DYE INTERMEDIATE AND METHOD
    5.
    发明申请
    DYE INTERMEDIATE AND METHOD 审中-公开
    DYE中间和方法

    公开(公告)号:WO99007793A1

    公开(公告)日:1999-02-18

    申请号:PCT/GB1998/002334

    申请日:1998-08-04

    摘要: Various classes of dyes are provided having acid, ester or amide groups for covalent linking to biomolecules. The dyes may be prepared by use of a compound of formula (I) where R comprises a linker and a carboxy including acid, salt, ester including N-hydroxysuccinimide, activated ester or amide group; R , R , R and R are H, C1-C10 alkyl or aralkyl or a group to modify solubility or electronic or spectral properties or a functional linking group: or R -R and/or R -R and/or R -R are linked to form an extended ring system; and R is H or CHO or NO.

    摘要翻译: 提供了具有酸,酯或酰胺基团以共价连接生物分子的各种类型的染料。 染料可以通过使用式(I)化合物制备,其中R 1包含连接基和羧基,包括酸,盐,酯,包括N-羟基琥珀酰亚胺,活化的酯或酰胺基; R 2,R 3,R 4和R 5是H,C 1 -C 10烷基或芳烷基或修饰溶​​解度或电子或光谱性质或官能连接基团的基团:或R 4, -R 5和/或R 2 -R 4和/或R 2 -R 3连接形成延伸的环系; R 6为H或CHO或NO。