公开(公告)号：WO2018140723A1

公开(公告)日：2018-08-02

申请号：PCT/US2018/015445

申请日：2018-01-26

申请人： CROHN'S AND COLITIS FOUNDATION OF AMERICA

发明人： KUGATHASAN, Subra ,  DENSON, Lee A. ,  WALTERS, Thomas D. ,  KIM, Mi-Ok ,  STEPHENS, Michael ,  BALDASSANO, Robert ,  MARKOWITZ, James ,  ARONOW, Bruce J. ,  GIBSON, Greg ,  HYAMS, Jeffrey S. ,  DUBINSKY, Marla C. ,  MARIGORTA, Urko

IPC分类号： C07H21/00 ,  C12Q1/02 ,  C12Q1/68 ,  C40B30/00 ,  G01N33/48 ,  G01N33/53

CPC分类号： C12Q1/6883 ,  C12Q2600/118 ,  C12Q2600/158 ,  C40B30/00 ,  G01N33/48 ,  G01N33/6854 ,  G01N33/6893 ,  G01N2800/065 ,  G01N2800/50

摘要： Provided herein is a method for identifying patients at risk for suffering complications from pediatric Crohn's disease, and methods of treating those patients to prevent the development of penetrating complications.