公开(公告)号：WO2017019642A2

公开(公告)日：2017-02-02

申请号：PCT/US2016/043950

申请日：2016-07-25

申请人： MEDTRONIC, INC. ,  LURA, David, B. ,  HOBOT, Christopher, M. ,  GERBER, Martin, T. ,  MEYER, Thomas, E.

发明人： LURA, David, B. ,  HOBOT, Christopher, M. ,  GERBER, Martin, T. ,  MEYER, Thomas, E.

IPC分类号： A61M1/16

CPC分类号： A61M1/169 ,  A61M1/1656 ,  A61M1/1666 ,  A61M1/1668 ,  A61M1/267 ,  A61M39/12 ,  A61M39/223 ,  A61M2205/3337 ,  A61M2205/6018 ,  A61M2209/08 ,  A61M2209/082

摘要： The invention relates to fluid flow paths and fluid connectors for use with detachable containers that can be seated in an infusate caddy for use in a dialysis machine. The detachable containers can contain infusates or other solutes or materials such as disinfectants or cleaners, and can be conveniently seated in the infusate caddy. The detachable containers can be removed from the infusate caddy for restocking, cleaning, or resupply, as needed. The infusate caddy can be positioned or seated in a receiving compartment of a dialysis machine, and can also be removed, as needed. The fluid path and fluid connectors of the present invention provide the required fluid fittings, valve arrangements, pumps, and paddle assemblies for using the infusate caddy.

摘要翻译： 本发明涉及用于与可拆卸容器一起使用的流体流动路径和流体连接器，该可分离容器可以坐落在用于透析机中的输液管道中。 可拆卸的容器可以容纳输入物或其他溶质或材料，例如消毒剂或清洁剂，并且可以方便地安置在输液罐中。 根据需要，可拆卸的容器可从输液罐中取出，用于补充，清洗或补给。 输液罐可以定位或坐在透析机的接收室中，并且还可以根据需要移除。 本发明的流体路径和流体连接器提供了所需的流体配件，阀门装置，泵和用于使用输送槽的桨组件。

公开(公告)号：WO2015199768A1

公开(公告)日：2015-12-30

申请号：PCT/US2015/020047

申请日：2015-03-11

申请人： MEDTRONIC, INC. ,  GERBER, Martin, T. ,  HOBOT, Christopher, M.

发明人： GERBER, Martin, T. ,  HOBOT, Christopher, M.

IPC分类号： A61M1/16 ,  A61M1/34

CPC分类号： B01J20/28052 ,  A61M1/1696 ,  B01J20/0211 ,  B01J20/06 ,  B01J20/20 ,  B01J20/22 ,  B01J2220/66

摘要： A stacked sorbent assembly for use in sorbent dialysis. The stacked sorbent assembly contains two or more interchangeable sorbent pouches that allow for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouches. Any of the pouches in the sorbent cartridge can be reused and/or recharged.

摘要翻译： 用于吸附剂透析的堆叠吸附剂组件。 堆叠的吸附剂组件包含两个或更多个可互换的吸附剂袋，其允许流体自由地进入和穿过吸附剂材料，同时将吸附剂材料保持在吸附剂袋内。 吸附剂盒中的任何袋可以重复使用和/或再充电。

公开(公告)号：WO2009129510A4

公开(公告)日：2009-10-22

申请号：PCT/US2009/041042

申请日：2009-04-17

申请人： WARSAW ORTHOPEDIC, INC. ,  MEDTRONIC, INC. ,  ZANELLA, John, Myers ,  KING, Vanja, Margareta ,  HOBOT, Christopher, M. ,  BIGGS, Danielle ,  COX, S., Mark ,  SHAW, Katara

发明人： ZANELLA, John, Myers ,  KING, Vanja, Margareta ,  HOBOT, Christopher, M. ,  BIGGS, Danielle ,  COX, S., Mark ,  SHAW, Katara

IPC分类号： A61K9/00 ,  A61K31/255 ,  A61P29/00

摘要： Effective treatments of pain and/or inflammation for extended periods of time are provided. Through the administration of an effective amount of sulindac or a pharmaceutically acceptable salt thereof at or near a target site, one can relieve pain and/or inflammation caused by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain, as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least three days, at least twenty-five days. In some embodiments, the relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.

