Abstract:
Antimicrobial ophthalmic devices such as contact lenses, ocular inserts, ocular bandages, and intraocular lenses comprise a hydrogel and an antimicrobially-effective amount of epsilon polylysine non-covalently attached to the hydrogel.
Abstract:
Silicone hydrogel contact lenses are packaged in a packaging solution including an ophthalmically-acceptable concentration of a surfactant to provide a contact lens having a lower coefficient of friction compared to a control lens that is not packaged in the surfactant. The surfactant is a poly(ethylene oxide) (PEO)-containingsurfactant having a molecular weight of up to about 6,000 daltons, or is an alkyl aryl-containing surfactant, or is both an alkyl aryl and PEO-containing surfactant having a molecular weight of up to about 6,000 daltons. Methods of manufacturing silicone hydrogel contact lenses are also described.
Abstract:
A sealed contact lens package contains a sterile, unworn contact lens and a contact lens packaging solution comprising epsilon polylysine (εPLL). The εPLL protects the contact lens from microbial contamination caused by handling the lens when it is removed from its package.
Abstract:
Contact lenses comprising an ionic component are packaged with a beneficial cationic agent in a temperature-sensitive packaging solution and/or a low ionic strength packaging solution.