COMPOSITION AND METHODS OF GENOME EDITING OF B CELLS
    1.
    发明申请
    COMPOSITION AND METHODS OF GENOME EDITING OF B CELLS 审中-公开
    B细胞的基因组编辑和基因组编辑方法

    公开(公告)号:WO2017176806A1

    公开(公告)日:2017-10-12

    申请号:PCT/US2017/026011

    申请日:2017-04-04

    IPC分类号: C12N5/0781 C12N15/90

    摘要: The present invention provides methods compositions and methods of preparing autologous (or allogeneic) B cells that secrete a therapeutic monoclonal antibody of interest or B cells with an altered function.

    摘要翻译: 本发明提供了制备分泌感兴趣的治疗性单克隆抗体或具有改变的功能的B细胞的自体(或同种异体)B细胞的方法组合物和方法。