公开(公告)号：WO2023277996A1

公开(公告)日：2023-01-05

申请号：PCT/US2022/025564

申请日：2022-04-20

Applicant: CLEARPOINT NEURO, INC.

Inventor： ZAGORCHEV, Lyubomir Georgiev ,  OSSWALD, Christian Richard ,  GALLO, Nicolas ,  VIJ, Kamal

IPC: A61B18/20 ,  A61B90/00

Abstract: Methods and systems that provide quantitative assessments of in vivo thermal treatments, such as ablations, during image-guided surgeries using a high-resolution pre-operative MRI image segmented with a shape constrained and deformable mesh representations of brain structures and generating 3-D visualizations of thermally treated volumes during the thermal treatment that can provide near real time visual and quantitative feedback to a clinician.

公开(公告)号：WO2022197380A1

公开(公告)日：2022-09-22

申请号：PCT/US2022/014673

申请日：2022-02-01

Applicant: CLEARPOINT NEURO, INC.

Inventor： ZAGORCHEV, Lyubomir Georgiev ,  RUBIO, Roberto Felipe ,  KELLY, Edwin

IPC: A61B17/34 ,  A61B34/10 ,  A61B90/00 ,  A61N1/05 ,  A61N1/36 ,  G06T17/20

Abstract: Methods and systems that identify an intrabody orientation of a directional medical device, such as a deep brain stimulation (DBS) lead, use a mesh model. The mesh model is a shape-constrained trained model of fused post-operative MRI and CT image data of brains from a set of patients defined by intensity of artifact patterns corresponding to a passive orientation marker on a physical device.