公开(公告)号：WO2022261311A1

公开(公告)日：2022-12-15

申请号：PCT/US2022/032821

申请日：2022-06-09

Applicant: INSPIRE MEDICAL SYSTEMS, INC.

Inventor： THORP, Christopher ,  DIEKEN, David ,  NESBITT, Nicholas ,  RONDONI, John ,  MANNE-NICHOLAS, James ,  JONES, Ross Peter ,  SCHATZA, Mark ,  WARWICK, Christopher Nicholas ,  STONE, Jonathan Tudor ,  CANAS DE MATOS E OLIVEIRA RIBEIRO, Frederico

IPC: A61B5/113 ,  A61B5/00 ,  A61N1/36 ,  A61B5/08

Abstract: A device includes a sensor and a control portion. The sensor is securable to a patient to provide a sensor signal. The sensor is to sense changes in acceleration indicative of respiration of the patient. The control portion is to determine a midpoint of each respiratory phase of the patient based on the sensor signal.

公开(公告)号：WO2021252737A1

公开(公告)日：2021-12-16

申请号：PCT/US2021/036772

申请日：2021-06-10

Applicant: INSPIRE MEDICAL SYSTEMS, INC.

Inventor： DIEKEN, David ,  RONDONI, John ,  PIESSENS, Tim ,  GEWILLIG, Wim

IPC: A61N1/36 ,  H03K3/02 ,  A61N1/08 ,  A61N1/025 ,  A61N1/3603 ,  A61N1/36125 ,  H03K3/53

Abstract: An output signal driver includes a positive output node, a negative output node, a power supply input node, a power supply common node, a charging capacitor, a discharging capacitor, a current source, a current sink, a first switch, a second switch, and a controller. The charging capacitor is coupled to the power supply input node. The discharging capacitor is coupled to the negative output node. The current source is coupled between the power supply input node and the positive output node. The current sink is coupled between the positive output node and the power supply common node. The first switch is coupled in parallel with the current source. The second switch is coupled in parallel with the current sink. The controller is coupled to the current source, the current sink, the first switch, and the second switch to apply either complementary constant current pulses or complementary constant voltage pulses to the positive output node.

公开(公告)号：WO2021016558A1

公开(公告)日：2021-01-28

申请号：PCT/US2020/043493

申请日：2020-07-24

Applicant: INSPIRE MEDICAL SYSTEMS, INC.

Inventor： RONDONI, John ,  DIEKEN, David ,  THORP, Christopher

IPC: A61B5/0205 ,  A61B5/11 ,  A61B5/00 ,  A61B5/0402 ,  A61B5/08 ,  A61N1/36

Abstract: A device and/or method to determine a sleep-wake status, such as in association with sleep disordered breathing (SDB) care.

公开(公告)号：WO2021016562A1

公开(公告)日：2021-01-28

申请号：PCT/US2020/043500

申请日：2020-07-24

Applicant: INSPIRE MEDICAL SYSTEMS, INC.

Inventor： DIEKEN, David ,  RONDONI, John ,  NESBITT, Nicholas ,  THORP, Christopher ,  WAGNER, Darrell ,  VERZAL, Kevin

IPC: A61B5/113 ,  A61B5/11 ,  A61B5/08 ,  A61B5/00 ,  A61N1/36

Abstract: Methods and/or devices to determine patient respiration information are disclosed which comprise sensing acceleration.

公开(公告)号：WO2021016522A1

公开(公告)日：2021-01-28

申请号：PCT/US2020/043405

申请日：2020-07-24

Applicant: INSPIRE MEDICAL SYSTEMS, INC.

Inventor： VERZAL, Kevin ,  NESBITT, Nicholas ,  RONDONI, John ,  DIEKEN, David ,  THORP, Christopher

IPC: A61N1/36 ,  A61B5/00 ,  A61N1/05 ,  A61N1/372 ,  A61N1/365 ,  A61B5/0402 ,  A61B5/0476

Abstract: A system and/or method to control operation of an implantable medical device in response to sensed occurrence of a designated physical action intentionally performed by the patient.

