公开(公告)号：WO2012023031A3

公开(公告)日：2012-04-26

申请号：PCT/IB2011001905

申请日：2011-08-18

Applicant: DH TECHNOLOGIES DEV PTE LTD ,  GUNA MIRCEA ,  COLLINGS BRUCE

Inventor： GUNA MIRCEA ,  COLLINGS BRUCE

IPC: H01J49/02

CPC classification number: H01J49/0031 ,  H01J49/025 ,  H01J49/06 ,  H01J49/061

Abstract: A mass spectrometer system can include a mass analyzer operable to mass transmit streams of ions to a detector in a mass dependent fashion for measurement of ion flux intensity. An ion attenuator can be located in the extraction region between the mass analyzer and detector, downstream of the mass analyzer, and can be operable to provide selective attenuation of the ion beam by attenuating ion flux intensity also in mass dependent fashion. Higher concentration ions can be selected and attenuated, while other lower concentration ions can be left unattenuated. Different ions can be attenuated to different degrees. Locating the ion attenuator downstream of the mass analyzer so that the ion beam is already mass differentiated when attenuated can avoid mass discriminatory effects associated with ion beam attenuators. Selective attenuation of only certain ions but not others can extend the dynamic range of the detector without necessarily sacrificing detector sensitivity.

Abstract translation: 质谱仪系统可以包括质量分析器，可以以质量依赖的方式将离子流质量传递到检测器，以测量离子通量强度。 离子衰减器可以位于质量分析器和检测器之间的质量分析器下游的提取区域中，并且可以通过以质量依赖的方式衰减离子通量强度来提供离子束的选择性衰减。 可以选择和减弱较高浓度的离子，而其他较低浓度的离子可以保持不衰减。 不同的离子可以衰减到不同的程度。 将质子分析仪下游的离子衰减器定位，使得当衰减时离子束已经被质量区分，可以避免与离子束衰减器相关的质量鉴别效应。 只有某些离子而不是其他离子的选择性衰减才能扩展检测器的动态范围，而不必牺牲检测器灵敏度。