公开(公告)号：WO2007008715A2

公开(公告)日：2007-01-18

申请号：PCT/US2006026602

申请日：2006-07-07

申请人： INGENIOUS TARGETING LAB INC ,  ZHU LIQUN ,  WANG JIANNING ,  WENG WEI ,  SU RONG

发明人： ZHU LIQUN ,  WANG JIANNING ,  WENG WEI ,  SU RONG

IPC分类号： G06T7/20

CPC分类号： G06T7/20 ,  G06K9/00771 ,  G06K9/209

摘要： The present invention relates to a system for the 3-D monitoring and analysis of motion-related behavior of test subjects. The system comprises an actual camera, at least one virtual camera, a computer connected to the actual camera.and the computer is preferably installed with software capable of capturing the stereo images associated with the 3-D motion-related behavior of test subjects as well as processing these acquired image frames for the 3-D motion parameters of the subjects. The system of the invention comprises hardware components as well as software components. The hardware components preferably comprise a hardware setup or configuration, a hardware-based noise elimination component, an automatic calibration device component, and a lab animal container component. The software components preferably comprise a software-based noise elimination component, a basic calibration component, an extended calibration component, a linear epipolar structure derivation component, a non-linear epipolar structure derivation component, an image segmentation component, an image correspondence detection component, a 3-D motion tracking component, a software-based target identification and tagging component, a 3-D reconstruction component, and a data post-processing component. In a particularly preferred embodiment, the actual camera is a digital video camera, the virtual camera is the reflection of the actual camera in a planar reflective mirror. Therefore, the preferred system is a catadioptric stereo computer vision system.

摘要翻译： 本发明涉及一种用于三维监测和分析测试对象运动相关行为的系统。 该系统包括实际相机，至少一个虚拟相机，连接到实际相机的计算机，并且计算机优选地安装有能够捕获与测试对象的3D动作相关行为相关联的立体图像的软件 作为处理这些获取的图像帧用于受试者的3-D运动参数。 本发明的系统包括硬件组件以及软件组件。 硬件组件优选地包括硬件设置或配置，基于硬件的噪声消除组件，自动校准设备组件和实验室动物容器组件。 软件组件优选地包括基于软件的噪声消除组件，基本校准组件，扩展校准组件，线性对极结构导出组件，非线性对极结构导出组件，图像分割组件，图像对应检测组件， 3-D运动跟踪组件，基于软件的目标识别和标记组件，3-D重建组件和数据后处理组件。 在特别优选的实施例中，实际相机是数字摄像机，虚拟相机是实际相机在平面反射镜中的反射。 因此，优选的系统是反折射立体计算机视觉系统。

公开(公告)号：WO2008070537A3

公开(公告)日：2008-08-07

申请号：PCT/US2007086014

申请日：2007-11-30

申请人： INGENIOUS TARGETING LAB INC ,  WENG WEI ,  ZHU LIQUN

发明人： WENG WEI ,  ZHU LIQUN

IPC分类号： A43D11/00

CPC分类号： A43D1/025 ,  A43D3/021

摘要： This invention relates to a system and the methods of making custom footwear. A multi-level customization process is employed in the system of the invention. First, shoe last is customized according to the biometric features of the foot.Secondly, the components of the footwear are fine-tuned through a set of interactive measurements for the wearer' needs, while the appearance of the footwear is custom-designed according to the taste of the wearer. Major components of the custom footwear include a custom upper that best-fits the shape of wearer's foot, a multi-layered custom insole with its surface conforming to the plantar surface of the foot, and a custom sole that sandwiching a heel pad with custom height.

