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    IMPLANTABLE MECHANICAL SUPPORT
    1.
    发明申请
    IMPLANTABLE MECHANICAL SUPPORT 审中-公开
    可植入机械支持

    公开(公告)号：WO2011143572A1

    公开(公告)日：2011-11-17

    申请号：PCT/US2011036455

    申请日：2011-05-13

    Applicant: AMS RES CORP ,  WATSCHKE BRIAN P ,  WANG GUANGJIAN

    Inventor： WATSCHKE BRIAN P ,  WANG GUANGJIAN

    IPC: A61N1/36 ,  A61F2/00 ,  A61N1/05

    CPC classification number: A61F2/0045 ,  A61B6/12 ,  A61F2210/0004 ,  A61F2250/0098 ,  A61N1/0514 ,  A61N1/0521 ,  A61N1/36007

    Abstract: Embodiments of the invention are generally directed to a mechanical support (102) of a pelvic treatment apparatus (100) that is configured for implantation in the pelvic region of a patient for the purpose of treating a pelvic condition of the patient, such as urinary incontinence, fecal incontinence, sexual dysfunction, or other pelvic related condition. In some embodiments, the implantable mechanical support comprises a section of mesh (104) having a longitudinal axis (106) and at least one radiopaque mark (114) covering a subsection of the section of mesh. Additional embodiments are directed to methods of attaching an electrode lead (122) or an electrical lead (180) to the mechanical support subsequent to the implantation of the mechanical support using the radiopaque mark.

    Abstract translation: 本发明的实施例通常涉及骨盆治疗装置（100）的机械支撑件（102），其被配置为植入患者的骨盆区域中，以便治疗患者的盆腔状况，例如尿失禁 ，大便失禁，性功能障碍或其他盆腔相关病症。 在一些实施例中，可植入机械支撑件包括具有纵向轴线（106）和覆盖网状部分的子部分的至少一个不透射线标记（114）的网状部分（104）。 另外的实施例涉及在使用不透射线标记注入机械支撑件之后将电极引线（122）或电引线（180）附接到机械支撑件的方法。

    CELL DELIVERY DEVICE AND SYSTEM WITH ANTI-CLUMPING FEATURE AND METHODS FOR PELVIC TISSUE TREATMENT
    3.
    发明申请
    CELL DELIVERY DEVICE AND SYSTEM WITH ANTI-CLUMPING FEATURE AND METHODS FOR PELVIC TISSUE TREATMENT 审中-公开
    细胞输送装置和具有抗绷带特征的系统和用于组织治疗的方法

    公开(公告)号：WO2014078506A3

    公开(公告)日：2014-07-10

    申请号：PCT/US2013070049

    申请日：2013-11-14

    Applicant: AMS RES CORP

    Inventor： SCHROEDER TANIA M ,  WATSCHKE BRIAN P ,  MARKS ISAAC ,  YONCE DAVID J

    IPC: A61M5/32

    CPC classification number: A61M5/3129 ,  A61F2/022 ,  A61K35/35 ,  A61M5/3145 ,  A61M31/00 ,  A61M37/00 ,  A61M2025/0073 ,  A61M2206/14

    Abstract: The invention is directed to cell delivery devices for providing a cell composition to a tissue or organ in the pelvic area for the treatment of a pelvic disorder. In some arrangements, the device has a cell delivery conduit that includes a turbulence-inducing feature that introduces sheer forces in the flow of liquid composition through the conduit, resulting in reduced cell clumping and improved single state cell delivery to the target tissue. In other arrangements, the device has a microfluidics channel which provides a similar effect for cell delivery. The resulting cell delivery can provide improved seeding of cells at the target tissue or organ and an improved therapeutic effect.

    Abstract translation: 本发明涉及用于向骨盆区域中的组织或器官提供细胞组合物以用于治疗骨盆疾病的细胞递送装置。 在一些配置中，所述装置具有细胞输送导管，所述细胞输送导管包括湍流引发特征，所述湍流诱导特征在液体组合物流中通过导管引入剪切力，导致细胞团块减少并且改善单状态细胞递送至目标组织。 在其他布置中，该装置具有微流体通道，其为细胞递送提供类似的效果。 所得到的细胞递送可以改善目标组织或器官细胞的接种和改善的治疗效果。

    IMPLANTABLE ELECTRODE ASSEMBLY
    4.
    发明申请
    IMPLANTABLE ELECTRODE ASSEMBLY 审中-公开
    可植入电极组件

    公开(公告)号：WO2013036399A3

    公开(公告)日：2013-06-27

    申请号：PCT/US2012052602

    申请日：2012-08-28

    Applicant: AMS RES CORP ,  GINDELE PAUL J ,  WATSCHKE BRIAN P

    Inventor： GINDELE PAUL J ,  WATSCHKE BRIAN P

    IPC: A61N1/05 ,  A61N1/36

    CPC classification number: A61N1/05 ,  A61N1/0514 ,  A61N1/36007 ,  A61N1/36071 ,  A61N1/36107

    Abstract: An implantable electrode assembly (104) configured to deliver electrical stimulation signals to tissue of a patient includes an implantable mesh (108) comprising a plurality of electrically conductive wires (114). A plurality of electrodes (106) are fastened to the electrically conductive wires. The electrodes include a stimulation surface (134) and an electrically conductive path between the stimulation surface and the wire, to which the electrode is attached. In one embodiment, the plurality of electrodes each comprise first and second members (130, 132) that are fastened together around one of the electrically conductive wires.

