公开(公告)号：WO2019185646A3

公开(公告)日：2019-10-03

申请号：PCT/EP2019/057617

申请日：2019-03-26

Applicant: BIOME BIOPLASTICS LIMITED

Inventor： MINES, Paul ,  LAW, Paul ,  CARNELL, Andrew ,  MCKENNA, Shane ,  BLACKER, John ,  KAPUR, Nikil

IPC: C12P17/04 ,  C12M1/40 ,  C12M1/24 ,  C07D307/50 ,  C07D307/68 ,  B01J14/00 ,  C08G63/181 ,  B01F5/06 ,  B01F5/04 ,  B01F13/00 ,  B01F3/08 ,  C12P7/44

Abstract: A process for oxidising a substrate selected from hydroxymethylfurfural (HMF), diformylfuran (DFF), hydroxymethylfurancarboxylic acid (HMFCA) and formylfurancarboxylic acid (FFCA). Said process comprises mixing said substrate with catalase, one or more further enzymes and hydrogen peroxide to form a reaction mixture. Said one or more further enzymes have the ability to catalyse oxidation of said substrate. Said hydrogen peroxide is provided at a total molar ratio of at least about 0.1:1 hydrogen peroxide to substrate.

公开(公告)号：WO2019185646A2

公开(公告)日：2019-10-03

申请号：PCT/EP2019/057617

申请日：2019-03-26

Applicant: BIOME BIOPLASTICS LIMITED

Inventor： MINES, Paul ,  LAW, Paul ,  CARNELL, Andrew ,  MCKENNA, Shane ,  BLACKER, John ,  KAPUR, Nikil

IPC: C12P17/04 ,  C12M1/40 ,  C12M1/24 ,  C07D307/50 ,  C07D307/68 ,  B01J14/00 ,  C08G63/181

Abstract: A process for oxidising a substrate selected from hydroxymethylfurfural (HMF), diformylfuran (DFF), hydroxymethylfurancarboxylic acid (HMFCA) and formylfurancarboxylic acid (FFCA). Said process comprises mixing said substrate with catalase, one or more further enzymes and hydrogen peroxide to form a reaction mixture. Said one or more further enzymes have the ability to catalyse oxidation of said substrate. Said hydrogen peroxide is provided at a total molar ratio of at least about 0.1:1 hydrogen peroxide to substrate.

公开(公告)号：WO2016202858A1

公开(公告)日：2016-12-22

申请号：PCT/EP2016/063757

申请日：2016-06-15

Applicant: BIOME BIOPLASTICS LIMITED

Inventor： LAW, Paul ,  MINES, Paul ,  CARNELL, Andrew ,  MCKENNA, Shane

IPC: C07K14/435 ,  C08G63/02 ,  C12P7/62 ,  C12P17/04

CPC classification number: C12P17/04 ,  C08G63/181 ,  C08G63/199 ,  C08L67/02 ,  C12N9/0006 ,  C12P7/625 ,  C12Y101/03009 ,  C12Y102/01003 ,  C12Y106/03001 ,  C12Y111/01006 ,  C12Y111/01007 ,  C12Y117/03002

Abstract: The present invention relates to processes for the formation of furandicarboxylic acid (FDCA), in particular 2,5-furandicarboxylic acid (2,5-FDCA), and mono- and diester derivatives thereof, via a multistep biocatalytic oxidation reaction of 5-hydroxymethylfurfural (HMF) using, for example, an enzyme selected from the group consisting of xanthine oxidoreductase (XOR), galactose oxidase variant M 3-5 , aldehyde dehydrogenase, and/or ketoreductase. The invention also relates to copolymers that comprise the furandicarboxylic acid monomers and derivatives thereof, processes for the formation of the copolymers and uses for the copolymers.

Abstract translation: 本发明涉及通过5-羟甲基糠醛的多步生物催化氧化反应形成呋喃二羧酸（FDCA），特别是2,5-呋喃二羧酸（2,5-FDCA）及其单酯和二酯衍生物的方法 （HMF），使用例如选自黄嘌呤氧化还原酶（XOR），半乳糖氧化酶变体M3-5，醛脱氢酶和/或酮还原酶的酶。 本发明还涉及包含呋喃二羧酸单体及其衍生物的共聚物，共聚物的形成方法和共聚物的用途。