摘要翻译： 本发明涉及制造定制鞋类的系统和方法。 在本发明的系统中采用多级定制过程。 首先，鞋子根据脚的生物特征进行定制。其次，通过针对佩戴者需求的一组交互式测量，对鞋类的部件进行微调，而鞋类的外观根据 穿着者的味道。 定制鞋类的主要部件包括最适合穿戴者脚部形状的定制鞋面，多层定制鞋垫，其表面符合足底足底表面，以及定制鞋底，夹具具有定制高度的脚跟垫 。

公开(公告)号：WO2006044492A3

公开(公告)日：2006-08-31

申请号：PCT/US2005036742

申请日：2005-10-14

申请人： INGENIOUS TARGETING LAB INC ,  HE WEI ,  WENG WEI

发明人： HE WEI ,  WENG WEI

IPC分类号： C12N15/09 ,  C12N5/0735

CPC分类号： C12N5/0606 ,  A01K2217/075 ,  A01K2227/105 ,  C12N2501/155 ,  C12N2501/235 ,  C12N2502/13

摘要： The present invention provides novel methods for isolating rat embryo-derived cells and modifying the genome of the rat cells which typically comprise the steps of: constructing a DNA molecule in which desired sequence modifications are contained in a segment of DNA (a "targeting DNA); introducing the targeting DNA construct into the cell (e.g., by microinjection, electroporation, transfection, or calcium phosphate precipitation); and selecting cells in which the desired sequence modifications have been introduced into the genome via homologous recombination.

摘要翻译： 本发明提供了分离大鼠胚胎衍生细胞和修饰大鼠细胞基因组的新方法，其通常包括以下步骤：构建其中在DNA片段中包含期望的序列修饰的DNA分子（“靶向DNA”）， ;将靶向DNA构建体引入细胞（例如，通过显微注射，电穿孔，转染或磷酸钙沉淀）;以及通过同源重组选择其中所需的序列修饰已导入基因组的细胞。

公开(公告)号：WO2005118145A3

公开(公告)日：2006-10-12

申请号：PCT/US2005017829

申请日：2005-05-20

申请人： INGENIOUS TARGETING LAB INC ,  CHEN ELLEN ,  HE WEI ,  WENG WEI

发明人： CHEN ELLEN ,  HE WEI ,  WENG WEI

IPC分类号： B01L3/00 ,  B01L9/00

CPC分类号： B01L3/50853 ,  B01L3/5085 ,  B01L2300/0809 ,  B01L2300/0829

摘要： The invention provides for improved multi-well plates and platforms that comprise a plurality of wells having increased volume capacity and clustered in a standard multi-well plate format and dimensions, said multi-well plate format being compatible with auxiliary equipment currently used and designed for the particular multi-well plate format. More particularly, the invention provides improved multi-well plates comprising a base to improve wells having one or more said wells having rectangular configuration, better retention of working materials and tissue culture ingredients than observed in conventional round-shaped wells. A cover is provided for protecting the assembly and cell cultures.

摘要翻译： 本发明提供了改进的多孔板和平台，其包括具有增加的体积容量并且以标准多孔板格式和尺寸聚集的多个孔，所述多孔板格式与目前使用和设计的辅助设备兼容 特定的多孔板格式。 更具体地，本发明提供了改进的多孔板，其包括基底，以改进具有一个或多个所述孔的孔，所述孔具有矩形构型，比常规圆形孔中观察到的具有更好的保留作业材料和组织培养成分。 提供了一种保护组装和细胞培养的盖子。

公开(公告)号：WO2015013575A3

公开(公告)日：2015-04-02

申请号：PCT/US2014048122

申请日：2014-07-25

申请人： INGENIOUS TARGETING LAB INC

发明人： WENG WEI ,  CHEN YI MEI ,  HE WEI

IPC分类号： G09B7/00 ,  C12N15/87

CPC分类号： C12N15/8509 ,  A01K67/0275 ,  A01K67/0276 ,  A01K2217/075 ,  A01K2217/206 ,  A01K2227/105 ,  C12N2800/30

摘要： The present disclosure provides methods for generating embryonic stem cell lines with the integration of a site-specific recombinase deriving from recombinase mouse models. Utilizing methods of the present disclosure, targeting vectors including selection cassettes flanked by respective recognition sites may be removed in ES cells and thus resulting progeny o chimeras would have absence of the selection cassette.

摘要翻译： 本公开内容提供了用于产生源自重组酶小鼠模型的位点特异性重组酶的胚胎干细胞系的方法。 利用本公开内容的方法，可以在ES细胞中去除包含两侧各自的识别位点的选择盒的靶向载体，因此得到的后代或嵌合体将不存在选择盒。