公开(公告)号：WO2017197084A2

公开(公告)日：2017-11-16

申请号：PCT/US2017/032107

申请日：2017-05-11

Applicant: INSPIRE MEDICAL SYSTEMS, INC.

Inventor： VERZAL, Kevin ,  RONDONI, John ,  DIEKEN, David

IPC: A61N1/36 ,  A61N1/08

CPC classification number: A61N1/086 ,  A61N1/05 ,  A61N1/06

Abstract: An implantable medical device includes at least one conductive element and an associated attenuation arrangement to attenuate MRI energy.

Abstract translation: 可植入医疗装置包括至少一个导电元件和关联的衰减装置以衰减MRI能量。

公开(公告)号：WO2022020489A1

公开(公告)日：2022-01-27

申请号：PCT/US2021/042601

申请日：2021-07-21

Applicant: INSPIRE MEDICAL SYSTEMS, INC.

Inventor： THORP, Christopher ,  NESBITT, Nicholas ,  RONDONI, John ,  DIEKEN, David ,  VERZAL, Kevin ,  ORSER, Heather

IPC: A61B5/00 ,  A61B5/113 ,  A61B5/07 ,  A61N1/36 ,  A61B5/145

Abstract: Methods and/or devices to identify disease burden indication are disclosed. One type of disease comprises sleep disordered breathing and/or related parameters, which may be sensed via implantable sensors such as an acceleration sensor.

公开(公告)号：WO2021257366A1

公开(公告)日：2021-12-23

申请号：PCT/US2021/036760

申请日：2021-06-10

Applicant: INSPIRE MEDICAL SYSTEMS, INC.

Inventor： VERSTREKEN, Jan ,  PIESSENS, Tim ,  ORSER, Heather ,  DIEKEN, David ,  RONDONI, John ,  DENISON, Timothy

IPC: H03F3/181 ,  H03F3/38 ,  H03F3/45 ,  A61B5/30 ,  A61B5/304 ,  A61B5/305 ,  A61B5/307 ,  A61B5/308 ,  A61B5/31 ,  A61B5/311 ,  A61B5/313 ,  A61B5/00 ,  A61B5/7217 ,  A61N1/36125 ,  A61N1/362 ,  H03F2200/261 ,  H03F2200/264 ,  H03F2203/45138 ,  H03F2203/45526 ,  H03F2203/45534 ,  H03F2203/45591 ,  H03F3/45475 ,  H03F3/45928

Abstract: A device includes a sensor signal input node and a high-pass filter stage. The high-pass filter stage includes an operational amplifier and a feedback integrator. The operational amplifier includes an input node coupled to the sensor signal input node. The feedback integrator is coupled between an output node of the operational amplifier and the input node of the operational amplifier to set a high-pass pole frequency of the high-pass filter stage.

公开(公告)号：WO2021016536A1

公开(公告)日：2021-01-28

申请号：PCT/US2020/043442

申请日：2020-07-24

Applicant: INSPIRE MEDICAL SYSTEMS, INC.

Inventor： VERZAL, Kevin ,  DIEKEN, David ,  RONDONI, John

IPC: A61N1/36

Abstract: A system and/or method to control operation of an implantable medical device in response to sensed posture information.

公开(公告)号：WO2020102193A1

公开(公告)日：2020-05-22

申请号：PCT/US2019/060917

申请日：2019-11-12

Applicant: INSPIRE MEDICAL SYSTEMS, INC.

Inventor： DIEKEN, David ,  VERZAL, Kevin ,  RONDONI, John

IPC: A61N1/36 ,  A61B5/08 ,  A61B5/024 ,  A61B5/113 ,  A61B5/00 ,  A61N1/05 ,  A61N1/372

Abstract: A method includes delivering, via a first stimulation element and during a treatment period, stimulation to an upper airway patency-related nerve to cause contraction of upper airway patency-related muscles. The method also may include delivering upon detecting central sleep apnea behavior, via a second stimulation element and during a treatment period, stimulation to a central sleep apnea-related nerve. The method also may include delivering the stimulation to the upper airway patency-related nerve independently of a decisional process and trigger to deliver stimulation to the different central sleep apnea-related nerve.