公开(公告)号：WO2019134984A1

公开(公告)日：2019-07-11

申请号：PCT/EP2019/050194

申请日：2019-01-07

Applicant: CELON PHARMA S.A.

Inventor： MACH, Mateusz ,  DZIDA, Radoslaw ,  SMUGA, Damian ,  STELMACH, Filip ,  MATLOKA, Mikolaj ,  BAZYDLO, Katarzyna ,  DUBIEL, Krzysztof ,  WIECZOREK, Maciej ,  PIECZYKOLAN, Jerzy

IPC: A61P3/10 ,  C07C57/42 ,  C07C57/60 ,  A61K31/192

CPC classification number: A61P3/10 ,  C07B2200/07 ,  C07C59/64

Abstract: A compound of the formula (I)wherein R represents a straight or branched, primary or secondary acyclic hydrocarbyl C3–C15 group, which can be saturated or unsaturated, or a straight or branched, primary or secondary acyclic hydrocarbyl C3–C15 group, which can be saturated or unsaturated and wherein one or more of hydrogen atoms is replaced with fluorine atom; X represents hydrogen atom or halogen atom,and* denotes chiral center, and salts thereof. The compound is useful for the treatment of diseases mediated by GPR40, in particular type II diabetes. (I)