公开(公告)号：WO2019118046A1

公开(公告)日：2019-06-20

申请号：PCT/US2018/052829

申请日：2018-09-26

Applicant: L'OREAL ,  YALE UNIVERSITY

Inventor： GEORGE, Kelly, Marie ,  PAN, Zhi ,  MARROT, Laurent ,  WANG, Miao ,  BRASH, Douglas, Edgar ,  PREMI, Sanjay ,  GONCALVES, Leticia, C.P.

IPC: A61Q17/04

CPC classification number: A61K36/704 ,  A61K8/31 ,  A61K8/35 ,  A61K8/36 ,  A61K8/365 ,  A61K8/40 ,  A61K8/44 ,  A61K8/4926 ,  A61K8/498 ,  A61K8/9717 ,  A61K8/9789 ,  A61K31/01 ,  A61K31/015 ,  A61K31/12 ,  A61K31/19 ,  A61K31/192 ,  A61K31/353 ,  A61K31/366 ,  A61K31/44 ,  A61K36/04 ,  A61K36/287 ,  A61K36/355 ,  A61K36/48 ,  A61K36/539 ,  A61K47/12 ,  A61K47/24 ,  A61Q19/004

Abstract: A method for decreasing formation of one or more chemiexcitation-induced dark cyclobutane pyrimidine dimers (dCPDs) in a cell or DNA molecule in a subject, who has been exposed to UV radiation, is provided. The method comprises administering to the subject an effective amount of a dCPD quencher within 8 hours after the exposure. The dCPD quencher is selected from the group consisting of ellagic acid, Porphyra Umbilicalis Extract (including Porphyra Umbilicalis Extract (and) Sodium Lactate (and) Lecithin), mycosporine-like amino acids (MAAs) and synthetic analogues thereof, Scutellaria Baicalensis Root Extract, Chrysanthemum Morifolium Leaf Extract, ferulic acid, fused-ring cyanoacrylates, curcumin, epigallocatechin gallate, Scutellaria Baicalensis Root Extract (and) Acacia Catechu Wood Extract, sorbic acid, Polygonum Cuspidatum Root Extract, Acacia Catechu Extract, dipicolinic acid, squalene, Lonicera Japonica (Honeysuckle) Flower Extract, beta-carotene and combinations thereof. The dCPD quencher may be administered to the subject in the absence of UV radiation.

公开(公告)号：WO2021202493A1

公开(公告)日：2021-10-07

申请号：PCT/US2021/024836

申请日：2021-03-30

Applicant: L'OREAL ,  LE CLAIRE, Laurianne ,  WANG, Miao ,  COTTARD, Jerome

Inventor： LE CLAIRE, Laurianne ,  WANG, Miao ,  COTTARD, Jerome

IPC: A61K8/14 ,  A61K8/34 ,  A61K8/35 ,  A61K8/42 ,  A61K8/68 ,  A61K8/85 ,  A61K8/90 ,  A61Q5/02 ,  A61Q19/00 ,  A61Q19/08 ,  A61K8/342 ,  A61Q19/004 ,  A61Q19/007

Abstract: The ceramide composition includes capsules dispersed in the ceramide composition, the capsules comprising a shell and a core. The shell includes a polycaprolactone, a block copolymer, and a surfactant. The core includes ceramide NP, hydroxypalmitoyl sphinganine, 2-oleamido-1,3-octadecanediol, and a hydrophobic solvent. The core has a weight ratio of the ceramide NP of (i) and the hydroxypalmitoyl sphinganine of (ii) to the 2-oleamido-1,3-octadecanediol of (iii) is from 1:2.5 to 1:5. Additionally, the ceramide composition includes hydroxyacetophenone and hydrophilic solvent.

