公开(公告)号：WO2012129413A1

公开(公告)日：2012-09-27

申请号：PCT/US2012/030134

申请日：2012-03-22

Applicant: DRAEGER MEDICAL SYSTEMS, INC. ,  CHEN, Yu ,  ZHANG, Zhe

Inventor： CHEN, Yu ,  ZHANG, Zhe

IPC: A61B5/0452 ,  G06K9/00 ,  G01D3/028

CPC classification number: A61B5/0456 ,  A61B5/04012 ,  A61B5/0452 ,  A61B5/0472 ,  A61B5/7221

Abstract: An apparatus and method for determining a signal quality of an input signal representing a repetitious phenomena derived from at least one sensor connected to a patient is provided. A detector receives the input signal and determines data representing the repetitious phenomena from the input signal for use in determining at least one patient parameter. A measurement processor is electrically coupled to the detector that determines a first signal quality value by identifying at least one feature of the repetitious phenomena data and compares the at least one feature of a first set of the determined repetitious phenomena data with a second set of the determined repetitious phenomena data to determine a feature variability value and using the feature variability value to determine a stability value representative of the quality of the input signal.

Abstract translation: 提供了一种用于确定表示从连接到患者的至少一个传感器导出的重复现象的输入信号的信号质量的装置和方法。 检测器接收输入信号并且确定表示来自输入信号的重复现象的数据，以用于确定至少一个患者参数。 测量处理器电耦合到检测器，其通过识别重复现象数据的至少一个特征来确定第一信号质量值，并将确定的重复现象数据的第一组的至少一个特征与第二组 确定的重复现象数据以确定特征变异性值并使用特征变异性值来确定表示输入信号质量的稳定性值。

公开(公告)号：WO2012149207A1

公开(公告)日：2012-11-01

申请号：PCT/US2012/035282

申请日：2012-04-26

Applicant: DRAEGER MEDICAL SYSTEMS, INC. ,  CHEN, Yu ,  EL-GHOUCH, Mohamad, M. ,  ZHANG, Zhe

Inventor： CHEN, Yu ,  EL-GHOUCH, Mohamad, M. ,  ZHANG, Zhe

IPC: A61B5/0452 ,  A61B5/022

CPC classification number: A61B5/02225 ,  A61B5/02028 ,  A61B5/02116 ,  A61B5/04012 ,  A61B5/0408 ,  A61B5/04525 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/0472 ,  G06F19/00

Abstract: Disclosed is a method for implementation by one or more data processors including acquiring noninvasive blood pressure data using an inflatable cuff applied around a portion of a patient by inflating the cuff to a pressure above the patient's systolic blood pressure, and detecting a first oscillation pulse within the cuff during a deflation step. The method also includes acquiring electrocardiogram (ECG) data from the patient by detecting an ECG waveform corresponding to a first heartbeat using an ECG lead coupled to the patient, classifying the ECG waveform as normal or not normal, aligning, the first oscillation pulse to the ECG waveform corresponding to the first heartbeat if the ECG waveform is classified normal or rejecting the first oscillation pulse if the ECG waveform is classified not normal, and calculating the blood pressure using the aligned first oscillation pulse. Related apparatus, systems, methods and/or articles are described.

Abstract translation: 公开了一种用于由一个或多个数据处理器实现的方法，包括使用通过将袖带膨胀到高于患者的收缩压的压力的周围的患者的一部分周围施加的可膨胀的袖带来获取无创血压数据，并且检测第一振荡脉冲 在通缩步骤期间的袖口。 该方法还包括通过使用耦合到患者的ECG导联检测对应于第一心跳的ECG波形来从患者获取心电图（ECG）数据，将ECG波形分类为正常或不正常，将第一振荡脉冲对准 如果ECG波形被分类为正常，则将ECG波形对应于第一心跳，如果ECG波形被分类为不正常则排除第一振荡脉冲，并且使用对准的第一振荡脉冲计算血压。 描述了相关装置，系统，方法和/或制品。

公开(公告)号：WO2013162613A1

公开(公告)日：2013-10-31

申请号：PCT/US2012/035647

申请日：2012-04-27

Applicant: DRAEGER MEDICAL SYSTEMS, INC. ,  LALL, Carolyn Anjali ,  CHEN, Yu

Inventor： LALL, Carolyn Anjali ,  CHEN, Yu

IPC: A61B5/0452 ,  G06K9/00 ,  A61N1/08

CPC classification number: A61B5/7217 ,  A61B5/0006 ,  A61B5/04017 ,  A61B5/044 ,  A61B5/0452 ,  A61B5/04525 ,  A61B5/7246 ,  A61N1/37 ,  A61N1/3706

Abstract: Data is received characterizing an electrocardiogram (ECG) measured from a patient having a pacemaker. The pacemaker can intermittently provide a pace to a heart of the patient. By comparing at least a portion of the received data to a template a pace pulse can be detected from at least a portion of the received data. The template comprises one or more pace pulses measured from the patient. The template is modified, at least in part, by the detected pace pulse to update the template. Data characterizing the detected pace pulse is provided. Related apparatus, systems, techniques and articles are also described.

