公开(公告)号：WO2022026491A1

公开(公告)日：2022-02-03

申请号：PCT/US2021/043360

申请日：2021-07-28

Applicant: MEDTRONIC, INC.

Inventor： MOLINA, Rene A. ,  STANSLASKI, Scott R. ,  JACKSON, Jadin C. ,  PULLIAM, Christopher L. ,  PANKEN, Eric J. ,  CASE, Michelle A. ,  BECKER, Abbey Beuning Holt

IPC: A61N1/36

Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.

公开(公告)号：WO2022047382A1

公开(公告)日：2022-03-03

申请号：PCT/US2021/048449

申请日：2021-08-31

Applicant: MEDTRONIC, INC.

Inventor： RAIKE, Robert S. ,  JACKSON, Jadin C. ,  STANSLASKI, Scott R. ,  PANKEN, Eric J. ,  PULLIAM, Christopher L. ,  ABRAHAM, Timothy R. ,  CASE, Michelle A. ,  DASSBACH GREEN, Paula Andrea Elma ,  BECKER, Abbey Beuning Holt ,  MOLINA, Rene A.

IPC: A61N1/36 ,  A61B5/00

Abstract: Devices, systems, and techniques for identifying electrodes closest to a target region of tissue are described. In one example, a device includes sensing circuitry configured to sense electrical signals from a plurality of electrode combinations. Processing circuitry identifies a first electrode combination of a first subset of electrode combinations. Each electrode combination of the first subset of electrode combination includes electrodes located at different axial positions along a length of the medical lead. The processing circuitry identifies a second electrode combination of a second subset of electrode combinations. Each electrode combination of the second subset of electrode combinations includes electrodes located at a same axial position and different circumferential positions around a perimeter of the medical lead. The processing circuitry then determines a third electrode combination and controls delivery of electrical stimulation via the third electrode combination.

公开(公告)号：WO2021150612A1

公开(公告)日：2021-07-29

申请号：PCT/US2021/014185

申请日：2021-01-20

Applicant: MEDTRONIC, INC.

Inventor： MOLINA, Rene A. ,  RAIKE, Robert S. ,  STANSLASKI, Scott R.

IPC: A61N1/05 ,  A61N1/36 ,  A61N1/0529 ,  A61N1/0534 ,  A61N1/36067 ,  A61N1/36092 ,  A61N1/36132 ,  A61N1/36139 ,  A61N1/36171 ,  A61N1/36196

Abstract: Techniques, systems, and devices are disclosed for delivering stimulation therapy to a patient. In one example, a medical device determines a first set of stimulation parameters that define entrainment stimulation pulses configured to entrain electrical activity in a patient. The medical device may control a stimulation generator to generate the entrainment stimulation pulses according to the first set of stimulation parameters. The medical device may further determine a second set of stimulation parameters that define at least one desynchronization stimulation pulse configured to disrupt at least a portion of the electrical activity entrained by the entrainment stimulation pulses. The medical device may subsequently control the stimulation generator to generate the desynchronization stimulation pulse(s) according to the second set of stimulation parameters.

公开(公告)号：WO2023057861A1

公开(公告)日：2023-04-13

申请号：PCT/IB2022/059294

申请日：2022-09-29

Applicant: MEDTRONIC, INC.

Inventor： MOLINA, Rene A. ,  BECKER, Abbey Buening Holt

IPC: A61N1/05 ,  A61N1/36 ,  A61B5/374 ,  A61B5/293 ,  A61N1/0534 ,  A61N1/36067 ,  A61N1/36139 ,  A61N1/36178

Abstract: This disclosure is directed to devices, systems, and techniques for delivering electrical stimulation. In some examples, a system includes processing circuitry configured to: receive information representative of a bioelectric brain signal recorded from a brain of a patient; and determine, based on the information, at least one pathological frequency of the bioelectric brain signal. Additionally, the processing circuitry is configured to select, based on the at least one pathological frequency, a sequence of pulse bursts at a pulse burst frequency, the sequence of pulse bursts at least partially defining electrical stimulation deliverable to an area of a brain of a patient, wherein adjacent pulse bursts within the sequence comprise different intra-burst pulse frequencies; and control a medical device to deliver the electrical stimulation comprising the sequence of pulse bursts to the area of the brain of the patient.

公开(公告)号：WO2022271837A1

公开(公告)日：2022-12-29

申请号：PCT/US2022/034540

申请日：2022-06-22

Applicant: MEDTRONIC, INC.

Inventor： MOLINA, Rene A. ,  CASE, Michelle A. ,  DASSBACH, Paula A. ,  BECKER, Abbey B.H. ,  PULLIAM, Christopher L.

IPC: A61N1/05 ,  A61N1/36 ,  A61N1/0534 ,  A61N1/0551 ,  A61N1/36135 ,  A61N1/36182

Abstract: Implantable medical leads include rows of electrode segments where electrode segments within a given row may be a different size and/or adjacent electrode segments of adjacent rows may be of a different size. The arrangement of the electrode segments of different sizes may avoid intersections of the spaces between segments to reduce the size and/or number of blind spots that otherwise occur for delivery of stimulation signals and/or sensing of physiological signals. The electrode segments of different sizes may be of a same shape type but with different proportions.

公开(公告)号：WO2022026493A1

公开(公告)日：2022-02-03

申请号：PCT/US2021/043362

申请日：2021-07-28

Applicant: MEDTRONIC, INC.

Inventor： MOLINA, Rene A. ,  STANSLASKI, Scott R. ,  JACKSON, Jadin C. ,  PULLIAM, Christopher L. ,  PANKEN, Eric J. ,  CASE, Michelle A. ,  BECKER, Abbey Beuning Holt

IPC: A61N1/36

Abstract: Devices, systems, and techniques are described for identifying stimulation parameter values based on electrical stimulation that induces dyskinesia for the patient. For example, a method may include controlling, by processing circuitry, a medical device to deliver electrical stimulation to a portion of a brain of a patient, receiving, by the processing circuitry, information representative of an electrical signal sensed from the brain after delivery of the electrical stimulation, determining, by the processing circuitry and from the information representative of the electrical signal, a peak in a spectral power of the electrical signal at a second frequency lower than a first frequency of the electrical stimulation, and responsive to determining the peak in the spectral power of the electrical signal at the second frequency, performing, by the processing circuitry, an action.