公开(公告)号：WO2017116944A1

公开(公告)日：2017-07-06

申请号：PCT/US2016/068205

申请日：2016-12-22

Applicant: L'OREAL ,  MANNING, Lauren, E. ,  WANG, Miao ,  GALDI, Angelike, A. ,  CHIOU, Catherine

Inventor： MANNING, Lauren, E. ,  WANG, Miao ,  GALDI, Angelike, A. ,  CHIOU, Catherine

IPC: A61K8/25 ,  A61Q19/08

CPC classification number: A61K8/25 ,  A61K8/26 ,  A61K8/345 ,  A61K8/73 ,  A61K8/8147 ,  A61K8/8152 ,  A61K8/8164 ,  A61K8/8176 ,  A61K8/86 ,  A61K8/87 ,  A61K8/891 ,  A61K8/892 ,  A61K8/895 ,  A61K2800/48 ,  A61K2800/548 ,  A61K2800/596 ,  A61Q19/00 ,  A61Q19/007 ,  A61Q19/08

Abstract: The present disclosure relates to cosmetic compositions that provide immediate skin-tightening and long-lasting improvements to the skin for the treatment of, for example, eye bags, facial wrinkles, and other age-related skin imperfections. The compositions comprise: (a) a first film former sodium silicate; (b) at least one second film former; (c) at least one polyvalent silicate thickener; (d) at least one anionic associative polymeric thickener; (e) at least one plasticizer; and (f) optionally at least one cosmetic powder.

Abstract translation: 本公开涉及化妆品组合物，其为皮肤提供即时紧肤和持久改善，用于治疗例如眼袋，面部皱纹和其他与年龄有关的皮肤瑕疵 。 该组合物包含：（a）第一成膜剂硅酸钠; （b）至少一个第二成膜剂; （c）至少一种多价硅酸盐增稠剂; （d）至少一种阴离子缔合聚合物增稠剂; （e）至少一种增塑剂; 和（f）任选地至少一种化妆粉。

公开(公告)号：WO2017102728A1

公开(公告)日：2017-06-22

申请号：PCT/EP2016/080799

申请日：2016-12-13

Applicant: L'OREAL

Inventor： COGNET, Marie ,  MATHONNEAU, Estelle ,  WANG, Miao ,  MORVAN, Christelle ,  DURAND, Morgan

IPC: A61K8/36 ,  A61K8/44 ,  A61K8/46 ,  A61Q5/00

CPC classification number: A61Q5/006 ,  A61K8/361 ,  A61K8/44 ,  A61K8/463 ,  A61K8/466

Abstract: The invention relates to a cosmetic composition which comprises: (i) one or more anionic surfactants, (ii) at least 3.5% by weight of one or more fatty acids, relative to the total weight of the composition, and (iii) one or more antidandruff agents, the anionic surfactant(s)/fatty acid(s) weight ratio being from 0.5 to 3.5. The invention also relates to the use of said composition for washing and conditioning the hair.

Abstract translation: 本发明涉及一种化妆品组合物，其包含：（i）一种或多种阴离子表面活性剂，（ii）相对于所述组合物的总重量的至少3.5重量％的一种或多种脂肪酸 （iii）一种或多种去头屑剂，所述阴离子表面活性剂/脂肪酸的重量比为0.5-3.5。 本发明还涉及所述组合物用于洗涤和调理头发的用途。

公开(公告)号：WO2017116948A1

公开(公告)日：2017-07-06

申请号：PCT/US2016/068213

申请日：2016-12-22

Applicant: L'OREAL ,  MANNING, Lauren, E. ,  WANG, Miao ,  GALDI, Angelike, A. ,  CHIOU, Catherine

Inventor： MANNING, Lauren, E. ,  WANG, Miao ,  GALDI, Angelike, A. ,  CHIOU, Catherine

IPC: A61K8/02 ,  A61K8/73 ,  A61Q19/08 ,  C12P19/10

CPC classification number: A61K8/73 ,  A61K8/0241 ,  A61K8/25 ,  A61K8/26 ,  A61K8/8152 ,  A61K8/8164 ,  A61K2800/48 ,  A61K2800/548 ,  A61K2800/594 ,  A61Q19/00 ,  A61Q19/007 ,  A61Q19/08

Abstract: The present disclosure relates to cosmetic compositions that provide immediate skin-tightening and long-lasting improvements to the skin for the treatment of, for example, eye bags, facial wrinkles, and other age-related skin imperfections. The compositions comprise: (a) at least one film former; (b) at least one polyvalent silicate thickener; (c) at least one anionic associative polymeric thickener; (d) at least one plasticizer; and (e) optionally, at least one cosmetic powder.

