公开(公告)号：WO0037109A3

公开(公告)日：2000-09-14

申请号：PCT/EP9910010

申请日：1999-12-16

Applicant: EUPHAR GROUP SRL ,  CORVI MORA PAOLO

Inventor： CORVI MORA PAOLO

IPC: A61K47/12 ,  A61K31/565 ,  A61K31/568 ,  A61K47/18 ,  A61K47/32 ,  A61K47/34 ,  A61K47/36 ,  A61K47/38 ,  A61K47/40 ,  A61K47/48 ,  A61P5/00 ,  A61P5/26 ,  A61P5/38 ,  A61P15/08 ,  A61P27/02

CPC classification number: B82Y5/00 ,  A61K31/565 ,  A61K47/6951

Abstract: The present invention refers to clathrates of dehydroepiandrosterone, possibly in the form of sulphate, in a matrix consisting of a cyclodextrin and optionally comprising a co-solubilization agent, and to the corresponding pharmaceutical compositions suitable for replacement therapy for the treatment of adrenocortical insufficiency, adrenopausal disorders, hypogonadim and xerophtalmia.

Abstract translation: 本发明涉及可能以硫酸盐形式的脱氢表雄酮的包合物，其由由环糊精组成的基质和任选地包含共增溶剂，以及适用于治疗肾上腺皮质功能不全的替代疗法的相应药物组合物，肾上腺皮质激素 疾病，性腺功能减退和皮肤干燥症。