公开(公告)号：WO2019145863A1

公开(公告)日：2019-08-01

申请号：PCT/IB2019/050552

申请日：2019-01-23

Applicant: FIDIA FARMACEUTICI S.P.A.

Inventor： PASTORELLO, Andrea ,  BETTELLA, Flavio ,  GALESSO, Devis

IPC: A61K9/00 ,  A61K47/36

Abstract: Disclosed are pharmaceutical compositions in gel form comprising a hydrophilic matrix consisting of a hyaluronic acid derivative containing an amide local anaesthetic in base form.

公开(公告)号：WO2020212853A1

公开(公告)日：2020-10-22

申请号：PCT/IB2020/053530

申请日：2020-04-15

Applicant: FIDIA FARMACEUTICI S.P.A.

Inventor： BARBERA, Carlo ,  PASTORELLO, Andrea

IPC: A61K9/06 ,  A61K31/366 ,  A61K31/40 ,  A61K31/404 ,  A61P19/02 ,  A61K47/36

Abstract: The present invention relates to pharmaceutical compositions comprising mixtures of a statin and a hyaluronic acid amide derivative which are useful in the treatment of inflammation and degradation of osteoarthritic joint cartilage, in particular post-traumatic osteoarthrosis and osteoarthrosis caused by physiological joint aging, and in the treatment of other joint disorders such as rheumatoid arthritis.

公开(公告)号：WO2012110456A1

公开(公告)日：2012-08-23

申请号：PCT/EP2012/052412

申请日：2012-02-13

Applicant: FIDIA FARMACEUTICI S.p.A. ,  PASTORELLO, Andrea ,  GALESSO, Devis ,  BETTELLA, Fabio

Inventor： PASTORELLO, Andrea ,  GALESSO, Devis ,  BETTELLA, Fabio

IPC: A61K9/14 ,  A61K31/192 ,  A61K31/196 ,  A61K31/717 ,  A61K31/729 ,  A61K33/38 ,  A61P29/00 ,  A61P43/00

CPC classification number: A61K31/738 ,  A61K9/0014 ,  A61K9/146 ,  A61K31/192 ,  A61K31/196 ,  A61K31/717 ,  A61K31/728 ,  A61K31/729 ,  A61K33/38 ,  A61K45/06 ,  A61K2300/00

Abstract: The invention discloses pharmaceutical compositions in the form of a dusting powder or dry spray, possessing a high absorbent capacity, painkilling activity and wound-healing action, which compositions consist of croscarmellose sodium, a non-steroidal anti-inflammatory drug (NSAID) and hyaluronic acid, and optionally also contain other pharmacologically active substances and/or excipients. The compositions disclosed herein are suitable for use in the treatment of skin lesions wherein the presence of exudate limits wound healing and causes pain; they are therefore particularly suitable for chronic ulcerous skin lesions of various origins and burns.

Abstract translation: 本发明公开了具有高吸收能力，止痛活性和伤口愈合作用的粉剂或干喷雾形式的药物组合物，该组合物由交联羧甲纤维素钠，非甾体抗炎药（NSAID）和透明质酸 酸，并且任选地还含有其它药理活性物质和/或赋形剂。 本文公开的组合物适用于治疗皮肤病变，其中渗出液的存在限制伤口愈合并引起疼痛; 因此它们特别适用于各种起源和灼伤的慢性溃疡性皮肤病变。