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公开(公告)号：WO2016073774A3
公开(公告)日：2016-07-07
申请号：PCT/US2015059316
申请日：2015-11-05
发明人： BECK HILARY PLAKE , JAEN JUAN CARLOS , OSIPOV MAKSIM , POWERS JAY PATRICK , REILLY MAUREEN KAY , SHUNATONA HUNTER PAUL , WALKER JAMES ROSS , ZIBINSKY MIKHAIL , BALOG JAMES AARON , WILLIAMS DAVID K , MARKWALDER JAY A , SEITZ STEVEN P , CHERNEY EMILY CHARLOTTE , ZHANG LIPING , SHAN WEIFANG , GUO WEIWEI , HUANG AUDRIS
CPC分类号： A61K31/166 , A61K31/00 , A61K31/136 , A61K31/277 , A61K31/4412 , A61K31/445 , A61K31/47 , A61K31/4709 , A61K31/496 , A61K31/497 , A61K31/506 , A61K31/519 , A61K31/5377 , A61K45/06 , C07C211/45 , C07C217/80 , C07C233/10 , C07C233/59 , C07C233/60 , C07C233/65 , C07C233/74 , C07C255/50 , C07C255/58 , C07C275/30 , C07C2601/14 , C07D211/08 , C07D213/68 , C07D215/04 , C07D215/233 , C07D487/04
摘要： Compounds that modulate the oxidoreductase enzyme indoleamine 2,3- dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
摘要翻译： 本文描述了调节氧化还原酶吲哚胺-2,3-双加氧酶的化合物和含有该化合物的组合物。 还提供了这样的化合物和组合物用于治疗和/或预防由吲哚胺2,3-双加氧酶介导的各种疾病，病症和病症（包括癌症和免疫相关病症）的用途。
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公开(公告)号：WO2016073738A3
公开(公告)日：2016-07-07
申请号：PCT/US2015059271
申请日：2015-11-05
发明人： BECK HILARY PLAKE , JAEN JUAN CARLOS , OSIPOV MAKSIM , POWERS JAY PATRICK , REILLY MAUREEN KAY , SHUNATONA HUNTER PAUL , WALKER JAMES ROSS , ZIBINSKY MIKHAIL , BALOG JAMES AARON , WILLIAMS DAVID K , GUO WEIWEI
CPC分类号： A61K31/195 , A61K31/167 , A61K31/426 , A61K39/39 , A61K45/06 , A61K2039/55511 , C07C233/15 , C07C233/29 , C07C233/66 , C07C235/26 , C07C235/36 , C07C235/38 , C07C237/20 , C07C237/22 , C07C255/57 , C07C255/60 , C07C317/40 , C07C317/44 , C07C321/28 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07D207/27 , C07D213/56 , C07D213/75 , C07D231/12 , C07D239/42 , C07D277/30 , C07D295/15 , C07D295/155 , C07D309/04 , C07D309/06 , C07D317/46 , A61K2300/00
摘要： Compounds that modulate the oxidoreductase enzyme indoleamine 2,3- dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune -related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
摘要翻译： 本文描述了调节氧化还原酶吲哚胺2,3-双加氧酶的化合物和含有该化合物的组合物。 还提供了此类化合物和组合物用于治疗和/或预防由吲哚胺2,3-双加氧酶介导的各种疾病，病症和病症（包括癌症和免疫相关病症）的用途。
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