-
公开(公告)号:WO03005889A2
公开(公告)日:2003-01-23
申请号:PCT/US0222432
申请日:2002-07-09
Applicant: AMS RES CORP
Inventor: NEISZ JOHANN J , ESCANDON M ALEJANDRO SOUSA
CPC classification number: A61B17/32037 , A61B17/3403 , A61B17/3478 , A61B2017/00274 , A61B2017/003 , A61B2017/22082 , A61B2017/2946 , A61B2018/00547 , A61B2090/035 , A61B2090/0801 , A61M5/486 , A61M5/488 , Y10S514/874
Abstract: The invention provides a treatment regimen for treating diseased prostate tissue, including the steps of chemically ablating prostate tissue and coadministering an antiandrogen. In some embodiments, prostate tissue is ablated by injection of ethanol into prostate tissue. Steroidal and non-steroidal antiandrogens are suitable. One suitable antiandrogen is bicalutamide. The treatment regimen is suitable for treatment of prostate tissue diseases including benign prostatic hyperplasia and prostatic carcinoma. The invention further provides a treatment regimen for treating benign prostatic hyperplasia, including the steps of damaging prostate tissue and coadministering an antiandrogen. Also provided by the invention is a kit for treating a human male, including means for necrosing prostate tissue, an antiandrogen drug, and means for administering the antiandrogen drug. A kit including a first surgical device for delivering a chemoablation fluid to prostate tissue transurethrally, an antiandrogen drug, and a second surgical device for administering the antiandrogen drug, is provided.
Abstract translation: 本发明提供了治疗患病前列腺组织的治疗方案,包括化学消融前列腺组织并共同施用抗雄激素的步骤。 在一些实施方案中,通过将乙醇注射到前列腺组织中来消融前列腺组织。 类固醇和非甾体抗雄激素是合适的。 一种合适的抗雄激素是比卡鲁胺。 治疗方案适用于治疗前列腺组织疾病,包括良性前列腺增生和前列腺癌。 本发明还提供了治疗良性前列腺增生的治疗方案,包括损害前列腺组织和共施用抗雄激素的步骤。 本发明还提供了一种用于治疗人类雄性的试剂盒,包括用于坏死前列腺组织的方法,抗雄激素药物和用于施用抗雄激素药物的方法。 提供了一种试剂盒,其包括用于将化学消化液输送到经尿道前列腺组织的第一手术装置,抗雄激素药物和用于施用抗雄激素药物的第二手术装置。
-
公开(公告)号:WO03030756A3
公开(公告)日:2003-08-21
申请号:PCT/US0232573
申请日:2002-10-11
Applicant: AMS RES CORP
Inventor: HAUSCHILD SIDNEY F , BOLEA STEPHEN L , NEISZ JOHANN J
CPC classification number: A61M5/3287 , A61B17/32037 , A61B17/3403 , A61B17/3478 , A61B2017/00274 , A61B2017/003 , A61B2017/22082 , A61B2017/2946 , A61B2018/00547 , A61B2090/035 , A61B2090/0801 , A61M5/3007 , A61M5/486 , A61M5/488
Abstract: Method and surgical instrument for treating prostate tissue including a surgical instrument having a main body, a needle deployment port, a needle, first and second handles (34, 30) and a lockout release mechanism (42) to limit needle extension, Additionally, a kit includes the surgical instrument, together with a cystoscope, and optionally a syringe and reservoir of ethanol. The method includes needle- less injection and visualizing the ethanol injection by delivering both an echogenic agent and ethanol either by needle or needle-less injection or by providing an ultrasonically visible marker near the tip of the ethanol delivery cannula. The method also includes extending the needle transversely of the instrument housing using a link assembly.
Abstract translation: 用于治疗前列腺组织的方法和手术器械,包括具有主体,针展开口,针头,第一和第二手柄(34,30)和限制针伸出的锁定释放机构(42)的外科器械。另外, 套件包括手术器械,连同膀胱镜,以及任选的注射器和乙醇储存器。 该方法包括无针注射和可视化乙醇注射,通过针或无针注射递送回声剂和乙醇,或通过在乙醇递送插管的尖端附近提供超声波可见标记。 该方法还包括使用连杆组件将针横向延伸到仪器壳体。
-
公开(公告)号:WO02078571A3
公开(公告)日:2003-04-10
申请号:PCT/US0209455
申请日:2002-03-28
Applicant: AMS RES CORP
Inventor: NEISZ JOHANN J , ANDERSON KIMBERLY A , WATSCHKE BRIAN P , LUND ROBERT E , GOHMAN JAMES A
CPC classification number: A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/06109 , A61B2017/00495 , A61B2017/00805 , A61B2017/00946 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0417 , A61B2017/0435 , A61B2017/0437 , A61B2017/0438 , A61B2017/044 , A61B2017/0443 , A61B2017/0458 , A61B2017/0464 , A61F2/0045
Abstract: The present invention discloses an implant 10 for placement in the retropubic space of a patient. Novel methods and assemblies for use in conjunction with the implant are also described. The assemblies comprise at least one deployable member 56 for associating the implant with endopelvic fascia 15 of a retropublic space, and an inserter 80 that is sized and and shaped to associate the deployable member with endopelvic fascia.
Abstract translation: 本发明公开了一种用于放置在患者的耻垢后空间中的植入物10。 还描述了与植入物一起使用的新颖方法和组件。 组件包括至少一个可展开构件56,用于将植入物与再共享空间的内腹筋膜15相关联,以及插入器80,其尺寸和形状使得可展开构件与内耳筋膜相关联。
-
公开(公告)号:WO03075792A9
公开(公告)日:2004-03-04
申请号:PCT/US0306465
申请日:2003-03-04
Applicant: AMS RES CORP
Inventor: ANDERSON KIMBERLY A , WATSCHKE BRIAN P , MELLIER GEORGES , NEISZ JOHANN J
IPC: A61B17/00 , A61B17/04 , A61B17/06 , A61B17/30 , A61B17/32 , A61B19/00 , A61B19/02 , A61F2/00 , A61F2/48
CPC classification number: A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/06066 , A61B17/06109 , A61B17/30 , A61B17/3211 , A61B50/30 , A61B90/02 , A61B2017/00805 , A61B2017/00946 , A61B2017/0417 , A61B2017/06009 , A61B2017/06076 , A61B2017/320056 , A61F2/0045 , A61F2002/30708 , A61F2250/0084
Abstract: Surgical articles, implants and components suitable for a transobturator surgical procedure are described.
Abstract translation: 描述了适用于跨导管外科手术的外科用品,植入物和组件。
-
-
-