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公开(公告)号：WO2023091878A1
公开(公告)日：2023-05-25
申请号：PCT/US2022/079687
申请日：2022-11-11
申请人： DANISCO US INC.
发明人： MA, Zhen , FRISCH, Ryan , PAUL, Brian , DOIG, Steven
摘要： Certain embodiments of the disclosure are related to recombinant Bacillus strains comprising enhanced protein productivity phenotypes, compositions and methods for constructing such recombinant Bacillus cells, and the like. The recombinant Bacillus strains described herein are particularly useful for the enhanced production of proteins of interest when grown/cultivated/fermented under suitable conditions.
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公开(公告)号：WO2023076323A1
公开(公告)日：2023-05-04
申请号：PCT/US2022/047796
申请日：2022-10-26
申请人： DANISCO US INC.
发明人： BEMENT, Courtney , CHEN, Zhongqiang , FAN, Xiaochun , MACOOL, Daniel Joseph , QI, Min , WANG, Yehong Jamie , XUE, Zhixiong , ZHU, Quinn Qun
IPC分类号： C12N9/22 , C07K14/395 , C12N15/81 , C12P7/04 , C12P7/06
摘要： Described are compositions and methods relating to modified yeast with disrupted RSF2 or TDA9 genes. The yeast produces a decreased amount of acetate compared to otherwise identical parental cells. Such yeast is particularly useful for large-scale ethanol production from starch substrates where acetate is an undesirable end product.
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公开(公告)号：WO2022197810A1
公开(公告)日：2022-09-22
申请号：PCT/US2022/020560
申请日：2022-03-16
申请人： DANISCO US INC
摘要： The present disclosure relates to variant lipolytic enzymes, more particularly variant lipolytic enzymes that have improved stability and/or improved hydrolytic activity on a polyester. Such variant lipolytic enzymes find use in the degradation of polyesters, such as polyethylene terephthalate. Also provided are compositions and methods related to such variant lipolytic enzymes.
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公开(公告)号：WO2022133068A1
公开(公告)日：2022-06-23
申请号：PCT/US2021/063768
申请日：2021-12-16
申请人： DANISCO US INC
发明人： LASSILA, Jonathan , LAY, Cliff , SUNUX, Sergio Anibal , WEI, Wei
摘要： Disclosed herein are compositions and methods for preventing, reducing, or removing malodor and microbial growth from liquid solutions, as well as from surfaces, such as fabrics, textiles or hard surfaces.
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公开(公告)号：WO2022115503A1
公开(公告)日：2022-06-02
申请号：PCT/US2021/060679
申请日：2021-11-24
发明人： ESTELL, David , POWER, Scott D. , ZHU, Quinn Q. , FAN, Xiaochun , HONG, Seung-Pyo , CAIMI, Perry , BENDEZU, Felipe O. , XUE, Zhixiong
IPC分类号： A61K39/215 , C07K14/165
摘要： Provided herein, inter alia, are recombinant Yarrowia cells comprising a nucleic acid encoding a viral protein or a fragment thereof for use in the treatment and prevention of viral disease as well as methods for making and using the same.
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公开(公告)号：WO2021173974A1
公开(公告)日：2021-09-02
申请号：PCT/US2021/019876
申请日：2021-02-26
发明人： MATEBOER, Aart , TRUMBULL, Amber
IPC分类号： A23K20/189
摘要： Engineered robust high Tm-phytase clade polypeptides and fragments thereof are described herein. Also described are methods of making such engineered robust high Tm-phytase clade and fragments thereof and use thereof in enhancing animal performance.
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公开(公告)号：WO2021163439A1
公开(公告)日：2021-08-19
申请号：PCT/US2021/017800
申请日：2021-02-12
摘要： The present invention relates to flavor stabilized beers and to methods of making flavor stabilized beers. More specifically, the instant disclosure provides methods and compositions for the production of flavor stabilized beer having low riboflavin using modified yeast to ferment a wort.
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公开(公告)号：WO2021142057A1
公开(公告)日：2021-07-15
申请号：PCT/US2021/012409
申请日：2021-01-07
申请人： DANISCO US INC
发明人： MIASNIKOV, Andrei , SHARMA, Vivek
IPC分类号： C12P7/10 , C12N9/48 , C12N9/58 , C12Y202/01001 , C12Y304/21 , C12Y304/2101 , C12Y304/23
摘要： The instant disclosure is generally related to microbial fermentation, grain processing and ethanol production. Certain embodiments of the disclosure are therefore related to starch-containing materials and the microbial fermentation of such starch-containing materials for the production ethanol. More particularly, certain embodiments are related to novel protease mixtures comprising an aspartic protease and a serine protease for use in processing such starch-containing materials in starch to ethanol fermentation processes described herein.
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公开(公告)号：WO2021086605A1
公开(公告)日：2021-05-06
申请号：PCT/US2020/055481
申请日：2020-10-14
申请人： DANISCO US INC
发明人： AUKEMA, Kelly Gardner , DHALIWAL, Rajdeep S. , GUO, Feng , HENG, Meng Hong , HOFFMANN, Katherine , LATONE, Jacob Andrew , WACKETT, Lawrence Philip , WHITED, Gregory M.
IPC分类号： C02F3/34 , C02F1/70 , C02F101/18 , C02F103/42
摘要： The present disclosure is generally related to the fields of biology, inorganic chemistry, organic chemistry, molecular biology, enzymology, chlorinated water treatment processes and the like. More particularly, certain embodiments are related to reducing cyanuric acid concentrations in aqueous liquids, such as chlorinated swimming pool water, chlorinated hot tub water and the like.
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公开(公告)号：WO2021041361A1
公开(公告)日：2021-03-04
申请号：PCT/US2020/047715
申请日：2020-08-25
申请人： DANISCO US INC
发明人： JÄRVINEN, Juho , KOIVIKKO, Hannu , KUUSISTO, Jyrki , MENTUNEN, Tero Tuomas , NURMI, Juha , SÄRELÄ, Pertti Matias , SIITONEN, Jani , WHITED, Gregory M.
摘要： Compositions and methods are provided for producing crystalline forms of organic acids or salts or lactones thereof from an aqueous solution. More specifically, methods are provided for producing a crystalline form of a salt of mevalonic acid (also referred to as X-MVA) from an aqueous solution, comprising subjecting the aqueous solution comprising said X-MVA to a purification step to produce a purified solution and crystallizing said X-MVA from said purified solution by water solvent crystallization. Methods are also provided for producing mevalonolactone from an aqueous solution comprising X-MVA, comprising subjecting the aqueous solution comprising said X-MVA to cation exchange thereby converting said aqueous solution comprising X-MVA to an aqueous solution comprising mevalonolactone (MVL). Methods are also provided for producing mevalonolactone monohydrate crystals.
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