公开(公告)号：WO2019068935A1

公开(公告)日：2019-04-11

申请号：PCT/EP2018/077355

申请日：2018-10-08

Applicant: ALFA INSTRUMENTS S.R.L.

Inventor： DAVID, Fabio

IPC: C09B11/20 ,  A61K49/00 ,  C07C309/49 ,  G01N33/68 ,  C07C309/46

CPC classification number: C09B11/20 ,  A61K49/0023 ,  A61K49/006 ,  C07C309/46 ,  C07C309/49 ,  G01N33/6839

Abstract: The present invention relates to dye molecules and to staining compositions comprising said dye molecules that are particularly suitable for selectively staining biological substrates, such as structures in the posterior eye segment and proteins. Said dye molecules may be used in ophthalmic surgery to help the surgeon to visualize structures in the posterior eye structures as well as in protein assays to determine one or more analytical parameter of a protein. The dye molecules have the following structure (I) wherein X represents an organic or inorganic cation; and R 1 represents a substituted or unsubstituted benzyl group. The present invention relates also to a new method for synthetizing dye molecules.

公开(公告)号：WO2019068355A1

公开(公告)日：2019-04-11

申请号：PCT/EP2017/075562

申请日：2017-10-06

Applicant: ALFA INSTRUMENTS S.R.L.

Inventor： DAVID, Fabio

IPC: C09B11/20 ,  A61K49/00 ,  C07C309/49 ,  G01N33/68

CPC classification number: C09B11/20 ,  A61K49/0023 ,  A61K49/006 ,  C07C309/46 ,  C07C309/49 ,  G01N33/6839

Abstract: The present invention relates to dye molecules and to staining compositions comprising said dye molecules that are particularly suitable for selectively staining biological substrates, such as structures in the posterior eye segment and proteins. Said dye molecules may be used in ophthalmic surgery to help the surgeon to visualize structures in the posterior eye structures as well as in protein assays to determine one or more analytical parameter of a protein. The present invention relates also to a new method for synthetizing dye molecules.