Abstract:
An analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample (e.g., a whole blood sample) includes a first and second capillary sample-receiving chambers and first and second stop junctions that are disposed between the first and second capillary sample-receiving chambers. The first stop junction defines a discontinuity boundary of the first capillary sample-receiving chamber and the second stop junction defines a discontinuity boundary of the second capillary sample-receiving chamber. In addition, the first stop junction and the second stop junction are disposed such that bodily fluid sample flow between the first capillary sample-receiving chamber and the second capillary sample-receiving chamber during use of the analytical test strip is prevented.
Abstract:
An analytical test strip for the determination of an analyte (such as glucose) in, or a characteristic of, a bodily fluid sample includes an electrically-insulating base layer, a first patterned spacer layer disposed on the electrically-insulating base layer, a second patterned spacer layer disposed on the first patterned spacer layer; and a top hydrophilic layer disposed on the second patterned spacer layer. In addition, the electrically-insulating base layer, the first and second patterned spacer layers and the top hydrophilic layer define a tiered capillary chamber(s) that has a first tiered capillary chamber portion defined in the first patterned spacer layer and a second tiered capillary chamber portion defined in the second patterned spacer layer. Moreover, the first tiered capillary chamber portion and the second tiered capillary chamber portion are in direct fluidic communication with one another.
Abstract:
An analytical test strip ("ATS") for use with a hand-held test meter in the determination of an analyte in a bodily fluid sample includes an electrically insulting substrate (102), a first patterned conductor layer (104) disposed on the electrically insulating substrate and having a working electrode (128a, 128b) and a reference electrode (130). The ATS also includes an enzymatic reagent layer (106) disposed on the working electrode, a first patterned spacer layer (108) disposed over the first patterned conductor layer and defining both a first sample-receiving channel (112) and an analyte determination sample chamber (114) within the ATS, and a second patterned spacer layer (110) disposed over the first patterned spacer layer and defining at least a second sample-receiving channel (120). The ATS further includes a bodily fluid phase-shift sample chamber (116) in fluidic communication with the second sample-receiving channel. The first sample-receiving channel (112) and analyte determination sample chamber (114) are isolated from the second sample-receiving channel (120) and bodily fluid phase-shift sample chamber (116).
Abstract:
Various embodiments for a method that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic, typically hematocrit, of the sample containing the analyte and deriving from this characteristic a parameter relating to the biosensor to attain accurate glucose concentration.
Abstract:
Glucose concentration determination with a biosensor by determining at least one physical characteristic of the blood sample, typically hematocrit percentage, and deriving one of a batch slope, a sampling time, or combinations thereof to attain glucose concentration.
Abstract:
Various embodiments for a method that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic signal representative of the sample containing the analyte and selecting an analyte measurement sampling time based on measured temperature, physical characteristic and estimated analyte values.
Abstract:
An analytical test strip for the determination of an analyte (such as glucose and/or hematocrit) in a bodily fluid sample (such as a whole blood sample) includes a first capillary sample-receiving chamber, a second capillary sample-receiving chamber, and a physical barrier island disposed between the first and second capillary sample-receiving chambers. Moreover, the physical island barrier is disposed such that bodily fluid sample flow between the first capillary sample-receiving chamber and the second capillary sample-receiving chamber is prevented during use of the analytical test strip.
Abstract:
An electrochemical-based analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample (for example, a whole blood sample) and/or a characteristic of the bodily fluid sample (for example, hematocrit) includes a first sample-receiving chamber with first and second sample-application openings, and first and second electrodes. The first and second electrodes are disposed in the first sample-receiving chamber between the first and second sample-application openings. The electrochemical-based analytical test strip also includes a second sample-receiving chamber and a plurality of electrodes disposed in the second sample-receiving chamber. In addition, the second sample-receiving chamber intersects the first sample-receiving chamber between the first and second electrodes, thereby defining a chamber intersection.
Abstract:
Various embodiments that allow for determination of hematocrit by a time differential between the input and output signals such that a glucose measurement for a blood sample can be corrected by the measured hematocrit of the blood sample.
Abstract:
Two techniques of determining hematocrit using impedance and phase angle to determine hematocrit are shown and described for correcting an analyte concentration.