公开(公告)号：WO1997009006A1

公开(公告)日：1997-03-13

申请号：PCT/US1996013907

申请日：1996-08-30

Applicant: EMORY UNIVERSITY

Inventor： EMORY UNIVERSITY ,  WAKSMAN, Ron ,  KING, Spencer, B. ,  SCOTT, Neal, A.

IPC: A61F02/04

CPC classification number: A61F2/07 ,  A61F2/90 ,  A61F2/95 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2250/0067 ,  A61L27/54 ,  A61L2300/412 ,  A61L2300/416 ,  A61L2300/42 ,  A61L2300/432 ,  A61L2300/602

Abstract: This invention is an endovascular support device (10) adapted for local delivery of a therapeutic agent (50) for minimizing the rate of restenosis having a cylindrical support body (12) with an inside surface (14), an opposite outside surface (16), and at least one layer of pericardial tissue (20) covering at least a portion of at least a selected one of the inside surface (14), or the outside surface (16) of the cylindrical support body (12). At least one therapeutic agent (50) is disposed on a portion of the support device (10).

Abstract translation: 本发明是适于局部递送治疗剂（50）的血管内支持装置（10），用于使具有内表面（14），相对的外表面（16）的具有圆柱形支撑体（12）的再狭窄率最小化， 以及覆盖至少一个所述圆柱形支撑体（12）的内表面（14）或外表面（16）中的一个的至少一部分的心包组织（20）的至少一层。 至少一种治疗剂（50）设置在支撑装置（10）的一部分上。

公开(公告)号：WO1997037715A1

公开(公告)日：1997-10-16

申请号：PCT/US1997005538

申请日：1997-04-04

Applicant: NOVOSTE CORPORATION ,  EMORY UNIVERSITY

Inventor： NOVOSTE CORPORATION ,  EMORY UNIVERSITY ,  WAKSMAN, Ron ,  WELDON, Thomas, D. ,  MELOUL, Raphael, F. ,  HILLSTEAD, Richard, A. ,  ROSEN, Jonathan, J. ,  BONNOITT, George, K. ,  HALPERN, David, S. ,  LARSEN, Charles, E. ,  CROCKER, Ian, R.

IPC: A61M29/00

CPC classification number: A61M37/0069 ,  A61M25/0029 ,  A61M25/1002 ,  A61M25/1006 ,  A61M2025/0037 ,  A61M2025/0039 ,  A61M2025/004 ,  A61N5/1002 ,  A61N5/1007 ,  A61N2005/1003 ,  A61N2005/1005 ,  A61N2005/1008 ,  A61N2005/1023

Abstract: Apparatus for delivery of a treatment element (22) such as a radiation source, through a catheter (92) to a desired site in the interluminal passageways of a patient, such as the coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty. One or more treatment elements (22), such as a capsule or pellet containing radioactive material, is positionable within the lumen (144) and movable between the proximal and distal end portions under the force of liquid flowing through the lumen. Balloon membrane (256) can be used for angioplasty.

Abstract translation: 用于将诸如辐射源的治疗元件（22）（例如辐射源）递送到诸如冠状动脉的患者的椎间通道中的期望部位的用于抑制诸如可能的瘢痕组织的形成的装置 发生在球囊血管成形术后再狭窄。 一个或多个治疗元件（例如包含放射性物质的胶囊或丸粒）可定位在内腔（144）内，并可在液体流过内腔的液体力的作用下在近端部分和远端部分之间移动。 球囊膜（256）可用于血管成形术。