Abstract translation: 数据被接收，表征从具有起搏器的患者测量的心电图（ECG）。 起搏器可以间断地为患者的心脏提供一个步伐。 通过将接收到的数据的至少一部分与模板进行比较，可以从接收到的数据的至少一部分检测起搏脉冲。 模板包括从患者测量的一个或多个起搏脉冲。 该模板至少部分地通过检测到的起搏脉冲进行修改，以更新模板。 提供表征检测到的起搏脉冲的数据。 还描述了相关设备，系统，技术和物品。

公开(公告)号：WO2013036307A1

公开(公告)日：2013-03-14

申请号：PCT/US2012/041386

申请日：2012-06-07

Applicant: DRAEGER MEDICAL SYSTEMS, INC. ,  ZHENG, Ling ,  CHEN, Yu

Inventor： ZHENG, Ling ,  CHEN, Yu

IPC: A61B5/04 ,  G06K9/00

CPC classification number: A61B5/04017 ,  A61B5/7203 ,  A61B5/725 ,  G06K9/00503

Abstract: A system includes a low pass-filter and a Savitzky-Golay filter. The low-pass filter receives and processes a first electrocardiogram signal. The filter removes at least the high frequency components of the first electrocardiogram signal. The Savitzky-Golay filter estimates a baseline variation of the first electrocardiogram signal from the filtered first electrocardiogram signal. Related apparatus, systems, techniques and articles are also described.

Abstract translation: 系统包括低通滤波器和Savitzky-Golay滤波器。 低通滤波器接收并处理第一心电图信号。 滤波器至少去除第一心电图信号的高频分量。 Savitzky-Golay滤波器估计来自滤波的第一心电图信号的第一心电图信号的基线变化。 还描述了相关设备，系统，技术和物品。

公开(公告)号：WO2012145571A1

公开(公告)日：2012-10-26

申请号：PCT/US2012/034354

申请日：2012-04-20

Applicant: DRAEGER MEDICAL SYSTEMS, INC. ,  ZHENG, Ling ,  CHEN, Yu

Inventor： ZHENG, Ling ,  CHEN, Yu

IPC: A61B5/04 ,  A61B5/0428

CPC classification number: A61B5/7203 ,  A61B5/04017 ,  A61B5/0428 ,  A61B5/0472 ,  H04B1/109

Abstract: A patient monitoring device and method that determines and monitors at least one patient parameter is provided. A configuration processor generates configuration information in response to a first input signal and an adaptive notch filter receives a second input signal. The second input signal includes a signal of interest and an interference signal in a predetermined frequency range. The adaptive notch filter automatically estimates the interference signal within the second input signal based on a filter parameter and removes the estimated interference signal from the second input signal to generate a target signal. A step processor is electrically coupled between the configuration processor and the adaptive notch filter and sets a value of the filter parameter based on the configuration information, wherein the adaptive notch filter uses the filter parameter to reduce a ringing artifact on the target signal below a threshold level.

Abstract translation: 提供了确定和监视至少一个患者参数的患者监测装置和方法。 配置处理器响应于第一输入信号产生配置信息，并且自适应陷波滤波器接收第二输入信号。 第二输入信号包括感兴趣的信号和预定频率范围内的干扰信号。 自适应陷波滤波器基于滤波器参数自动估计第二输入信号内的干扰信号，并从第二输入信号中去除估计的干扰信号以产生目标信号。 步进处理器电耦合在配置处理器和自适应陷波滤波器之间，并且基于配置信息设置滤波器参数的值，其中自适应陷波滤波器使用滤波器参数来减少低于阈值的目标信号上的振铃伪影 水平。

公开(公告)号：WO2020077266A1

公开(公告)日：2020-04-16

申请号：PCT/US2019/055940

申请日：2019-10-11

Applicant: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES ,  SINGEC, Ilyas ,  CHEN, Yu ,  SIMEONOV, Anton

Inventor： SINGEC, Ilyas ,  CHEN, Yu ,  SIMEONOV, Anton

IPC: C12N5/00 ,  C12N5/0775 ,  C12N5/0735 ,  C12N5/074 ,  C12N2501/40 ,  C12N5/0018 ,  C12N5/0606 ,  C12N5/0662 ,  C12N5/0696

Abstract: Compositions and methods useful for culturing mammalian cells, tissues and/or organs are provided. The compositions contain Chroman 1 or its derivatives, may further include Emricasan or its derivatives, and may further include one or both of trans-ISRIB and polyamines. The compositions may be formulated as media additives, media concentrates or working media. The compositions and methods may be used to culture stem cells, progenitor cells, differentiated cells, isolated primary cells, secondary cells, immortalized cells, cell line cells, germline cells, somatic cells, or modified cells, including genetically modified cells. The compositions and methods may be used to culture, preserve or maintain cells, tissues, organs parts or organs, grow embryoid bodies, embryos, organs or organ parts.

