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1.NOVEL N-ACYL-ARYLSULFONAMIDE DERIVATIVES AS AMINOACYL-TRNA SYNTHETASE INHIBITORS 审中-公开
标题翻译: 新型N-亚氨基磺酰胺衍生物作为氨基酰基-TNA合成酶抑制剂公开(公告)号:WO2016129983A1
公开(公告)日:2016-08-18
申请号:PCT/LV2016/000001
申请日:2016-02-11
发明人: JIRGENSONS, Aigars , LOZA, Einars , CHARLTON, Michael , FINN, Paul William , RIBAS DE POUPLANA, Lluis , SAINT-LEGER, Adelaide
IPC分类号: C07D213/71 , C07D311/20 , C07D215/36 , C07D217/22 , C07C311/00 , C07D239/42 , C07D239/47 , C07D239/48 , C07D251/22 , C07D487/04 , A61K31/4402 , A61K31/47 , A61K31/505 , A61K31/18 , A61P31/00
CPC分类号: C07C311/51 , C07C2601/02 , C07D213/71 , C07D215/06 , C07D215/36 , C07D217/04 , C07D217/22 , C07D217/26 , C07D239/42 , C07D239/47 , C07D239/48 , C07D251/22 , C07D311/04 , C07D311/20 , C07D487/04
摘要: The present invention relates to novel N-acyl-diarysulfonamides acting as inhibitors of bacterial aminoacyl-tRNA synthetase. These can be used as medicines or as constituent of medicines for the treatment of bacterial infections.
摘要翻译: 本发明涉及作为细菌氨酰-tRNA合成酶抑制剂的新型N-酰基 - 二芳基磺酰胺。 这些可用作药物或用作治疗细菌感染的药物的组成部分。