (a) a local reservoir for storing a bulk liquid for imminent use and the level of liquid in a (b) container for holding a bulk liquid before the liquid is transferred to a local reservoir. In the laboratory automation system described herein, the container for holding a bulk liquid before the liquid is transferred to a local reservoir can be a bottle. Other desirable features in the system include, but are not limited to, pump(s), valves, liquid level sensors.

Abstract translation: 用于管理自动化临床分析仪的散装液体的系统。 该系统包括（a）至少一个用于储存即将使用的散装液体的局部储存器，（b）至少一个用于在液体被转移到局部储存器之前保持散装液体的容器，以及（c）用于监测的控制器 局部水库中大量液体的水平。 用于储存即将使用的散装液体的局部储存罐可以是槽。 用于储存用于即将使用的试剂，稀释剂或一些其它处理剂的槽使得具有多个移液管的抽吸/分配装置可以以高生产率将吸入和分配试剂，稀释剂或其它处理剂 。 控制器可以监测（a）用于储存即将使用的散装液体的局部储存器中的液体的液面，以及（b）容器中用于容纳大量液体的液体的液面，然后液体被转移到局部储存器。 在本文所述的实验室自动化系统中，在将液体转移到局部储存器之前用于保持散装液体的容器可以是瓶子。 该系统中的其它期望特征包括但不限于泵，阀，液位传感器。

公开(公告)号：WO2009061641A3

公开(公告)日：2009-08-27

申请号：PCT/US2008081494

申请日：2008-10-29

Applicant: ABBOTT LAB ,  FRITCHIE PATRICK P ,  GARDNER GREGORY E ,  MAHONEY RICHARD W

Inventor： FRITCHIE PATRICK P ,  GARDNER GREGORY E ,  MAHONEY RICHARD W

IPC: B01L3/00 ,  C12Q1/68 ,  G01N35/00

CPC classification number: G01N35/028 ,  B01L3/5085 ,  B01L2300/0829 ,  G01N35/0098 ,  G01N35/0099 ,  G01N35/1002 ,  G01N35/1065 ,  G01N2035/00564 ,  G01N2035/0406 ,  G01N2035/1051 ,  Y02P20/582 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/2575

Abstract: A laboratory automation system that is capable of carrying out clinical chemistry assays, immunoassays, amplification of nucleic acid assays, and any combination of the foregoing, said laboratory automation system employing at least one of micro-well plates and deep multi-well plates as reaction vessels. The use of micro-well plates as reaction vessels enables the laboratory automation system to assume a variety of arrangements, i.e., the laboratory automation system can comprise a variety of functional modules that can be arranged in various ways. In order to effectively carry out immunoassays by means of micro-well plates, a technique known as inverse magnetic particle processing can be used to transfer the product(s) of immunoassays from one micro-well of a micro-well plate to another.

Abstract translation: 实验室自动化系统能够进行临床化学测定，免疫测定，核酸测定的扩增以及前述的任何组合，所述实验室自动化系统采用微孔板和深度多孔板中的至少一种作为反应 船只。 使用微孔板作为反应容器使得实验室自动化系统能够采取各种布置，即，实验室自动化系统可以包括可以以各种方式布置的各种功能模块。 为了有效地通过微孔板进行免疫测定，可以使用称为反向磁性颗粒处理的技术将免疫测定的产物从微孔板的一个微孔转移到另一微孔板。

公开(公告)号：WO2008014117A2

公开(公告)日：2008-01-31

申请号：PCT/US2007073201

申请日：2007-07-11

Applicant: ABBOTT LAB ,  FRITCHIE PATRICK P ,  GARDNER GREGORY E ,  MAHONEY RICHARD W ,  SCHWARTZ OSCAR F

Inventor： FRITCHIE PATRICK P ,  GARDNER GREGORY E ,  MAHONEY RICHARD W ,  SCHWARTZ OSCAR F

IPC: G01N35/00

CPC classification number: G01N35/00732 ,  B01L3/545 ,  B01L2300/022 ,  B01L2300/024 ,  G01N2035/00782 ,  G01N2035/00851

Abstract: A system for automation of laboratory analyzers that utilizes radio frequency identification (RFID) tags and radio frequency identification (RFID) readers to identify containers and vessels, and the contents thereof, that are employed in the system. Radio frequency identification tags, conforming to the guidelines of ISO 14443 or ISO 15693 or ISO 18000, are positioned on the items of interest, such as, for example, reagent containers, sample containers, and microplates. These tags can be read by and written to by either a moving antenna of a RFID reader or a stationary antenna of a RFID reader. Reading of RFID tags and writing to RFID tags are controlled by software.

Abstract translation: 实验室分析仪自动化系统，利用射频识别（RFID）标签和射频识别（RFID）读取器识别系统中使用的容器和容器及其内容。 射频识别标签符合ISO 14443或ISO 15693或ISO 18000标准，位于感兴趣的项目上，例如试剂容器，样品容器和微孔板。 这些标签可以通过RFID阅读器的移动天线或RFID阅读器的固定天线读取和写入。 读取RFID标签并写入RFID标签由软件控制。