公开(公告)号：WO2020024091A1

公开(公告)日：2020-02-06

申请号：PCT/CN2018/097725

申请日：2018-07-30

Applicant: DOW GLOBAL TECHNOLOGIES LLC ,  CHEN, Yu ,  FENG, Yanli ,  GUO, Kunpeng ,  ZHENG, Chen ,  FENG, Shaoguang ,  CHEN, Huan ,  WAN, Xiaohuan ,  TANG, Qiqi

Inventor： CHEN, Yu ,  FENG, Yanli ,  GUO, Kunpeng ,  ZHENG, Chen ,  FENG, Shaoguang ,  CHEN, Huan ,  WAN, Xiaohuan ,  TANG, Qiqi

IPC: C08G18/22 ,  C08G59/22

Abstract: A polymer resin composition free of solvent and adapted for in situ curing including : (a) at least one epoxy resin compound; (b) at least one isocyanate compound; and (c) a catalyst system including a combination of at least one primary catalyst and at least one secondary catalyst; wherein the primary catalyst includes (ci) at least one organoantimony catalyst; and wherein the secondary catalyst includes (cii) a nitrogen-containing catalyst; and a process for preparing the above composition.

公开(公告)号：WO2018112738A1

公开(公告)日：2018-06-28

申请号：PCT/CN2016/111024

申请日：2016-12-20

Applicant: INTEL CORPORATION ,  CHEN, Yu ,  DU, Jianghong

Inventor： CHEN, Yu ,  DU, Jianghong

IPC: G06F1/00

Abstract: In one example, a system for managing power states can include a processor to detect a power state transition operation and detect historical callback information for each of a plurality of drivers of the system. The processor can also sort the plurality of drivers into a plurality of driver groups based on the historical callback information and execute the power state transition operation by transmitting a plurality of power state instructions for each driver to a plurality of processors based on the plurality of driver groups.

公开(公告)号：WO2013046020A1

公开(公告)日：2013-04-04

申请号：PCT/IB2012/002019

申请日：2012-09-14

Applicant: ALCATEL LUCENT ,  CHEN, Yu ,  ZOU, Jialin ,  PALAT, Sudeep

Inventor： CHEN, Yu ,  ZOU, Jialin ,  PALAT, Sudeep

IPC: H04W72/00 ,  H04W4/06

CPC classification number: H04L5/0037 ,  H04L5/0094 ,  H04L61/2069 ,  H04W4/70 ,  H04W8/186 ,  H04W28/06 ,  H04W72/042 ,  H04W72/12

Abstract: The invention relates to a method of implementing resource scheduling for MTC devices, the base station assigns multiple machine type communication (MTC) devices to a group, and allocates to each device a sequence number of the group respectively, informs each corresponding device of the sequence number of the device, allocates a resource set for the group, and transmits indication information, indicating the resource set, to each device via broadcast signaling, wherein, the sequence number is used to indicate the resource, in the resource set, used by the device. A MTC device determines the resource, in the resource set, used by the device based on the sequence number. The embodiment of the invention can save the overhead of MTC resource scheduling.

Abstract translation: 本发明涉及一种实现MTC设备资源调度的方法，基站向组分配多机类型通信（MTC）设备，分别向每个设备分配该组的序列号，通知每个对应的设备序列 为该组分配资源集，通过广播信令向每个设备发送指示资源集的指示信息，其中，序列号用于指示资源集合中使用的资源 设备。 MTC设备基于序列号确定设备使用的资源集中的资源。 本发明的实施例可以节省MTC资源调度的开销。

公开(公告)号：WO2013036755A1

公开(公告)日：2013-03-14

申请号：PCT/US2012/054138

申请日：2012-09-07

Applicant: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH ,  CHI, Ping ,  CHEN, Yu ,  SAWYERS, Charles ,  ALLIS, C., David

Inventor： CHI, Ping ,  CHEN, Yu ,  SAWYERS, Charles ,  ALLIS, C., David

IPC: C07K16/00 ,  C12P21/08

CPC classification number: C07K16/18 ,  C07K2317/34 ,  C12Q1/6886 ,  C12Q2600/158 ,  G01N33/57446 ,  G01N2333/4706 ,  G01N2800/52

Abstract: The present invention provides monoclonal antibodies that bind to the ETV1 protein. The present invention also provides various methods and compositions relating to provided antibodies. For example, the present invention provides compositions, including pharmaceutical compositions, comprising provided antibodies, or fragments or mimics thereof. The present invention provides various therapeutic and/or diagnostic methods of using provided antibodies and/or compositions.

Abstract translation: 本发明提供了结合ETV1蛋白的单克隆抗体。 本发明还提供了与提供的抗体相关的各种方法和组合物。 例如，本发明提供包括提供的抗体或其片段或模拟物的组合物，包括药物组合物。 本发明提供使用提供的抗体和/或组合物的各种治疗和/或诊断方法。