公开(公告)号：WO2022272174A1

公开(公告)日：2022-12-29

申请号：PCT/US2022/035179

申请日：2022-06-27

Applicant: GILGAMESH PHARMACEUTICALS, INC.

Inventor： KRUEGEL, Andrew Carry

IPC: A61K31/135 ,  A61P25/00 ,  A61P25/24 ,  C07C225/20 ,  C07B2200/07 ,  C07C2601/14

Abstract: Provided herein are arylcyclohexylamines and their use in the treatment of psychiatric disorders.

公开(公告)号：WO2022235927A1

公开(公告)日：2022-11-10

申请号：PCT/US2022/027862

申请日：2022-05-05

Applicant: GILGAMESH PHARMACEUTICALS, INC.

Inventor： KRUEGEL, Andrew Carry

IPC: C07D209/16 ,  A61P25/22 ,  A61P25/24 ,  A61P25/30 ,  A61K31/4045

Abstract: Novel tryptamines and methods of treating mood disorders with compounds disclosed herein. Also provided are pharmaceutical compositions that include those compounds.

公开(公告)号：WO2023028086A1

公开(公告)日：2023-03-02

申请号：PCT/US2022/041274

申请日：2022-08-23

Applicant: GILGAMESH PHARMACEUTICALS, INC.

Inventor： KRUEGEL, Andrew Carry

IPC: A61P25/18 ,  A61K31/165 ,  A61K31/403 ,  A61K31/437

Abstract: Methods of treating mood disorders with compounds disclosed herein. Also provided are pharmaceutical compositions that include those compounds.

公开(公告)号：WO2021168082A1

公开(公告)日：2021-08-26

申请号：PCT/US2021/018534

申请日：2021-02-18

Applicant: GILGAMESH PHARMACEUTICALS, INC.

Inventor： KRUEGEL, Andrew Carry ,  SPORN, Jonathan

IPC: A61K31/404 ,  A61K9/00 ,  A61K31/4045 ,  A61P25/18 ,  A61P25/24 ,  A61P25/26 ,  A61P25/30

Abstract: Methods of treating mood disorders with compounds disclosed herein. Also provided are pharmaceutical compositions that include those compounds.

公开(公告)号：WO2022226408A1

公开(公告)日：2022-10-27

申请号：PCT/US2022/026186

申请日：2022-04-25

Applicant: GILGAMESH PHARMACEUTICALS, INC.

Inventor： KRUEGEL, Andrew Carry

IPC: C07D457/08 ,  C07D457/06 ,  A61K31/48 ,  A61P25/00

Abstract: The present disclosure provides ergoline compounds and their use in treating mood disorders. Pharmaceutical compositions and methods of making various ergoline compounds are provided.

公开(公告)号：WO2022051670A1

公开(公告)日：2022-03-10

申请号：PCT/US2021/049149

申请日：2021-09-03

Applicant: GILGAMESH PHARMACEUTICALS, INC.

Inventor： KRUEGEL, Andrew Carry

IPC: C07D403/06 ,  C07F9/00 ,  A61P25/22 ,  A61P25/24 ,  A61P25/30 ,  A61K31/4045

Abstract: The present disclosure includes azetidinyl tryptamines and methods of treating psychiatric disorders with such compounds. Also provided are pharmaceutical compositions that include azetidinyl tryptamines.

公开(公告)号：WO2022192781A1

公开(公告)日：2022-09-15

申请号：PCT/US2022/020196

申请日：2022-03-14

Applicant: GILGAMESH PHARMACEUTICALS, INC.

Inventor： KRUEGEL, Andrew Carry

IPC: C07C217/60 ,  C07C255/59 ,  C07C323/32 ,  C07D317/58 ,  A61K31/277 ,  A61K31/145 ,  A61K31/138 ,  A61P25/22 ,  A61P25/24 ,  A61P27/00 ,  A61P29/00

Abstract: The present disclosure provides phenalkylamine compounds and their use in treating medical disorders, such as psychiatric diseases and disorders. Pharmaceutical compositions and methods of making various phenalkylamine compounds are provided.

公开(公告)号：WO2022006186A1

公开(公告)日：2022-01-06

申请号：PCT/US2021/039724

申请日：2021-06-29

Applicant: GILGAMESH PHARMACEUTICALS, INC.

Inventor： KRUEGEL, Andrew Carry

IPC: C07C217/60 ,  A61K31/138 ,  A61P25/22 ,  A61P25/24

Abstract: Phenalkylamines and methods of treating mood disorders with phenalkylamines. Also provided are pharmaceutical compositions that include phenalkylamines.