公开(公告)号：WO2016079219A1

公开(公告)日：2016-05-26

申请号：PCT/EP2015/077045

申请日：2015-11-19

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： VAN ROOSMALEN, Johannes Henricus Maria ,  SEMJONOW, Veronique ,  NIEUWENHUIS, Jeroen Hans

IPC: C07K14/435 ,  G01N33/569 ,  C07K16/18

CPC classification number: G01N33/6893 ,  C07K16/18 ,  C07K2317/34 ,  C07K2317/51 ,  C07K2317/515 ,  G01N33/56911 ,  G01N2333/4703 ,  G01N2800/26 ,  G01N2800/56 ,  G06F19/325 ,  G16H50/20

Abstract: The present invention relates to the means and methods for the detection of bacterial infections, methods discriminating between viral and bacterial infections, methods of stratifying patients for subsequent treatment and further diagnostic purposes and methods to monitor antibiotherapy. The present invention is based on the detection of specific epitopes of human neutrophil lipocalin (HNL) using specific binding agents.

Abstract translation: 本发明涉及用于检测细菌感染的方法和方法，区分病毒和细菌感染的方法，对患者进行后续治疗的分层方法以及进一步的诊断目的和监测抗生素治疗的方法。 本发明基于使用特异性结合剂检测人嗜中性粒细胞脂质运载蛋白（HNL）的特异性表位。

公开(公告)号：WO2016067153A1

公开(公告)日：2016-05-06

申请号：PCT/IB2015/057954

申请日：2015-10-16

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： JACOBS, Egbertus Reinier ,  PEETERS, Wouter Herman ,  WEEKAMP, Johannes Wilhelmus ,  VAN ROOSMALEN, Johannes Henricus Maria ,  BEZEMER, Rick ,  PAULUSSEN, Igor Wilhelmus Franciscus ,  VAN DER SAR, Toeno

IPC: A61B5/1455 ,  A61B5/00

CPC classification number: A61B5/6819 ,  A61B5/02416 ,  A61B5/14542 ,  A61B5/14552 ,  A61B5/6838 ,  A61M16/06

Abstract: When measuring SpO2 in a patient, a nasal oximeter is inserted into the patient's nose and comprises a source pad (14) and a detector pad (18) that are positioned at a predetermined location on either side of the nasal septum. The source pad and detector pad are biased toward each other to provide a clamping force on the nasal septum sufficient to permit SpO2 measurement without causing tissue necrosis. Clamping force is supplied by means of a spring type device, an expandable material, or the like.

Abstract translation: 当测量患者中的SpO2时，将鼻用血压计插入患者的鼻子中，并且包括位于鼻中隔两侧的预定位置处的源垫（14）和检测器垫（18）。 源极焊盘和检测器焊盘彼此偏置以在鼻中隔上提供足够的夹持力，以允许SpO2测量而不引起组织坏死。 夹紧力通过弹簧型装置，可膨胀材料等提供。