公开(公告)号：WO2010077301A1

公开(公告)日：2010-07-08

申请号：PCT/US2009/006536

申请日：2009-12-14

Applicant: MATERIALS MODIFICATION, INC. ,  MONTES, Joseph, G. ,  RANGAN, Krishnaswamy, K. ,  RADHAKRISHNAN, Ramachandran ,  SUDARSHAN, Tirumalai, S.

Inventor： MONTES, Joseph, G. ,  RANGAN, Krishnaswamy, K. ,  RADHAKRISHNAN, Ramachandran ,  SUDARSHAN, Tirumalai, S.

IPC: A61L15/16

CPC classification number: A61K31/765 ,  A61K9/0007 ,  A61K9/0019 ,  A61K9/0024 ,  A61K31/74 ,  A61K33/40 ,  A61K2300/00 ,  A61L15/18 ,  A61L15/425 ,  A61L26/0004 ,  A61L26/0085 ,  A61L2400/04

Abstract: A composition for in situ formation and/or expansion of a polymer- based hemostatic agent to control bleeding includes a suitable amount of a polymer or polymer-forming component, hydrogen peroxide or chemical(s) capable of forming hydrogen peroxide, or a combination of both, and a decomposing agent for hydrogen peroxide. The decomposing agent includes an endogenously or exogenously supplied catalyst (other than catalase), or both, and/or the polymer or polymer-forming component.

Abstract translation: 用于原位形成和/或膨胀聚合物基止血剂以控制渗血的组合物包括适量的聚合物或聚合物形成组分，过氧化氢或能够形成过氧化氢的化学物质，或组合 两者和一种过氧化氢分解剂。 分解剂包括内生或外源供应的催化剂（除了过氧化氢酶）或两者，和/或聚合物或聚合物形成组分。

公开(公告)号：WO2014152481A1

公开(公告)日：2014-09-25

申请号：PCT/US2014/027388

申请日：2014-03-14

Applicant: MATERIALS MODIFICATION INC. ,  KAUSIK, Mukhopadhyay ,  RANGAN, Krishnaswamy, K. ,  SUDARSHAN, Tirumalai, S.

Inventor： KAUSIK, Mukhopadhyay ,  RANGAN, Krishnaswamy, K. ,  SUDARSHAN, Tirumalai, S.

IPC: A61L15/18

CPC classification number: A61L15/18 ,  A61L15/44 ,  A61L15/46 ,  A61L2300/402 ,  A61L2300/404

Abstract: Clay composite sheets, mats, films or membranes without polymers. Methods of preparing clay composite sheets, mats, films or membranes without using polymers in the method. Methods of using clay composite sheets, mats, films or membranes prepared without using polymers. Antimicrobial dressing having organo-modified clay product. Transdermal delivery of drugs using organo- modified clay product and methods.

Abstract translation: 粘土复合片，垫，膜或无聚合物的膜。 在该方法中不使用聚合物制备粘土复合片，垫，膜或膜的方法。 使用不使用聚合物制备的粘土复合片材，垫，膜或膜的方法。 具有有机改性粘土制品的抗菌敷料。 使用有机改性粘土产品和方法透皮输送药物。

公开(公告)号：WO2014144523A2

公开(公告)日：2014-09-18

申请号：PCT/US2014/028973

申请日：2014-03-14

Applicant: MATERIALS MODIFICATION INC.

Inventor： HARIPRAKASHA, Humcha, Krishnamurthy ,  RANGAN, Krishnaswamy, K. ,  SUDARSHAN, Tirumalai, S.

IPC: H04L29/06

CPC classification number: H01M10/0567 ,  C07D233/58 ,  C07D233/61 ,  C07F9/11 ,  C07F9/5407 ,  D06M13/282 ,  D06M13/325 ,  D06M13/35 ,  D06M13/352 ,  D06M13/473 ,  D06M2200/30 ,  H01M10/0525 ,  H01M10/0566 ,  H01M10/4235 ,  H01M12/02 ,  H01M12/08 ,  H01M2300/0025 ,  Y02P20/542 ,  Y10T442/2664 ,  Y10T442/268

Abstract: Disclosure of fmictionalized ionic liquids. 'Use of disclosed ionic liquids as solvent for carbon dioxide. Use of disclosed ionic liquids as flame retardaat. Use of disclosed ionic liquids for coating fabric to obtain flame reiardani fabric.

Abstract translation: fmictionalized离子液体的公开。 “使用公开的离子液体作为二氧化碳的溶剂。 使用公开的离子液体作为阻燃剂。 使用所公开的离子液体涂布织物以获得火焰纹理织物。

公开(公告)号：WO2013025685A1

公开(公告)日：2013-02-21

申请号：PCT/US2012/050716

申请日：2012-08-14

Applicant: MATERIALS MODIFICATION, INC. ,  MUKHOPADHYAY, Kausik ,  RANGAN, Krishnaswamy, K. ,  SUDARSHAN, Tirumalai, S.

Inventor： MUKHOPADHYAY, Kausik ,  RANGAN, Krishnaswamy, K. ,  SUDARSHAN, Tirumalai, S.

IPC: A61L15/42

CPC classification number: A61K31/74 ,  A61K31/80 ,  A61L15/425 ,  A61L24/001 ,  A61L24/0015 ,  A61L24/0089 ,  A61L26/0009 ,  A61L26/0085 ,  A61L2300/11 ,  A61L2300/404 ,  A61L2400/04 ,  A61L2400/06 ,  C08L83/04 ,  C08L71/02

Abstract: Two siloxane-based mixtures combine to form a soft or semi-solid matrix for forming an artificial blockage to control bleeding, particularly moderate to severe bleeding. The first component includes a homogeneous mixture or solution that includes a polymeric matrix, a surfactant, filler(s) and metal compound(s). The second component includes a homogeneous mixture or solution that includes a polymer(s), a filler(s), a surfactant, and hydrogen peroxide. The combination of the two components is carried out with adequate mixing using mechanical and micro- kinetic mixing mechanisms and can be performed in a field-ready delivery device.

Abstract translation: 两种硅氧烷基混合物结合形成软或半固体基质，用于形成人造阻塞以控制出血，特别是中度至重度出血。 第一组分包括均匀的混合物或溶液，其包括聚合物基质，表面活性剂，填料和金属化合物。 第二组分包括均匀的混合物或溶液，其包括聚合物，填料，表面活性剂和过氧化氢。 两种组分的组合在使用机械和微动力混合机理的充分混合下进行，并且可以在现场准备的输送装置中进行。