    Abstract translation: 构造成将电刺激信号传递给患者组织的可植入电极组件（104）包括包括多个导电线（114）的可植入网（108）。 多个电极（106）被紧固到导电线上。 电极包括刺激表面（134）和刺激表面和电线之间的导电路径，电极附接到该电极。 在一个实施例中，多个电极各自包括围绕导电线之一紧固在一起的第一和第二构件（130,132）。

    METHOD AND APPARATUS FOR TREATING PELVIC ORGAN PROLAPSE
    5.
    发明申请
    METHOD AND APPARATUS FOR TREATING PELVIC ORGAN PROLAPSE 审中-公开
    用于治疗皮肤器官的方法和装置

    公开(公告)号：WO2005110273B1

    公开(公告)日：2006-01-26

    申请号：PCT/US2005012805

    申请日：2005-04-14

    Applicant: AMS RES CORP ,  COX JAMES E ,  ANDERSON KIMBERLY A ,  LUND ROBERT E ,  WATSCHKE BRIAN P

    Inventor： COX JAMES E ,  ANDERSON KIMBERLY A ,  LUND ROBERT E ,  WATSCHKE BRIAN P

    IPC: A61B17/00 ,  A61B17/04 ,  A61B17/06 ,  A61F2/00

    CPC classification number: A61B17/06109 ,  A61B17/06004 ,  A61B17/06066 ,  A61B2017/0042 ,  A61B2017/00805 ,  A61F2/0045

    Abstract: A method of treating pelvic organ prolapse is provided. The method generally includes the steps of establishing a first pathway between the external perirectal region of the patient to the region of the ischial spine in tissue on one side of the prolapsed organ, followed by establishing a second pathway in tissue on the contralateral side of the prolapsed organ. A support member, which includes a central support portion (2) and two end portions (32), is positioned in a position to reposition said prolapsed organ in said organ's anatomically correct location. The end portions of the support member are introduced through the respective tissue pathways, followed by adjustment of the end portions so that the support member is located in a therapeutic relationship to the prolapsed organ that is to be supported. An apparatus and kit for said treatment is further provided.

    Abstract translation: 提供了治疗盆腔器官脱垂的方法。 该方法通常包括以下步骤：在脱垂的器官的一侧上的组织中，在患者的外部经周期区域之间建立坐骨坐标的区域中的第一路径，然后在组织中建立第二路径 脱垂器官 包括中心支撑部分（2）和两个端部部分（32）的支撑构件被定位成在所述器官的解剖学正确位置中重新定位所述脱垂的器官的位置。 支撑构件的端部通过相应的组织通道引入，随后调节端部，使得支撑构件位于与被支撑的脱垂的器官的治疗关系中。 还提供了用于所述处理的装置和试剂盒。

    ELECTRODE IMPLANTATION TOOL
    7.
    发明申请
    ELECTRODE IMPLANTATION TOOL 审中-公开
    电极植入工具

    公开(公告)号：WO2010107900A3

    公开(公告)日：2010-11-11

    申请号：PCT/US2010027643

    申请日：2010-03-17

    Applicant: AMS RES CORP ,  WATSCHKE BRIAN P ,  BUYSMAN JOHN J ,  GINDELE PAUL J ,  MOOSAI SHIVA P

    Inventor： WATSCHKE BRIAN P ,  BUYSMAN JOHN J ,  GINDELE PAUL J ,  MOOSAI SHIVA P

    IPC: A61N1/05 ,  A61B17/34 ,  A61M25/01 ,  A61N1/36

    CPC classification number: A61N1/05 ,  A61B17/3403 ,  A61B17/3468 ,  A61B2017/00805 ,  A61B2017/3407 ,  A61M25/0017 ,  A61M25/01 ,  A61M25/0113 ,  A61M25/10 ,  A61N1/36007

    Abstract: Embodiments of the invention are directed to an electrode implantation tool that is designed to assist in the accurate implantation of one or more electrodes in tissue of a patient. One embodiment of the electrode implantation tool (130) comprises a catheter guide and introducer support (140), and catheter guide (142) and an introducer (144). The catheter guide and introducer support comprises a first alignment member (146), a second alignment member (148), and a body member (150) that is attached to the first and second alignment members. The body member fixes the relative orientations of the first and second alignment members. The catheter guide is supported by the first alignment member and comprises an elongate body (152) having a distal end (154) and a channel (156) that is aligned with a longitudinal axis (158). The introducer comprises a sheath (166) that is supported by the second alignment member. The sheath defines a longitudinal axis (168). The first and second alignment members orient the longitudinal axis of the sheath at a predetermined angle (184) to the longitudinal axis of the catheter guide.

    Abstract translation: 本发明的实施例涉及一种电极植入工具，其被设计成有助于将一个或多个电极精确地植入患者的组织中。 电极植入工具（130）的一个实施例包括导管引导件和引导器支撑件（140）以及导管引导件（142）和导引器（144）。 导管引导件和引导器支撑件包括第一对准构件（146），第二对准构件（148）和附接到第一和第二对准构件的本体构件（150）。 主体构件固定第一和第二对准构件的相对取向。 导管引导件由第一对准构件支撑并且包括具有远端（154）的细长主体（152）和与纵向轴线（158）对准的通道（156）。 引导器包括由第二对准构件支撑的护套（166）。 护套限定纵向轴线（168）。 第一和第二对准构件将护套的纵向轴线以与导管引导件的纵向轴线成预定角度（184）定向。

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