公开(公告)号：WO2019122144A1

公开(公告)日：2019-06-27

申请号：PCT/EP2018/086226

申请日：2018-12-20

Applicant: BASF SE

Inventor： HOFF, Birgit ,  BOEHMER, Nico ,  HAEFNER, Stefan ,  SCHROEDER, Hartwig ,  ZELDER, Oskar ,  WITTMANN, Christoph ,  SCHROER, Anna Christine

IPC: C12N9/02 ,  C12P7/46

Abstract: The present invention relates to a process of producing an organic compound, the process comprising I) cultivating a genetically modified microorganism in a culture medium comprising at least one assimilable carbon source to allow the genetically modified microorganism to produce the organic compound, II) recovering the organic compound from the fermentation broth obtained in process step I), wherein the genetically modified microorganism comprises A) at least one genetic modification that leads to an increased activity of the enzyme encoded by the udhA-gene, compared to the original microorganism that has not been genetically modified, and wherein the original microorganism belongs to the family Pasteurellaceae. The present invention also relates to a genetically modified microorganism and to the use thereof for the fermentative production of an organic compound from at least one assimilable carbon source.