公开(公告)号：WO2005058414A1

公开(公告)日：2005-06-30

申请号：PCT/US2004/041212

申请日：2004-12-09

申请人： MEDTRONIC, INC. ,  COBIAN, Kenneth, E. ,  RIES, Richard, D. ,  DONOVAN, Maura, G. ,  SPARER, Randall, V. ,  SKIME, Robert, M. ,  SINGHAL, Ruchika ,  LENT, Mark, S. ,  HOOPER, William, J. ,  HOBOT, Christopher, M. ,  HERUTH, Kenneth, T.

发明人： COBIAN, Kenneth, E. ,  RIES, Richard, D. ,  DONOVAN, Maura, G. ,  SPARER, Randall, V. ,  SKIME, Robert, M. ,  SINGHAL, Ruchika ,  LENT, Mark, S. ,  HOOPER, William, J. ,  HOBOT, Christopher, M. ,  HERUTH, Kenneth, T.

IPC分类号： A61N1/375

CPC分类号： A61N1/375 ,  A61L27/34 ,  A61L27/54 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/406 ,  A61N1/3605

摘要： An anti-infective covering for an implantable medical device is described. The covering may be a polymeric boot that comprises an anti-infective agent in an amount effective to prevent an infection when implanted in a pocket of a patient. The boot is configured to snuggly engage at least a portion of the implantable medical device. The boot may contain a side hole that allows a housing of the implantable medical device to serve as a return electrode. The boot may be placed about the implantable medical device to render the device anti-infective.

摘要翻译： 描述了用于可植入医疗装置的抗感染覆盖物。 覆盖物可以是聚合物护套，其包含有效防止植入患者口袋时感染的抗感染剂。 靴子被配置成紧密接合可植入医疗装置的至少一部分。 靴子可以包含允许可植入医疗装置的壳体用作返回电极的侧孔。 引导可以围绕可植入医疗装置放置以使装置抗感染。

公开(公告)号：WO2004026933A1

公开(公告)日：2004-04-01

申请号：PCT/US2003/029151

申请日：2003-09-16

申请人： MEDTRONIC, INC.

发明人： BENZ, Michael, E. ,  HOBOT, Christopher, M. ,  BONNEMA, Kelvin ,  SPARER, Randall, V.

IPC分类号： C08G18/10

CPC分类号： C08G77/60 ,  C08G18/10 ,  C08G18/3893 ,  C08G18/6469 ,  C08G77/00 ,  C08G18/3206

摘要： Polymers that include silane-containing groups in soft segments, and optionally urethane groups, as well as medical devices and methods for making such compounds.

摘要翻译： 在软链段中包含含硅烷的基团和任选的氨基甲酸酯基团的聚合物，以及用于制备这些化合物的医疗装置和方法。

公开(公告)号：WO2004014447A1

公开(公告)日：2004-02-19

申请号：PCT/US2003/025510

申请日：2003-08-13

申请人： MEDTRONIC, INC.

发明人： LYU, SuPing ,  SPARER, Randall, V. ,  HOBOT, Christopher, M. ,  DANG, Kiem

IPC分类号： A61L27/16

CPC分类号： A61L27/26 ,  A61K9/0024 ,  A61L27/16 ,  A61L27/34 ,  A61L27/54 ,  A61L29/16 ,  A61L31/048 ,  A61L31/16 ,  A61L2300/602 ,  C08L33/10

摘要： The present invention provides active agent delivery systems for use in medical devices, wherein the active agent delivery systems include an active agent and a miscible polymer blend that includes a polyethylene-co-(meth)acrylate) and a second polymer not including polyethylene vinyl acetate).

摘要翻译： 本发明提供用于医疗装置的活性剂递送系统，其中活性剂递送系统包括活性剂和包含聚乙烯 - 共 - （甲基）丙烯酸酯的可混溶的聚合物共混物）和不包括聚乙烯乙酸乙烯酯的第二聚合物 ）。

公开(公告)号：WO2003053235A3

公开(公告)日：2003-07-03

申请号：PCT/US2002/039722

申请日：2002-12-12

申请人： MEDTRONIC INC.

发明人： HOBOT, Christopher, M. ,  SPEAR, Stanton, C. ,  KELLEY, James, F. ,  BAUNSCHWEIG, Jennifer, L. ,  DANG, Kiem ,  GARDESKI, Kenneth, C.

