公开(公告)号：WO2021108464A1

公开(公告)日：2021-06-03

申请号：PCT/US2020/062109

申请日：2020-11-24

Applicant: DANISCO US INC.

Inventor： QI, Min ,  ZHU, Quinn Qun ,  WANG, Jamie Yehong

IPC: C12N15/81 ,  C12P7/06 ,  C12R1/865 ,  C12P1/02 ,  C07K14/395

Abstract: Described are compositions and methods relating to modified yeast that over-express MIG transcriptional regulator polypeptides. The yeast produces a deceased amount of acetate compared to parental cells. Such yeast is particularly useful for large-scale ethanol production from starch substrates where acetate in an undesirable end product.

公开(公告)号：WO2021022097A1

公开(公告)日：2021-02-04

申请号：PCT/US2020/044359

申请日：2020-07-30

Applicant: DANISCO US INC

Inventor： BEMENT, Courtney ,  MACOOL, Daniel Joseph ,  WANG, Yehong Jamie ,  ZHU, Quinn Qun

IPC: C12N1/18 ,  C12N9/04 ,  C12P7/06

Abstract: Described are compositions and methods relating to modified yeast that over-expresses Adh5p and harbor a heterologous phosphoketolase pathway. The yeast demonstrates increased ethanol production from glucose compared to parental cells. Such yeast is particularly useful for large-scale ethanol production from starch substrates.

公开(公告)号：WO2020069063A1

公开(公告)日：2020-04-02

申请号：PCT/US2019/053061

申请日：2019-09-26

Applicant: DANISCO US INC

Inventor： CHEN, Zhongqiang ,  QI, Min ,  TAO, Luan ,  ZHU, Quinn Qun

IPC: C07K14/395 ,  C12N9/00 ,  C12P7/06

Abstract: Described are compositions and methods relating to modified yeast that over-express the glycerol-deficient suppressor, GDS1. The yeast produces an increased amount of ethanol and a deceased amount of acetate compared to parental cells. Such yeast is particularly useful for large-scale ethanol production from starch substrates where acetate in an undesirable end product.

公开(公告)号：WO2018176021A1

公开(公告)日：2018-09-27

申请号：PCT/US2018/024222

申请日：2018-03-24

Applicant: DANISCO US INC

Inventor： MACOOL, Daniel Joseph ,  TEUNISSEN, Paula Johanna Maria ,  WANG, Yehong Jamie ,  YOON, Hyeryoung ,  ZHU, Quinn Qun

IPC: C12P7/06

CPC classification number: C12P7/06 ,  Y02E50/17

Abstract: Described are compositions and methods relating to the over-expression of sugar transporter-like polypeptides to reduce the amount of glycerol and acetate produced by modified yeast having an exogenous pathway that cause it to produce more ethanol and acetate than its parental yeast.

公开(公告)号：WO2023076323A1

公开(公告)日：2023-05-04

申请号：PCT/US2022/047796

申请日：2022-10-26

Applicant: DANISCO US INC.

Inventor： BEMENT, Courtney ,  CHEN, Zhongqiang ,  FAN, Xiaochun ,  MACOOL, Daniel Joseph ,  QI, Min ,  WANG, Yehong Jamie ,  XUE, Zhixiong ,  ZHU, Quinn Qun

IPC: C12N9/22 ,  C07K14/395 ,  C12N15/81 ,  C12P7/04 ,  C12P7/06

Abstract: Described are compositions and methods relating to modified yeast with disrupted RSF2 or TDA9 genes. The yeast produces a decreased amount of acetate compared to otherwise identical parental cells. Such yeast is particularly useful for large-scale ethanol production from starch substrates where acetate is an undesirable end product.

公开(公告)号：WO2019173217A1

公开(公告)日：2019-09-12

申请号：PCT/US2019/020551

申请日：2019-03-04

Applicant: DANISCO US INC

Inventor： ZHU, Quinn Qun ,  TEUNISSEN, Paula Johanna Maria

IPC: C12N9/12 ,  C12N9/02 ,  C12N15/62

Abstract: Described are compositions and methods relating to yeast expressing glycerol dehydrogenase and dihydroxyacetone kinase polypeptides in combination with an exogenous phosphoketolase pathway, as well as to bifunctional glycerol dehydrogenase-dihydroxyacetone kinase fusion polypeptides, and their various and combined uses in starch hydrolysis processes for alcohol production.

公开(公告)号：WO2019173204A1

公开(公告)日：2019-09-12

申请号：PCT/US2019/020526

申请日：2019-03-04

Applicant: DANISCO US INC

Inventor： QI, Min ,  TEUNISSEN, Paula Johanna Maria ,  ZHU, Quinn Qun

IPC: C12N15/81

Abstract: Described are compositions and methods relating to modified yeast that over-express polyadenylate-binding protein (PAB1). The yeast produces a deceased amount of acetate compared to parental cells. Such yeast is particularly useful for large-scale ethanol production from starch substrates where acetate in an undesirable end product.

公开(公告)号：WO2021150911A1

公开(公告)日：2021-07-29

申请号：PCT/US2021/014641

申请日：2021-01-22

Applicant: DANISCO US INC

Inventor： CHEN, Zhongqiang ,  WANG, Yehong Jamie ,  ZHU, Quinn Qun

IPC: C12N1/18 ,  C12N15/63 ,  C12P7/02 ,  C12P7/06 ,  C07K14/395 ,  C12N15/81 ,  C12R2001/865

Abstract: Described are compositions and methods relating to modified yeast that overexpresses the J-protein, JID1. The yeast produces an increased amount of ethanol compared to otherwise identical parental cells. Such yeast is particularly useful for large-scale ethanol production from starch substrates.

公开(公告)号：WO2020186254A1

公开(公告)日：2020-09-17

申请号：PCT/US2020/022853

申请日：2020-03-14

Applicant: DANISCO US INC

Inventor： KRASLEY, Elizabeth A. ,  CHEN, Zhongqiang ,  MAGGIO-HALL, Lori Ann ,  ZHU, Quinn Qun

IPC: C12N15/81 ,  C12P7/06 ,  C07K14/395

Abstract: Described are compositions and methods relating to modified yeast that over-express fumarate-succinate transporter. The yeast produces an increased amount of ethanol and decreased amount of acetate compared to parental cells. Such yeast is particularly useful for large-scale ethanol production from starch substrates where acetate is an undesired by-product.

公开(公告)号：WO2020186224A1

公开(公告)日：2020-09-17

申请号：PCT/US2020/022777

申请日：2020-03-13

Applicant: DANISCO US INC

Inventor： MACOOL, Daniel Joseph ,  ZHU, Quinn Qun

IPC: C07K14/395 ,  C12N9/04 ,  C12P7/06

Abstract: Described are compositions and methods relating to modified yeast that over-express cytochrome B2. The yeast produces an increased amount of alcohol compared to parental cells. Such yeast is particularly useful for large-scale ethanol production from starch substrates.