公开(公告)号：WO2022011261A2

公开(公告)日：2022-01-13

申请号：PCT/US2021/041088

申请日：2021-07-09

Applicant: DETECT, INC.

Inventor： GLANTZ, Spencer ,  ROTHBERG, Jonathan, M. ,  KEMBLE, Henry ,  SABINA, Jeff ,  JARAMILLO-RIVERI, Sebastian

IPC: C12Q1/6853 ,  C07H21/04 ,  C12Q1/6832 ,  C12Q1/6818 ,  C12Q1/6844 ,  C12Q1/6846 ,  C12Q1/6888 ,  C12Q2600/158

Abstract: Aspects of the disclosure relate to compositions and methods for amplifying and/or detecting one or more target nucleic acid sequences (e.g., a nucleic acid sequence of one or more pathogens) in a biological sample obtained from a subject. In some embodiments, the pathogens are viral, bacterial, fungal, parasitic, or protozoan pathogens, such as SARS-CoV-2 or an influenza virus. In some embodiments, the methods comprise isothermal amplification of a target nucleic acid and subsequent detection of the amplification products.