公开(公告)号：WO2013185084A1

公开(公告)日：2013-12-12

申请号：PCT/US2013/044800

申请日：2013-06-07

Applicant: BIOGEN IDEC MA INC. ,  SUNESIS PHARMACEUTICALS, INC.

Inventor： HOPKINS, Brian T. ,  CONLON, Patrick ,  CHAN, Timothy R. ,  JENKINS, Tracy J. ,  CAI, Xiongwei ,  HUMORA, Michael ,  SHI, Xianglin ,  MILLER, Ross A. ,  THOMPSON, Andrew

IPC: A01N43/40 ,  A61K31/435 ,  A61K31/445

CPC classification number: C07D401/14

Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

Abstract translation: 本发明提供了可用作Bruton酪氨酸激酶抑制剂的化合物及其组合物，其表现出所需特性。

公开(公告)号：WO2015089327A1

公开(公告)日：2015-06-18

申请号：PCT/US2014/069839

申请日：2014-12-11

Applicant: BIOGEN IDEC MA INC. ,  SUNESIS PHARMACEUTICALS, INC.

Inventor： HOPKINS, Brian T. ,  MA, Bin ,  CHAN, Timothy Raymond ,  KUMARAVEL, Gnanasambandam ,  MIAO, Hua ,  BERTOLOTTI-CIARLET, Andrea ,  OTIPOBY, Kevin

IPC: C07D471/04 ,  C07D473/00 ,  C07D487/04 ,  C07D513/04 ,  A61K31/519 ,  A61K31/52 ,  A61P25/02 ,  A61P35/00 ,  A61P37/00

CPC classification number: C07D487/04 ,  C07D471/04 ,  C07D473/00 ,  C07D513/04 ,  C07D519/00 ,  G01N33/573 ,  G01N2333/9121

Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

Abstract translation: 本发明提供了可用作Bruton酪氨酸激酶抑制剂的化合物及其组合物，并且其表现出所需特性。