Abstract translation: 本公开涉及化妆品组合物，其为皮肤提供即时紧肤和持久改善，用于治疗例如眼袋，面部皱纹和其他与年龄有关的皮肤瑕疵 。 该组合物包含：（a）至少一种成膜剂; （b）至少一种多价硅酸盐增稠剂; （c）至少一种阴离子缔合聚合物增稠剂; （d）至少一种增塑剂; 和（e）任选的至少一种化妆粉。

公开(公告)号：WO2016087948A3

公开(公告)日：2016-06-09

申请号：PCT/IB2015/002519

申请日：2015-12-04

Applicant: L'OREAL

Inventor： HALPERN CHIRCH, Susan ,  LI, Chunhua ,  WANG, Miao

IPC: A61Q17/00 ,  A61K8/11 ,  A61K8/35 ,  A61K8/40 ,  A61K8/49

Abstract: The instant disclosure relates to photosensitive capsules (sometimes referred to as "smart capsules") and sunscreen compositions comprising the capsules that automatically adjust the Sun Protection Factor ("SPF") of the sunscreen composition during use to provide protection against ultraviolet ("UV") light, as needed, based on actual exposure to UV light. The photosensitive capsules comprise: (i) a polymeric photosensitive degradable shell; and (ii) one or more UV filters encapsulated by the photosensitive degradable shell, wherein the one or more UV filters is released from the photosensitive degradable shell upon exposure to UV light.

Abstract translation: 本发明涉及包含胶囊的光敏胶囊（有时称为“智能胶囊”）和防晒组合物，所述胶囊自动调节防晒组合物的防晒因子（“SPF”） 用于根据需要基于实际暴露于UV光提供防紫外线（“UV”）光的保护。 光敏胶囊包含：（i）聚合物光敏可降解壳; 和（ii）由所述光敏可降解外壳包封的一个或多个UV滤光片，其中所述一个或多个UV滤光片在暴露于UV光时从所述光敏可降解壳释放。

公开(公告)号：WO2015086608A1

公开(公告)日：2015-06-18

申请号：PCT/EP2014/077068

申请日：2014-12-09

Applicant: L'OREAL

Inventor： RIZK, Kirolos ,  WANG, Miao

IPC: A61K8/39 ,  A61K8/41 ,  A61K8/44 ,  A61K8/46 ,  A61Q5/02 ,  A61K8/60 ,  A61K8/81 ,  A61K8/86 ,  A61K8/04 ,  A61Q19/10

CPC classification number: A61K8/042 ,  A61K8/39 ,  A61K8/416 ,  A61K8/44 ,  A61K8/442 ,  A61K8/463 ,  A61K8/466 ,  A61K8/602 ,  A61K8/817 ,  A61K8/86 ,  A61K2800/596 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q19/10

Abstract: The present invention is directed to a cleansing composition comprising : (a) at least one nonionic surfactant; (b) at least one amphoteric surfactant; (c) at least one component selected from (i) a nonionic thickener or (ii) (1) a cationic agent combined with (ii) (2) an anionic surfactant, or a mixture of nonionic thickener plus cationic agent and/or anionic surfactant; and (d) water.

Abstract translation: 本发明涉及一种清洁组合物，其包含：（a）至少一种非离子表面活性剂; （b）至少一种两性表面活性剂; （c）至少一种选自（i）非离子增稠剂或（ii）（1）阳离子剂与（ii）（2）阴离子表面活性剂或非离子增稠剂加阳离子剂和/或阴离子的混合物 表面活性剂; 和（d）水。