IPC分类号： A61L29/18

摘要： A guide catheter has properties that promote enhanced visibility of the guide catheter using fluoroscopic or ultrasonic imaging techniques. The tip of the guide catheter may incorporate a material that is both fluoro and echo visible. The first material also may be provided in various amounts along the length of the guide catheter. In addition, the guide catheter may incorporate a reinforcing braid that includes one or more strands of a second material that is radio-opaque. As a result, the result guide catheter achieves improved radio-opacity and echogenicity.

公开(公告)号：WO2003042273A1

公开(公告)日：2003-05-22

申请号：PCT/US2002/036332

申请日：2002-11-13

申请人： MEDTRONIC, INC.

发明人： DIDOMENICO, Edward ,  HOBOT, Christopher, M. ,  BENZ, Michael, E. ,  WAGENER, Kenneth, B. ,  SCHWENDEMAN, John, E.

IPC分类号： C08G18/62

CPC分类号： C08G18/6204 ,  A61L27/18 ,  C08F236/20 ,  C08L75/00 ,  C08L101/02

摘要： Compounds that include diorgano groups having quaternary carbons and optionally urethane groups, urea groups, or combinations thereof (i.e., polyyurethanes, polyureas, or polyurethane-ureas), as well as materials and methods for making such compounds.

摘要翻译： 包括具有季碳和任选的氨基甲酸酯基团的二有机基团，脲基团或其组合（即聚氨酯，聚脲或聚氨酯 - 脲）的化合物，以及用于制备这些化合物的材料和方法。

公开(公告)号：WO2016191040A1

公开(公告)日：2016-12-01

申请号：PCT/US2016/030312

申请日：2016-04-29

申请人： MEDTRONIC, INC.

发明人： MENON, Kanjimpuredathil, Muralikrishna ,  JEYACHANDRAN, Ramkumar ,  DUTTA, Sukalyan ,  HOBOT, Christopher, M. ,  LURA, David, B.

IPC分类号： A61M1/16 ,  B01J20/06 ,  B01J20/34 ,  B01J20/02

CPC分类号： A61M1/1696 ,  A61M2230/207 ,  A61M2230/65 ,  B01J20/0211 ,  B01J20/0292 ,  B01J20/06 ,  B01J20/28052 ,  B01J20/3475 ,  B01J2220/62

摘要： Systems and methods for managing effluent from recharging zirconium phosphate and/or zirconium oxide are provided. The systems and methods control the pH of the zirconium phosphate and zirconium oxide effluent to allow for safe disposal. The systems and methods provide for management of the recharger effluent pH while recharging zirconium phosphate and zirconium oxide either independently or concurrently.

摘要翻译： 提供了用于管理从磷酸氢锆和/或氧化锆充电的流出物的系统和方法。 系统和方法控制磷酸锆和氧化锆流出物的pH值，以便安全处置。 这些系统和方法提供了对充电器流出物pH的管理，同时独立地或同时地补充磷酸锆和氧化锆。

公开(公告)号：WO2015199767A1

公开(公告)日：2015-12-30

申请号：PCT/US2015/020046

申请日：2015-03-11

申请人： MEDTRONIC, INC. ,  GERBER, Martin, T. ,  HOBOT, Christopher, M.

发明人： GERBER, Martin, T. ,  HOBOT, Christopher, M.

IPC分类号： A61M1/16 ,  A61M1/34

CPC分类号： A61M1/1696 ,  A61M2205/18 ,  A61M2205/33 ,  B01D61/30 ,  B01D61/32 ,  B01J20/0211 ,  B01J20/34

摘要： A reserve zirconium phosphate module for continuing dialysis in the event the capacity of the original zirconium phosphate module is exceeded. The sorbent cartridge can have a sensor for detecting when the capacity of the zirconium phosphate material has been exceeded, and a valve assembly for diverting the flow of spent dialysate into the reserve module when needed. Any of the modules of the sorbent cartridge can be reusable and the sorbent materials therein recharged.

摘要翻译： 在超过原始磷酸锆模块的容量的情况下，用于持续透析的储备磷酸锆模块。 吸附剂盒可以具有用于检测何时已经超过了磷酸锆材料的容量的传感器，以及在需要时将用过的透析液流转移到储备模块中的阀组件。 吸附剂盒的任何模块可以是可重复使用的，并且其中的吸附剂材料被再充电。