中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

3 records (took 0.011 seconds)

    IMMUNOCONJUGATES MADE OF EGG-YOLK ANTIBODIES (IGY), PRODUCTION AND USE THEREOF IN DIAGNOSES AND THERAPY
    1.
    发明申请
    IMMUNOCONJUGATES MADE OF EGG-YOLK ANTIBODIES (IGY), PRODUCTION AND USE THEREOF IN DIAGNOSES AND THERAPY 审中-公开
    蛋黄抗体（IgY抗体），它们的制造和使用诊断和治疗免疫偶联

    公开(公告)号：WO02092136A3

    公开(公告)日：2003-09-18

    申请号：PCT/DE0201606

    申请日：2002-05-03

    Applicant: BERGTER WOLFGANG ,  KOBILKE HARTMUT ,  SROKA JOACHIM

    Inventor： BERGTER WOLFGANG ,  KOBILKE HARTMUT

    IPC: G01N33/531 ,  A61K39/395 ,  A61K41/00 ,  A61K47/48 ,  A61K51/00 ,  A61K51/10 ,  A61P7/02 ,  A61P29/00 ,  A61P31/04 ,  A61P35/00 ,  A61P37/02 ,  A61K49/00

    CPC classification number: B82Y5/00 ,  A61K41/0057 ,  A61K41/0071 ,  A61K47/6898 ,  A61K51/1006 ,  A61K51/1027 ,  A61K51/1036 ,  A61K51/1093

    Abstract: The invention relates to immunoconjugates made of egg-yolk antibodies (IgY), the production and use thereof in diagnoses and therapy. The aim of the invention is to provide alternative products to traditional immunoconjugates for use in diagnoses and therapy. The inventive immunoconjugates are superior to monoclonal antibodies and immune serums from mammals in addition to IgY preparations from conventional hens in terms of purity and antigen targeting. The invention seeks to avoid the formation of human anti-IgY antibodies as far as possible, and to produce immunoconjugates in large quantities at a low price in a manner which is compatible with animal welfare. This is achieved by polyclonal IgY conjugates from intact egg-yolk antibodies (IgY), IgY fragments, Fab constructions or humanized egg-yolk antibodies form SPF hens, preferably from transgenic SPF hens. The antibodies or antibody fragments are conjugated as immunologically effective components with at least one other component such as a signaling substance, an active substance or an amplifier module.

    Abstract translation: 本发明涉及一种从蛋黄抗体（IgY），任何在诊断和治疗中的封装和应用免疫偶联物。 本发明的目的是提出替代产品，以用于诊断和治疗用途的传统免疫缀合物。 新颖的免疫缀合物都优于单克隆从哺乳动物和从常规鸡的IgY制剂的抗体和免疫血清中的纯度和抗原靶向条款。 也应避免人抗IgY抗体抗体的形成，和免疫缀合物应来制备人性化和成本效益的大批量。 该目的通过多克隆IgY抗体缀合物从完整蛋黄抗体（IgY），任何的IgY片段实现的Fab构建体或从SPF鸡胚人源化蛋黄抗体，优选从转基因SPF鸡胚。 所述抗体或抗体片段将被缀合与至少一种另外的组分免疫学活性成分，其可以是药物或增强分子是信号物质。

    COMPOSITION FOR PHARMACEUTICAL AND COSMETIC PRODUCTS
    2.
    发明申请
    COMPOSITION FOR PHARMACEUTICAL AND COSMETIC PRODUCTS 审中-公开
    药妆和化妆品的组合物

    公开(公告)号：WO0202642A3

    公开(公告)日：2002-04-18

    申请号：PCT/DE0102589

    申请日：2001-07-05

    Applicant: BERGTER WOLFGANG ,  KOBILKE HARTMUT

    Inventor： KOBILKE HARTMUT

    IPC: A61K39/40 ,  C07K16/12 ,  C07K16/02 ,  A61K7/48 ,  A61K31/355 ,  A61K31/375 ,  A61K31/65 ,  A61K35/78 ,  A61K39/395 ,  A61K47/44

    CPC classification number: C07K16/12 ,  A61K35/748 ,  A61K39/40 ,  A61K2039/505 ,  C07K2317/11 ,  A61K2300/00

    Abstract: The invention relates to a composition for pharmaceutical and cosmetic products in addition to the use thereof for treating injuries, particularly in cases of persistent and acute chronical inflammation, by administration of said inventive composition comprising immunoglobulin. The inventive composition is characterised in that the fundamental active component is Ig Y in egg yolks (mono- or polyvalent) from SPF chickens, micro algae extracts, preferably from the spirulina and chlorella variety, with or without oxytetracycline. Said composition can be used by humans and animals in liquid, paste or solid form, particularly as a cream, oil, liquid plaster, aerosol or in tablets or powder.

    Abstract translation: 本发明涉及一种用于药物和化妆品的组合物，以及由含免疫球蛋白的本发明组合物的施用它们对伤口的治疗应用，特别是急性和慢性持续性炎症。 本发明组合物的特征在于，从SPF鸡，微藻提取物，优选选自Spirulinaarten和小球藻物种和Oxytetracyclinum或可替代地不Oxytetracyclinum基本活性成分的Ig的Y蛋黄（单价或多价）。 该组合物发现在人类和动物中的液体，糊状或固体形式应用，尤其是作为软膏，油，液体膏药，喷雾，或在片剂或粉末形式。

Patent Agency Ranking