公开(公告)号：WO2017034942A1

公开(公告)日：2017-03-02

申请号：PCT/US2016/047692

申请日：2016-08-19

Applicant: MANUS BIOSYNTHESIS, INC.

Inventor： PIRIE, Christopher ,  LI, Liwei ,  MAK, Huey-ming ,  TIBREWALA, Srishti ,  DONALD, Jason ,  KUMARAN, Ajikumar, Parayil

IPC: C12N9/00 ,  C12N5/00 ,  C12N1/21 ,  C12N5/04

CPC classification number: C12P5/007 ,  C12N9/00 ,  C12N15/52 ,  C12P19/56

Abstract: The present invention relates to the production of chemical species in bacterial host cells. Particularly, the present invention provides for the production of chemical species in Escherichia coli (E. coli) host cells that functionally express engineered P450 enzymes.

Abstract translation: 本发明涉及细菌宿主细胞中化学物质的生产。 特别地，本发明提供了功能性表达工程化的P450酶的大肠杆菌（E.coli）宿主细胞中的化学物质的生产。