公开(公告)号：WO2008014547A1

公开(公告)日：2008-02-07

申请号：PCT/AU2007/001066

申请日：2007-07-31

Applicant: LE COUTEUR, David ,  COGGER, Victoria

Inventor： LE COUTEUR, David ,  COGGER, Victoria

IPC: C12N5/06 ,  C12N15/06 ,  C12N15/65 ,  C12N5/16

CPC classification number: G01N33/5064 ,  G01N33/5067 ,  G01N2800/52

Abstract: The present invention relates generally to a population of cells genetically modified to express a detectable marker of fenestration and uses thereof. The cells of the present invention are useful in a wide variety of applications, in particular in the context of in vitro based screening systems for testing the effectiveness and/or toxicity of potential therapeutic or prophylactic treatment regimes.

Abstract translation: 本发明一般涉及经遗传修饰以表达可检测的开窗标志物的细胞群及其用途。 本发明的细胞可用于各种各样的应用，特别是在用于测试潜在的治疗或预防治疗方案的有效性和/或毒性的基于体外的筛选系统的上下文中。