公开(公告)号：WO2023059224A1

公开(公告)日：2023-04-13

申请号：PCT/RU2022/050228

申请日：2022-07-21

申请人： JOINT STOCK COMPANY "PHARMASYNTEZ"

发明人： KURKIN, Alexander Vital'evich ,  KAZYULKIN, Denis Nikolaevich ,  MANASOVA, Ekaterina Vladimirovna ,  LUKIANENKO, Evgenii Renol'dovich ,  BELOV, Grigorii Mihajlovich ,  IUSUPOV, Ildar Rustemovich ,  SHURYGIN, Mikhail Gennad'evich

IPC分类号： C07D209/10 ,  C07D235/02 ,  C07D307/58 ,  C07F9/12 ,  C07F9/24 ,  C07C255/36 ,  A61K31/341 ,  A61K31/404 ,  A61K31/661 ,  A61K31/664 ,  A61P31/12

摘要： The invention relates to new biologically active derivatives of substituted 2,3-dihydrofuran-3-ones, which can be used as antiviral agents with a broad spectrum of antiviral activity. The compound represented by Formula (I) is described: Formula (I). Also a method for treating viral disease, a method for preventing viral disease, pharmaceutical composition comprising compound according to claims 1-5 and pharmaceutically acceptable carrier and a method for obtaining of the compound of Formula (I) are described. The technical result of this invention is the development and production of new chemical compounds with high efficacy for the treatment of diseases caused by RNA viruses.